万隆Hasan Sadikin医院乳腺癌放疗患者概况

Atikah Larasati, Marhendra Satria Utama, Adji Kusumadjati
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引用次数: 0

摘要

背景:乳腺癌是全世界和印度尼西亚妇女中最常见的癌症。大多数患者到医院太晚,无法从乳腺癌治疗中获得最佳益处,其中放射治疗是基本方式之一。放射治疗是利用电离辐射的原理进行局部控制,以根除癌细胞的生长,从而减少复发的机会,提高存活率。一些副作用包括皮肤状况,可表现为皮肤红肿和干燥,疲劳,淋巴水肿和胸壁纤维化。在印度尼西亚,特别是在西爪哇,关于接受放射治疗的乳腺癌患者概况的数据和研究仍然有限。本研究旨在评估万隆哈桑萨迪金医院乳腺癌患者的概况。方法:采用回顾性描述性定量方法。抽样技术是对2018年1月1日至2019年12月31日期间在哈桑萨迪金综合医院放疗科医院癌症登记处登记的280例乳腺癌放疗患者的医疗记录进行总抽样。结果:接受放疗的乳腺癌患者以45 ~ 54岁年龄组居多(36.4%)。最常见的主诉是乳房肿块(66.4%),尤其是左乳肿块(45.0%)。局部晚期占22.5%,晚期占30.7%,伴有骨转移(10.6%),组织病理学亚型浸润性癌无特殊类型(IC-NST)占81.1%,分子亚型luminal B占9.6%。应用最广泛的治疗方法是全乳切除术(16.1%),新辅助化疗(62.9%)和完全辅助放疗(47.1%)结合LINAC外束放疗(EBRT)方法(71.1%)。结论:乳腺癌是Hasan Sadikin总医院的健康负担,仍然是国家卫生重点之一。需要进行进一步的管理评估和随访研究,以改善对患者的治疗实施并降低发病率
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Profile of Breast Cancer Patients with Radiotherapy in Hasan Sadikin Hospital Bandung
Background: Breast cancer is the most common cancer in women worldwide and in Indonesia. Most patients arrived at the hospital too late to receive the optimal benefit from breast cancer therapies, in which radiotherapy is one of the essential modalities. Radiotherapy is conducted as a local control by using the principle of ionizing radiation to eradicate the growth of cancer cells, hence reducing the chances of recurrence and enhancing survival rates. Some of the side effects include skin conditions that can manifest as redness and dry skin, fatigue, lymphedema, and chest wall fibrosis. Data and research on the profile of breast cancer patients with radiotherapy were still limited in Indonesia, particularly in West Java. This study aimed to assess the profile of breast cancer patients in Hasan Sadikin Hospital Bandung.Methods: This study was conducted with the retrospective descriptive quantitative method. The sampling technique was total sampling using 280 medical records of breast cancer patients with radiotherapy from January 1, 2018, until December 31, 2019, which were registered in the Hospital-Based Cancer Registry at the Radiotherapy Department, Hasan Sadikin General Hospital.Results: Breast cancer patients undergoing radiotherapy were mostly in the 45–54 years age group (36.4%). The most common chief complaint was a lump in the breast (66.4%), particularly in the left breast (45.0%). About 22.5% of all patients arrived at a locally advanced stage and 30.7% at an advanced stage with bone metastasis (10.6%), histopathological subtype Invasive Carcinoma No Special Type (IC-NST) (81.1%), and molecular subtype luminal B (9.6%). The most widely performed therapies were total mastectomy surgery (16.1%), neoadjuvant chemotherapy (62.9%), and complete adjuvant radiotherapy (47.1%) with External Beam Radiotherapy (EBRT) method using LINAC (71.1%).Conclusions: Breast cancer is a health burden in Hasan Sadikin General Hospital and remains one of the national health priorities. Further evaluation of management and follow-up studies need to be done to improve the implementation of therapies for patients and reduce the incidence rate
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