{"title":"通过高分辨率四维HPCH实验,利用数据库挖掘和支持向量回归对牙龈癌细胞的DNA/RNA进行诊断,顺序分配牙龈癌细胞中13c标记的DNA/RNA","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000373","DOIUrl":null,"url":null,"abstract":"In the current research, diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells are investigated. Diagnosis of gum cancer in biopsy samples relies on morphological analysis using the expertise of histopathologists or cytologists who have many years’ experience in viewing these specimens. This is augmented by techniques which allow gum cancer specific markers to be visualized using diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells, where gene profiles can be visualized using microarray platforms. Characteristic translocations can be detected using fluorescent in situ hybridization (FISH), particularly in haematopathology. The use of optical methods to interrogate gum cancer cells is developing rapidly and diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells provides a new modality, which shows much promise.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"55 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"Diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells\",\"authors\":\"A. Heidari, R. Gobato\",\"doi\":\"10.15761/DOMR.1000373\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current research, diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells are investigated. Diagnosis of gum cancer in biopsy samples relies on morphological analysis using the expertise of histopathologists or cytologists who have many years’ experience in viewing these specimens. This is augmented by techniques which allow gum cancer specific markers to be visualized using diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells, where gene profiles can be visualized using microarray platforms. Characteristic translocations can be detected using fluorescent in situ hybridization (FISH), particularly in haematopathology. The use of optical methods to interrogate gum cancer cells is developing rapidly and diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells provides a new modality, which shows much promise.\",\"PeriodicalId\":10996,\"journal\":{\"name\":\"Dental, Oral and Maxillofacial Research\",\"volume\":\"55 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dental, Oral and Maxillofacial Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/DOMR.1000373\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000373","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells
In the current research, diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells are investigated. Diagnosis of gum cancer in biopsy samples relies on morphological analysis using the expertise of histopathologists or cytologists who have many years’ experience in viewing these specimens. This is augmented by techniques which allow gum cancer specific markers to be visualized using diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells, where gene profiles can be visualized using microarray platforms. Characteristic translocations can be detected using fluorescent in situ hybridization (FISH), particularly in haematopathology. The use of optical methods to interrogate gum cancer cells is developing rapidly and diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells provides a new modality, which shows much promise.