胰肾联合移植术后移植胰腺存活超过18年1例并文献复习

Xia Lu, N. Gong, F. Zeng, Z. Chen, Zhishui Chen
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摘要

目的探讨胰肾联合移植(SPK)术后长期生存的影响因素及治疗策略。方法回顾1例spk术后长期生存率,并结合相关文献分析其影响因素。结果spk术后10年,患者因排斥反应丧失移植肾,行二次肾移植。移植的胰腺功能良好,存活了18年多。结论严格的术前筛查,采用成熟的手术入路,积极处理各种围手术期并发症,加强受者健康教育,提高依从性,长期定期随访,有利于提高SPK受者和移植物的长期生存。关键词:胰肾联合移植;糖尿病肾病;拒绝;定期随访
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A case report of transplanted pancreas survival longer than 18 years after simultaneous pancreas-kidney transplantation and literature review
Objective To explore the influencing factors and treatment strategies of long-term survival after simultaneous pancreas and kidney transplantation (SPK). Methods One case of long-term post-SPK survival was reviewed and its influencing factors were analyzed along with the relevant literature. Results At 10 years post-SPK, the patient lost transplanted kidney due to rejection and underwent secondary kidney transplantation. The transplanted pancreas functioned well and has survived for more than 18 years. Conclusions Strict preoperative screening, adopting mature surgical approaches, aggressive managements of various perioperative complications, strengthening of health education of recipients, improving of compliance and long-term regular follow-ups are conducive for enhancing long-term survival of recipients and grafts of SPK. Key words: Simultaneous pancreas and kidney transplantation; Diabetic nephropathy; Rejection; Regular follow-up
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