PATHOGENETIC ASPECTS OF THE USE OF LASER RADIATION IN THE TREATMENT OF CHRONIC HEPATITIS

The aim of the work was to study the effect of low-intensity laser radiation on the cytokine system, vascular endothelial function in patients with chronic hepatitis. All patients were divided into three groups: in the I th (control) group (30 people) only traditional drug therapy was used for treatment, patients of the II th group (45 people) along with drug therapy received intravenous laser therapy and the III group of patients (45 people) received a course of cutaneous laser therapy. The results of our study indicate that drug therapy in patients with CG is not accompanied by a significant improvement in the plasma levels of NOx, as well as Pro-inflammatory cytokines, and the inclusion of laser therapy in the complex of therapeutic measures contributes to a significant improvement in the plasma levels of NOx, eliminating the imbalance of cytokine regulation. Various methods of laser therapy improve the NOproducing function of the endothelium, improve the functional state of the vascular endothelium, have an immunomodulatory effect. НАУЧНЫЕ ВЕДОМОСТИ | ■; | Серия: Медицина. Фармация. 2019. Том 42, No 1 5 6 НАУЧНЫЕ ВЕДОМОСТИ у Серия: Медицина. Фармация. 2019. Том 42, No 1 Ключевые слова: дисфункция эндотелия, оксид азота, цитокины, хронический гепатит, низкоинтенсивная лазерная терапия.