免疫功能正常患者的隐球菌性脑膜炎

Syed Hassan Tanvir Ramzi, S. Saleem, Ubaidullah Ansari, Fnu Namal, Y. Kiran
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引用次数: 0

摘要

一种被称为隐球菌脑膜炎的真菌疾病通常被认为是一种机会性感染,影响免疫功能低下的人,特别是那些感染了艾滋病毒的人。许多问题都与它有关,包括广泛的疾病和神经系统疾病,如颅内高压、脑梗死、视力丧失和其他异常。这是一个18岁的男性病人,他表现为持续头痛和发烧。腰椎穿刺显示他有隐球菌感染。他的体检显示,没有已知的潜在疾病可能损害了他的免疫系统。然后使用印度墨水制剂对CSF进行隐球菌种类检测,结果呈阳性。患者入院,开始用两性霉素B抗真菌治疗,同时测定血清肌酐和电解质水平,给予两性霉素B第5天后,总症状明显改善。
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Cryptococcal Meningitis in An Immunocompetent Patient
A fungal illness called cryptococcal meningitis is most often thought of as an opportunistic infection that affects immunocompromised people, typically those who have HIV infection. Numerous problems are linked to it, including widespread illness and neurologic ones such as intracranial hypertension, cerebral infarcts, vision loss, and other abnormalities. Here is a case 18-year-old male patient, who presented with persistent headache and fever. A lumbar puncture revealed a cryptococcal infection in him. His workup indicated no known underlying illness that may have compromised his immune system. CSF was then tested for cryptococcal species using an Indian ink preparation, and the results were positive. He was admitted to the hospital for initiation of antifungal therapy with amphotericin B along with serial serum creatinine and electrolytes levels and after the 5th day of getting amphotericin B, he had shown remarkable improvement in total symptomatology.
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