在40岁以下的狼疮肾炎患者和40岁以上的狼疮肾炎患者的形态学变量之间缺乏差异

Elnaz Marzbani, R. Valizadeh, N. Tavassoli, H. Nasri, Yassamin Rabiei
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摘要

这是一项横断面研究,对127例经肾活检证实的狼疮性肾炎患者按照ISN/RPS 2003狼疮性肾炎分级进行。我们研究了所有个体的人口统计数据,包括血清肌酐、24小时蛋白尿、年龄和性别。我们的研究显示血清肌酐、24小时蛋白尿和狼疮性肾炎(LN)类别在年龄小于或等于40岁和大于40岁之间没有差异。在本研究中,我们也发现免疫荧光研究中IgG、C3和C1q抗体沉积强度在40岁以下和40岁以上人群中无显著差异。因此,年龄小于或等于40岁与大于40岁之间LN的类别、活动或慢性百分比没有显著差异。此外,年龄小于等于40岁的患者与年龄大于40岁的患者的硬化性肾小球或月牙数目无显著差异。
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Lack of differences between morphological variables in age below 40 years versus more than 40 years in lupus nephritis patients
This is a cross-sectional investigation, which was carried out on 127 kidney biopsy proven lupus nephritis cases by lupus nephritis classification of ISN/RPS 2003. We studied demographic data of all individuals comprising serum creatinine, 24 hours proteinuria, age and gender. Our study showed no difference of serum creatinine and 24 hours proteinuria and lupus nephritis (LN) classes between age below or equal to 40 versus more than 40 years old. In this study also, we found no significant difference of antibody deposited intensity of IgG, C3 and C1q in immunofluorescence study in age below or equal to 40 versus more than 40 years old. Accordingly, no significant difference of LN classes, activity or chronicity percent between ages below or equal to 40 versus more than 40 years old. Moreover, no significant difference of number of sclerotic glomeruli or crescents among patients with ages below or equal to 40 versus more than 40 years old were detected.
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