{"title":"大卫·德克斯特·珀金斯(1919-2007)","authors":"A. Radford, N. Raju, D. Jacobson","doi":"10.4148/1941-4765.1099","DOIUrl":null,"url":null,"abstract":"Obituary of David Dexter Perkins Creative Commons License This work is licensed under a Creative Commons Attribution-Share Alike 4.0 License. This obituary is available in Fungal Genetics Reports: http://newprairiepress.org/fgr/vol54/iss1/5 Fungal Genetics Newsletter 54 In Press Obituaries David Dexter Perkins (1919-2007) David Perkins died on January 2, 2007 after a short illness. Two comprehensive obituaries, documenting the lives and scientific careers of David and his wife Dorothy Newmeyer Perkins (1922-2007) have been published elsewhere, and it is not our intention to duplicate those accounts, merely to commend them (Davis 2007, Genetics 175: 1-6; Raju 2007, J. Genetics, Vol. 86, in press). This is an account focusing specifically on David’s involvement with the Fungal Genetics Stock Center, Neurospora Newsletter and its successor, the Fungal Genetics Newsletter, over the past forty-five years. David was one of the five members of the committee that organized the first Neurospora Information Conference in 1961, the predecessor of the Fungal Genetics Conferences. A direct outgrowth of this first conference was the creation of the Neurospora Newsletter. David was always a strong supporter of the Newsletter, as a journal for the fast but refereed publication of short research notes, new linkage data, maps, FGSC stock lists relating to Neurospora, and subsequently, from 1986, to fungi in general. His own first item in the Newsletter was in volume 2, with a note on the favourable nature of the asci of bis x bis crosses for meiotic cytogenetics. Over the following four decades and more, David published eighty-five items in the Newsletter, covering research reports, novel techniques, new linkage data, regular updates of the complete linkage maps of Neurospora crassa, guidelines for gene nomenclature and obituaries for fellow pioneers in the sphere of Neurospora genetics. David was a tower of strength for the three editors of the Newsletter since its inception, Barbara Bachmann, Peter Russell and Matthew Sachs, not only as a contributor and as a reviewer of contributed papers but also in providing encouragement and moral support when needed. In addition to David’s Newsletter contributions, he played a major role in establishing and nurturing the Fungal Genetics Stock Center. Kevin McCluskey, the present curator of FGSC, compiled David’s major contributions to the stock center. Beginning in 1960, David deposited 3150 strains in the FGSC collection including strains 1-192. In 1999, he deposited most of his 3900 stains from wild collection. Thus it is not unusual to see the initials DDP associated with most of the Neurospora strains in the FGSC collection. David’s natural populations of Neurospora provide a rich source of variability that contributed to several major discoveries: heterokaryon incompatibility genes, transposable elements, senescence inducing plasmids, meiotic drive causing Spore killer elements etc. David was always frugal both in private life and in science; he walked or bicycled to work, and always used glass plates, culture tubes and pipets that were washed and reused, again and again. He devised numerous simple methods for storing strains on silica gel, developed multiply marked “multicent\" strains for reliable and quick mapping of centromere-linked mutations, and incorporated three reciprocal chromosome rearrangements into a single strain “alcoy\" for mapping various mutant genes. He was also the main driving force behind the Neurospora Methods Manual (ed. Deborah Bell-Pederson), which is available on line at the FGSC site. The Newsletter, like the whole Neurospora community, has lost a friend, an adviser, and its figurehead. David led the community in his quiet, self-effacing way, through good and bad times, from the early days of map construction and mapping functions, studies on chromosome rearrangements, spore killers, population biology, to the genome sequence and beyond. His continuous and evolving role is well-documented in his contributions in the pages of the Newsletter and elsewhere. David will be best remembered as one of the founders and pillars of our vibrant community and its most tireless advocate. Alan Radford, Biological Sciences, Univ. of Leeds, Leeds LS2 9JT, UK Namboori B. Raju, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA David J. Jacobson, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA Published by New Prairie Press, 2017","PeriodicalId":12490,"journal":{"name":"Fungal Genetics Reports","volume":"65 1","pages":"14"},"PeriodicalIF":0.0000,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"David Dexter Perkins (1919-2007)\",\"authors\":\"A. Radford, N. Raju, D. Jacobson\",\"doi\":\"10.4148/1941-4765.1099\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Obituary of David Dexter Perkins Creative Commons License This work is licensed under a Creative Commons Attribution-Share Alike 4.0 License. This obituary is available in Fungal Genetics Reports: http://newprairiepress.org/fgr/vol54/iss1/5 Fungal Genetics Newsletter 54 In Press Obituaries David Dexter Perkins (1919-2007) David Perkins died on January 2, 2007 after a short illness. Two comprehensive obituaries, documenting the lives and scientific careers of David and his wife Dorothy Newmeyer Perkins (1922-2007) have been published elsewhere, and it is not our intention to duplicate those accounts, merely to commend them (Davis 2007, Genetics 175: 1-6; Raju 2007, J. Genetics, Vol. 86, in press). This is an account focusing specifically on David’s involvement with the Fungal Genetics Stock Center, Neurospora Newsletter and its successor, the Fungal Genetics Newsletter, over the past forty-five years. David was one of the five members of the committee that organized the first Neurospora Information Conference in 1961, the predecessor of the Fungal Genetics Conferences. A direct outgrowth of this first conference was the creation of the Neurospora Newsletter. David was always a strong supporter of the Newsletter, as a journal for the fast but refereed publication of short research notes, new linkage data, maps, FGSC stock lists relating to Neurospora, and subsequently, from 1986, to fungi in general. His own first item in the Newsletter was in volume 2, with a note on the favourable nature of the asci of bis x bis crosses for meiotic cytogenetics. Over the following four decades and more, David published eighty-five items in the Newsletter, covering research reports, novel techniques, new linkage data, regular updates of the complete linkage maps of Neurospora crassa, guidelines for gene nomenclature and obituaries for fellow pioneers in the sphere of Neurospora genetics. David was a tower of strength for the three editors of the Newsletter since its inception, Barbara Bachmann, Peter Russell and Matthew Sachs, not only as a contributor and as a reviewer of contributed papers but also in providing encouragement and moral support when needed. In addition to David’s Newsletter contributions, he played a major role in establishing and nurturing the Fungal Genetics Stock Center. Kevin McCluskey, the present curator of FGSC, compiled David’s major contributions to the stock center. Beginning in 1960, David deposited 3150 strains in the FGSC collection including strains 1-192. In 1999, he deposited most of his 3900 stains from wild collection. Thus it is not unusual to see the initials DDP associated with most of the Neurospora strains in the FGSC collection. David’s natural populations of Neurospora provide a rich source of variability that contributed to several major discoveries: heterokaryon incompatibility genes, transposable elements, senescence inducing plasmids, meiotic drive causing Spore killer elements etc. David was always frugal both in private life and in science; he walked or bicycled to work, and always used glass plates, culture tubes and pipets that were washed and reused, again and again. He devised numerous simple methods for storing strains on silica gel, developed multiply marked “multicent\\\" strains for reliable and quick mapping of centromere-linked mutations, and incorporated three reciprocal chromosome rearrangements into a single strain “alcoy\\\" for mapping various mutant genes. He was also the main driving force behind the Neurospora Methods Manual (ed. Deborah Bell-Pederson), which is available on line at the FGSC site. The Newsletter, like the whole Neurospora community, has lost a friend, an adviser, and its figurehead. David led the community in his quiet, self-effacing way, through good and bad times, from the early days of map construction and mapping functions, studies on chromosome rearrangements, spore killers, population biology, to the genome sequence and beyond. His continuous and evolving role is well-documented in his contributions in the pages of the Newsletter and elsewhere. David will be best remembered as one of the founders and pillars of our vibrant community and its most tireless advocate. Alan Radford, Biological Sciences, Univ. of Leeds, Leeds LS2 9JT, UK Namboori B. Raju, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA David J. Jacobson, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA Published by New Prairie Press, 2017\",\"PeriodicalId\":12490,\"journal\":{\"name\":\"Fungal Genetics Reports\",\"volume\":\"65 1\",\"pages\":\"14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fungal Genetics Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4148/1941-4765.1099\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fungal Genetics Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4148/1941-4765.1099","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本作品采用知识共享署名-相同方式共享4.0许可协议。这个讣告可以在真菌遗传学报告中找到:http://newprairiepress.org/fgr/vol54/iss1/5真菌遗传学通讯54在新闻讣告大卫·德克斯特·珀金斯(1919-2007)大卫·珀金斯于2007年1月2日因病去世。两份全面的讣告,记录了大卫和他的妻子多萝西·纽迈耶·珀金斯(Dorothy Newmeyer Perkins, 1922-2007)的生活和科学生涯,已经在其他地方发表过,我们无意复制这些记录,只是赞扬他们(戴维斯2007,遗传学175:1-6;Raju 2007, J.遗传学,第86卷,出版中)。这是一个帐户特别关注大卫的参与真菌遗传学库存中心,神经孢子通讯和它的继任者,真菌遗传学通讯,在过去的45年。David是1961年组织第一届神经孢子菌信息会议(真菌遗传学会议的前身)的委员会的五名成员之一。第一次会议的直接成果是《神经孢子菌通讯》的创刊。David一直是《通讯》的坚定支持者,作为一份快速但经过审查的期刊,出版了与神经孢子菌有关的简短研究笔记、新的连锁数据、地图、FGSC库存清单,随后,从1986年开始,出版了真菌。他在《通讯》的第一篇文章是在第二卷,其中提到了他的x - bis杂交对减数分裂细胞遗传学的有利性质。在接下来的40多年里,David在《通讯》上发表了85篇文章,包括研究报告、新技术、新的连锁数据、粗神经孢子虫完整连锁图谱的定期更新、基因命名指南和神经孢子虫遗传学领域先驱们的讣告。自《时事通讯》创刊以来,大卫一直是三位编辑——芭芭拉·巴赫曼、彼得·罗素和马修·萨克斯——的坚强后盾,他不仅是投稿者和投稿论文的审稿人,而且在需要的时候给予鼓励和道义上的支持。除了大卫的通讯贡献,他在建立和培育真菌遗传库存中心发挥了重要作用。现任FGSC馆长凯文·麦克卢斯基(Kevin McCluskey)汇编了大卫对股票中心的主要贡献。从1960年开始,David在FGSC收集中存放了3150株菌株,包括菌株1-192。1999年,他从野外收集的3900个污点中提取了大部分。因此,在FGSC收集的大多数神经孢子菌菌株中,看到首字母DDP并不罕见。David的神经孢子虫自然种群提供了丰富的变异来源,这些变异促成了几个重大发现:异核不相容基因、转座因子、诱导衰老的质粒、导致孢子杀伤因子的减数分裂驱动等。大卫在私人生活和科学研究上都很节俭;他走路或骑自行车去上班,总是使用玻璃板、培养管和移液管,这些都是经过清洗和重复使用的,一次又一次。他设计了许多简单的方法将菌株储存在硅胶上,开发了多重标记的“多中心”菌株,用于可靠和快速地定位着丝粒连锁突变,并将三个互惠染色体重排合并到一个菌株“alcoy”中,用于定位各种突变基因。他也是神经孢子菌方法手册(Deborah Bell-Pederson主编)的主要推动者,该手册可在FGSC网站上在线获得。《通讯》就像整个神经孢子菌界一样,失去了一位朋友、一位顾问和一位有名无实的领袖。从早期的地图构建和地图功能、染色体重排、孢子杀手、种群生物学的研究,到基因组序列等,大卫以他安静、谦逊的方式领导着这个社区,经历了好与坏的时期。他在时事通讯和其他地方的贡献充分记录了他不断发展的角色。作为我们这个充满活力的社区的创始人和支柱之一,以及最不知疲倦的倡导者,大卫将被人们铭记。Namboori B. Raju,斯坦福大学生物科学系,斯坦福,CA 94305,美国David J. Jacobson,斯坦福大学生物科学系,斯坦福,CA 94305,美国新草原出版社出版,2017
Obituary of David Dexter Perkins Creative Commons License This work is licensed under a Creative Commons Attribution-Share Alike 4.0 License. This obituary is available in Fungal Genetics Reports: http://newprairiepress.org/fgr/vol54/iss1/5 Fungal Genetics Newsletter 54 In Press Obituaries David Dexter Perkins (1919-2007) David Perkins died on January 2, 2007 after a short illness. Two comprehensive obituaries, documenting the lives and scientific careers of David and his wife Dorothy Newmeyer Perkins (1922-2007) have been published elsewhere, and it is not our intention to duplicate those accounts, merely to commend them (Davis 2007, Genetics 175: 1-6; Raju 2007, J. Genetics, Vol. 86, in press). This is an account focusing specifically on David’s involvement with the Fungal Genetics Stock Center, Neurospora Newsletter and its successor, the Fungal Genetics Newsletter, over the past forty-five years. David was one of the five members of the committee that organized the first Neurospora Information Conference in 1961, the predecessor of the Fungal Genetics Conferences. A direct outgrowth of this first conference was the creation of the Neurospora Newsletter. David was always a strong supporter of the Newsletter, as a journal for the fast but refereed publication of short research notes, new linkage data, maps, FGSC stock lists relating to Neurospora, and subsequently, from 1986, to fungi in general. His own first item in the Newsletter was in volume 2, with a note on the favourable nature of the asci of bis x bis crosses for meiotic cytogenetics. Over the following four decades and more, David published eighty-five items in the Newsletter, covering research reports, novel techniques, new linkage data, regular updates of the complete linkage maps of Neurospora crassa, guidelines for gene nomenclature and obituaries for fellow pioneers in the sphere of Neurospora genetics. David was a tower of strength for the three editors of the Newsletter since its inception, Barbara Bachmann, Peter Russell and Matthew Sachs, not only as a contributor and as a reviewer of contributed papers but also in providing encouragement and moral support when needed. In addition to David’s Newsletter contributions, he played a major role in establishing and nurturing the Fungal Genetics Stock Center. Kevin McCluskey, the present curator of FGSC, compiled David’s major contributions to the stock center. Beginning in 1960, David deposited 3150 strains in the FGSC collection including strains 1-192. In 1999, he deposited most of his 3900 stains from wild collection. Thus it is not unusual to see the initials DDP associated with most of the Neurospora strains in the FGSC collection. David’s natural populations of Neurospora provide a rich source of variability that contributed to several major discoveries: heterokaryon incompatibility genes, transposable elements, senescence inducing plasmids, meiotic drive causing Spore killer elements etc. David was always frugal both in private life and in science; he walked or bicycled to work, and always used glass plates, culture tubes and pipets that were washed and reused, again and again. He devised numerous simple methods for storing strains on silica gel, developed multiply marked “multicent" strains for reliable and quick mapping of centromere-linked mutations, and incorporated three reciprocal chromosome rearrangements into a single strain “alcoy" for mapping various mutant genes. He was also the main driving force behind the Neurospora Methods Manual (ed. Deborah Bell-Pederson), which is available on line at the FGSC site. The Newsletter, like the whole Neurospora community, has lost a friend, an adviser, and its figurehead. David led the community in his quiet, self-effacing way, through good and bad times, from the early days of map construction and mapping functions, studies on chromosome rearrangements, spore killers, population biology, to the genome sequence and beyond. His continuous and evolving role is well-documented in his contributions in the pages of the Newsletter and elsewhere. David will be best remembered as one of the founders and pillars of our vibrant community and its most tireless advocate. Alan Radford, Biological Sciences, Univ. of Leeds, Leeds LS2 9JT, UK Namboori B. Raju, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA David J. Jacobson, Dept. of Biological Sciences, Stanford Univ., Stanford, CA 94305, USA Published by New Prairie Press, 2017