Comment prendre en charge les sujets à risque de développer une polyarthrite rhumatoïde ?

Rheumatoid arthritis (RA) is an uncurable chronic disease. Managing people at risk, i.e. before the disease starts, could possibly prevent its occurrence. The pre-clinical stages of RA are now identifiable, and this has allowed the development of clinical trials for prevention. In this article, we will present for each stage the therapeutic trials that have been conducted and are ongoing (corticosteroids, ritxumab, abatacept, atorvastatin, methotrexate and hydroxychloroquine) and then we will discuss the non-pharmacological measures that can be proposed in view of the literature (vitamin D and correction of environmental risk factors).