功能能力成分不能预测帕金森病患者的跌倒风险

G. Moraca, D. Orcioli-Silva, V. S. Beretta, Vinicius C. Zampier, P. C. Santos, L. T. Gobbi
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引用次数: 0

摘要

背景:跌倒是帕金森病(PwPD)患者的一个严重问题,它会损害功能能力和生活质量。虽然一些预测跌倒风险的因素已经得到证实,但需要对个体和组合的功能能力成分进行调查,以确定更详细的跌倒风险预测方法。目的:验证个体和组合功能容量指标预测PwPD患者跌倒风险的能力。方法:96名个体参与了这项队列研究。功能能力通过Berg平衡量表、计时起身和行走、6分钟步行和坐立测试进行评估。在未来12个月的随访中,跌倒至少一次的参与者被认为是跌倒者。一位训练有素的评估员每周记录一次坠落的发生情况。使用Mann-Whitney U检验、t检验和卡方检验来比较患者与非患者。使用功能容量成分(个体和组合)的受试者操作特征曲线来预测跌倒风险。结果:36例(37.5%)PwPD为跌倒者,56例跌倒,60例(62.5%)为非跌倒者。两组之间的功能容量成分没有差异。综合功能能力分量不能预测PwPD患者的跌倒风险(曲线下面积= 0.52;P = 0.77)。当单独分析时,这些成分也无法预测跌倒风险。结论:我们的研究结果表明,功能能力成分,无论是单独的还是综合的,都不能很好地预测PwPD患者的跌倒风险。跌伤的多因素特征和跌伤分类可能影响跌伤风险的预测,值得进一步研究。
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Functional capacity components do not predict fall risk in people with Parkinson's disease
BACKGROUND: Falls are an impactful problem for people with Parkinson's disease (PwPD), impairing the functional capacity and quality of life. Although some predictors of fall risk have been evidenced, the investigation of functional capacity components individual and combined is needed to a more detailed approach to identify fall risk prediction. AIM: To verify the ability of individual and combined functional capacity components in predicting fall risk in PwPD. METHOD: Ninety-six individuals participated in this cohort study. Functional capacity was assessed by Berg Balance Scale, Timed Up and Go, Six-Minute Walk, and Sit-to-Stand tests. The participants who fell at least once during the prospective follow-up of 12 months were considered fallers. A trained evaluator registered the fall’s occurrence weekly. Mann-Whitney U, t-tests, and chi-square tests were used to compare fallers versus non-fallers. Receiver Operating Characteristics curves of functional capacity components (individual and combined) were performed to predict fall risk. RESULTS: Thirty-six (37.5%) PwPD were classified as fallers, being recorded 56 falls, and 60 (62.5%) as non-fallers. There are no differences in functional capacity components between groups. The combined functional capacity components were not able to predict fall risk in PwPD (area under the curve = 0.52; p = 0.77). These components were also unable to predict fall risk when analyzed individually. CONCLUSION: Our results indicated that functional capacity components, individual and combined, are not good predictors of fall risk in PwPD. The multifactorial characteristics of falls and the falls classification might affect the fall risk prediction and should be further investigated.
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