Jagruti C. Patel, J. Bhatt, V. A. Javiya, Kamlesh Patel
{"title":"古吉拉特邦一家三级医疗机构分离的肠杆菌科细菌的抗菌敏感性模式","authors":"Jagruti C. Patel, J. Bhatt, V. A. Javiya, Kamlesh Patel","doi":"10.5580/b2b","DOIUrl":null,"url":null,"abstract":"Objectives: Present study was undertaken to assess antibiotic susceptibility patterns of Enterobacteriaceae at a tertiary care hospital in Gujarat, India. Methods: Out of 276 culture positive samples, 154 samples of Enterbacteriaceae were examined and 11 different types of specimen were collected. Microbial sensitivity testing was done using disk diffusion test with Escherichia coli NCTC 10418 as per CLSI guidelines. Results: Highest Enterobacteriacae infections were found in urine followed by pus and sputum. Enterobacteriacae species demonstrated marked resistance against monotherapy of penicillins and cephalosporins. Combination of ampicillin, amoxicillin and third generation cephalosporins with sulbactam and monotherapy of amikacin showed higher sensitivity to Enterobacteriacae infections but maximum sensitivity was shown by carbapenems. Conclusions: Urinary tract infection was the most common hospital acquired infection. Co-administration of -lactamase inhibitor markedly expanded the anti-microbial sensitivity of penicillins and cephalosporins. Use of amikacin and carbapenems should be restricted to severe nosocomial infections to avoid rapid emergence of resistant strains.","PeriodicalId":22514,"journal":{"name":"The Internet journal of microbiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":"{\"title\":\"Anti-Microbial Susceptibility Patterns of Enterobacteriaceae Isolated From A Tertiary Care Unit In Gujarat\",\"authors\":\"Jagruti C. Patel, J. Bhatt, V. A. Javiya, Kamlesh Patel\",\"doi\":\"10.5580/b2b\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives: Present study was undertaken to assess antibiotic susceptibility patterns of Enterobacteriaceae at a tertiary care hospital in Gujarat, India. Methods: Out of 276 culture positive samples, 154 samples of Enterbacteriaceae were examined and 11 different types of specimen were collected. Microbial sensitivity testing was done using disk diffusion test with Escherichia coli NCTC 10418 as per CLSI guidelines. Results: Highest Enterobacteriacae infections were found in urine followed by pus and sputum. Enterobacteriacae species demonstrated marked resistance against monotherapy of penicillins and cephalosporins. Combination of ampicillin, amoxicillin and third generation cephalosporins with sulbactam and monotherapy of amikacin showed higher sensitivity to Enterobacteriacae infections but maximum sensitivity was shown by carbapenems. Conclusions: Urinary tract infection was the most common hospital acquired infection. Co-administration of -lactamase inhibitor markedly expanded the anti-microbial sensitivity of penicillins and cephalosporins. Use of amikacin and carbapenems should be restricted to severe nosocomial infections to avoid rapid emergence of resistant strains.\",\"PeriodicalId\":22514,\"journal\":{\"name\":\"The Internet journal of microbiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet journal of microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/b2b\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet journal of microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/b2b","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-Microbial Susceptibility Patterns of Enterobacteriaceae Isolated From A Tertiary Care Unit In Gujarat
Objectives: Present study was undertaken to assess antibiotic susceptibility patterns of Enterobacteriaceae at a tertiary care hospital in Gujarat, India. Methods: Out of 276 culture positive samples, 154 samples of Enterbacteriaceae were examined and 11 different types of specimen were collected. Microbial sensitivity testing was done using disk diffusion test with Escherichia coli NCTC 10418 as per CLSI guidelines. Results: Highest Enterobacteriacae infections were found in urine followed by pus and sputum. Enterobacteriacae species demonstrated marked resistance against monotherapy of penicillins and cephalosporins. Combination of ampicillin, amoxicillin and third generation cephalosporins with sulbactam and monotherapy of amikacin showed higher sensitivity to Enterobacteriacae infections but maximum sensitivity was shown by carbapenems. Conclusions: Urinary tract infection was the most common hospital acquired infection. Co-administration of -lactamase inhibitor markedly expanded the anti-microbial sensitivity of penicillins and cephalosporins. Use of amikacin and carbapenems should be restricted to severe nosocomial infections to avoid rapid emergence of resistant strains.