抗衰老药物的现状,特别是涉及管理更年期,在韩国补充和替代医学的一个组成部分

Hyun Kim, Hoon Kim, Jung-Ho Shin, S. Ku
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引用次数: 1

摘要

近年来,许多发展中国家的人口结构发生了变化,进入了老龄化社会。因此,抗衰老药物被认为对老年相关疾病的危险因素有有益的影响,受到了人们的广泛关注。补充和替代医学(CAM)已被普通民众广泛接受,因此在许多国家占卫生保健费用的很大一部分。激素治疗(HT)是缓解更年期症状的金标准,但在韩国,只有2.3%的更年期妇女接受激素治疗。许多其他妇女寻求替代方法,包括韩国传统药物、含有植物雌激素的产品,如黑升麻、大豆(异黄酮)、东葵、人参和月见草油。生物同质激素疗法(BHT)是用不同剂量的类固醇单独合成的疗法。其疗效尚未得到证实,但有报道称其有发生子宫内膜增生和乳腺癌的风险。其他涉及生活方式和行为干预的CAM方法包括锻炼、热量限制、减肥和“身心药物”(顺势疗法)。此外,展览还介绍了皮肤、整形和眼科的干预措施。医生们忽视了患者偏好“天然激素疗法”的新趋势,然而,他们应该意识到辅助激素疗法的利弊,并能够指导患者做出正确的选择。应该进行临床试验,并对每一种辅助医学实践进行评估。
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Current Status of Anti-Aging Medicine, Especially Involving Management of the Menopause, as a Component of Complementary and Alternative Medicine in Korea
Recently, many developing countries have had changes in the composition of population and have become aging societies. Therefore, anti-aging medicine which is believed to have beneficial effect on the risk factors of geriatric associated diseases has been paid much attention. Complementary and alternative medicine (CAM) has been widely accepted by the general population, and is consequently known to account for a large share of health care costs in many countries.Hormone therapy (HT) is the gold standard to alleviate menopausal symptoms, but only 2.3% of Korean menopausal women are on HT. Many other women seek alternative means, including Korean traditional medicine, phytoestrogen-containing products such as black cohosh, soy (isoflavone), Dong quai, Ginseng, and evening primrose oil. Bioidential hormone therapy (BHT) is HT with individually compounded recipes of steroids in various doses. Its efficacy is yet to be confirmed and the risks of developing endometrial hyperplasia and breast cancer have been reported. Other CAM methods involving lifestyle and behavioral interventions include exercise, caloric restriction, weight reduction, and ‘mind-body medicine (homeopathy).’ Dermatologic, plastic, and ophthalmologic interventions have been introduced through the exhibition, as well.Physicians have ignored this novel trend of patients preference to ‘natural hormonal therapy,’ however, they should be aware of the pros and cons of CAM and be able to guide their patients to make right choices. Clinical trials, and the evaluation of every CAM practice should be undertaken.
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