西地那非加曲马多致多形性红斑1例

A. Ghanbarzamani, E. Salehifar, Kaveh Kazemian
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引用次数: 0

摘要

在本报告中,我们报告了一位29岁的男性在使用西地那非和曲马多后5天出现EM。根据临床检查和病史,通过皮肤活检证实了EM的诊断,发现表皮内大疱充满纤维性渗出物,一些单核细胞和少量嗜酸性粒细胞。海绵状表皮表现为地衣样界面皮炎、嗜酸性海绵状病变和坏死松解,与电镜诊断一致。给患者开0.025%氟西诺酮软膏,治疗两周后病灶愈合。
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A Case of Erythema Multiforme Caused by Sildenafil Plus Tramadol
In this report, we present a 29-year-old man who experienced EM five days after using sildenafil and tramadol. Based on clinical examination and history, the diagnosis of EM was made confirmed via skin biopsy, which found intra-epidermal bulla filled by fibrinous exudate, some mononuclear cells, and a few eosinophils. The spongiotic epidermis showed lichenoid interface dermatitis, eosinophilic spongiosis, and necrolysis, consistent with EM diagnosis. Fluocinolone, 0.025% ointment, was prescribed for the patient, and the lesions healed after two weeks of treatment.
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