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引用次数: 0
摘要
癫痫是一种慢性非传染性脑部疾病,可影响所有年龄段的人。抗癫痫药物(AED)是大多数癫痫患者的主要治疗方法,其总体目标是防止癫痫发作而不产生副作用。癫痫药物治疗的管理措施之一是减少/失去癫痫发作,因此癫痫发作频率是实现最终结果的措施之一。本研究是一项对艾朗加大学医院门诊患者进行的观察性横断面研究,旨在探讨癫痫患者抗癫痫药物依从性水平与癫痫发作发生率之间的关系。本研究使用MGLS问卷(Morisky, Green, Levine依从性量表)对AED消费的依从性水平进行评估。基于MGLS问卷的依从性水平分为低、中或中等服从和高依从3个等级。观察癫痫患者的发作事件为近一个月内有无发作,数据来源于患者或家属访谈和日记发作。对40名被调查者的研究结果发现,使用MGLS问卷测量的依从性水平(多数依从性水平为中等)与癫痫患者癫痫发作的发生存在中度正相关(r = 0.423, p = 0.006 <0.05)。
Korelasi Tingkat Kepatuhan Konsumsi Obat Antiepilepsi Menggunakan Kuesioner MGLS (Morisky, Green, Levine Adherence Scale) dengan Frekwensi Kejang Pasien Epilepsi
Epilepsy is a chronic non-communicable brain disorder that can affect people of all ages. AED (antiepileptic drug) is the main therapy for most epilepsy patients with the overall goal being to prevent seizures without causing side effects. One measure of management of drug therapy in epilepsy is the decrease / loss of seizures, so that the frequency of seizures is one of the measures to achieve end-outcome. This study was an observational cross sectional study conducted on outpatients in Airlangga University Hospital, which aims to look at the relationship between the level of adherence using antiepileptic drugs with the incidence of seizures in epilepsy patients. The level of adherence with AED consumption in this study used the MGLS questionnaire (Morisky, Green, Levine Adherence Scale). The level of adherence based on the MGLS questionnaire was divided into 3 levels including low, medium or medium obedient and high compliant. The seizure events in epilepsy patients observed were the presence or absence of seizures during the past month, the data of which were obtained from patient or family interviews and from diary seizures. The results of the study of 40 respondents found that there was a moderate positive correlation between the level of adherence measured using the MGLS questionnaire whose majority level of adherence was moderate with the occurrence of seizures in epilepsy patients (r = 0.423 with p = 0.006 <0.05.