{"title":"tgf - β和CTGF介导的信号转导通路与纤维化","authors":"J. Tian, Fang Yang, Huiqin Liu","doi":"10.1109/ICBEB.2012.397","DOIUrl":null,"url":null,"abstract":"Transforming growth factor-beta (TGF-β) is one of the important cell factors which cause the fibrous function, and connective tissue growth factor (CTGF) is considered to be the downstream factor of TGF-β, mediates fibrosis of TGF-β. TGF-β induces the expression of CTGF through multiple signal transduction pathways in promoting fibrosis. This article provides a brief summary of the research progress in this area.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"7 1","pages":"913-916"},"PeriodicalIF":0.0000,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"TGF-Beta and CTGF Mediated Signal Transduction Pathway and Fibrosis\",\"authors\":\"J. Tian, Fang Yang, Huiqin Liu\",\"doi\":\"10.1109/ICBEB.2012.397\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Transforming growth factor-beta (TGF-β) is one of the important cell factors which cause the fibrous function, and connective tissue growth factor (CTGF) is considered to be the downstream factor of TGF-β, mediates fibrosis of TGF-β. TGF-β induces the expression of CTGF through multiple signal transduction pathways in promoting fibrosis. This article provides a brief summary of the research progress in this area.\",\"PeriodicalId\":6374,\"journal\":{\"name\":\"2012 International Conference on Biomedical Engineering and Biotechnology\",\"volume\":\"7 1\",\"pages\":\"913-916\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2012 International Conference on Biomedical Engineering and Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICBEB.2012.397\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2012 International Conference on Biomedical Engineering and Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICBEB.2012.397","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
TGF-Beta and CTGF Mediated Signal Transduction Pathway and Fibrosis
Transforming growth factor-beta (TGF-β) is one of the important cell factors which cause the fibrous function, and connective tissue growth factor (CTGF) is considered to be the downstream factor of TGF-β, mediates fibrosis of TGF-β. TGF-β induces the expression of CTGF through multiple signal transduction pathways in promoting fibrosis. This article provides a brief summary of the research progress in this area.
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