{"title":"制备姜黄素水包油纳米乳作为药物载体模板的方法","authors":"E. Marin, Briceño Mi, Georgescu Cc","doi":"10.4172/2155-952X.1000247","DOIUrl":null,"url":null,"abstract":"Curcumin has a wide spectrum of biological and pharmacological activities, which could be better exploited in numerous medical applications if it were not for its poor water-solubility. In this study, we describe a new method to improve curcumin solubility, using a combination of paraffin oil and ethanol. Further, we describe a systematic and efficient procedure to develop a formulation and a scalable mixing method in order to produce curcumin loaded oilin- water nanoemulsions that can be used as nanocapsule templates with potential biomedical applications.","PeriodicalId":15156,"journal":{"name":"Journal of biotechnology & biomaterials","volume":"3 1","pages":"1-8"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"Method to Produce Curcumin Oil-in-Water Nanoemulsions as Templates for Drug Carriers\",\"authors\":\"E. Marin, Briceño Mi, Georgescu Cc\",\"doi\":\"10.4172/2155-952X.1000247\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Curcumin has a wide spectrum of biological and pharmacological activities, which could be better exploited in numerous medical applications if it were not for its poor water-solubility. In this study, we describe a new method to improve curcumin solubility, using a combination of paraffin oil and ethanol. Further, we describe a systematic and efficient procedure to develop a formulation and a scalable mixing method in order to produce curcumin loaded oilin- water nanoemulsions that can be used as nanocapsule templates with potential biomedical applications.\",\"PeriodicalId\":15156,\"journal\":{\"name\":\"Journal of biotechnology & biomaterials\",\"volume\":\"3 1\",\"pages\":\"1-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biotechnology & biomaterials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2155-952X.1000247\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biotechnology & biomaterials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2155-952X.1000247","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Method to Produce Curcumin Oil-in-Water Nanoemulsions as Templates for Drug Carriers
Curcumin has a wide spectrum of biological and pharmacological activities, which could be better exploited in numerous medical applications if it were not for its poor water-solubility. In this study, we describe a new method to improve curcumin solubility, using a combination of paraffin oil and ethanol. Further, we describe a systematic and efficient procedure to develop a formulation and a scalable mixing method in order to produce curcumin loaded oilin- water nanoemulsions that can be used as nanocapsule templates with potential biomedical applications.
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