Stain Materials’ Role in Biological Research: A Tool in Heath Care

Stains and staining methods significantly assist in diagnoses in medical research and health care. Certain color of a dye can identify the location of a tumor within a specimen. Applying histochemical-staining enabled morphological identification of fibrin in the lymphoid tissue during cancer progression. Staining methods in combination with the LSFM (light-sheet fluorescence microscopy) allowed tracing the drug penetration, development and spread of tumors. The Curcumin dye is in use for labelling and imaging of Aβ plaques in post-mortem brain tissue. Immunofluorescent staining methods are employed in detection of some important proteins in early diagnostic changes relevant to heart damage. The methods are developed in medical research to include stem cells and tissue engineering, cell cultures` properties and capabilities, connective tissues and extracellular matrix , nervous system , musculoskeletal system; respiratory system, liver and gastrointestinal tract, and male and female reproductive systems.