{"title":"一种从地衣中提取的新的酚类化合物。黑尔","authors":"H. B. L. Chi, Bui Van Muoi, N. Thu, N. Phung","doi":"10.1002/VJCH.202060096","DOIUrl":null,"url":null,"abstract":"Chemical investigation of the lichen Parmotrema praesorediosum (Nyl.) Hale led to isolate six phenolic compounds including praesorediosic (1), orcinol (2), orselinic acid (3), lecanorin (4), isolecanoric acid (5) and virensic acid (6). Among them, compound 1 appeared to be found for the first time in the nature. The structure of these compounds was elucidated by spectroscopic analyses of HRESIMS and NMR as well as the comparison of their NMR data with those in the literature. These compounds were evaluated for their cytotoxicity using sulforhodamine-B assay against HeLa (human epithelial carcinoma), NCI-H460 (human lung cancer), HepG2 (liver hepatocellular carcinoma) and MCF-7 (human breast cancer) cell lines.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":"16 1","pages":"47-51"},"PeriodicalIF":1.3000,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A new phenolic compound from the lichen Parmotrema praesorediosum (Nyl.) Hale\",\"authors\":\"H. B. L. Chi, Bui Van Muoi, N. Thu, N. Phung\",\"doi\":\"10.1002/VJCH.202060096\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chemical investigation of the lichen Parmotrema praesorediosum (Nyl.) Hale led to isolate six phenolic compounds including praesorediosic (1), orcinol (2), orselinic acid (3), lecanorin (4), isolecanoric acid (5) and virensic acid (6). Among them, compound 1 appeared to be found for the first time in the nature. The structure of these compounds was elucidated by spectroscopic analyses of HRESIMS and NMR as well as the comparison of their NMR data with those in the literature. These compounds were evaluated for their cytotoxicity using sulforhodamine-B assay against HeLa (human epithelial carcinoma), NCI-H460 (human lung cancer), HepG2 (liver hepatocellular carcinoma) and MCF-7 (human breast cancer) cell lines.\",\"PeriodicalId\":23525,\"journal\":{\"name\":\"Vietnam Journal of Chemistry\",\"volume\":\"16 1\",\"pages\":\"47-51\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2021-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vietnam Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/VJCH.202060096\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vietnam Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/VJCH.202060096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A new phenolic compound from the lichen Parmotrema praesorediosum (Nyl.) Hale
Chemical investigation of the lichen Parmotrema praesorediosum (Nyl.) Hale led to isolate six phenolic compounds including praesorediosic (1), orcinol (2), orselinic acid (3), lecanorin (4), isolecanoric acid (5) and virensic acid (6). Among them, compound 1 appeared to be found for the first time in the nature. The structure of these compounds was elucidated by spectroscopic analyses of HRESIMS and NMR as well as the comparison of their NMR data with those in the literature. These compounds were evaluated for their cytotoxicity using sulforhodamine-B assay against HeLa (human epithelial carcinoma), NCI-H460 (human lung cancer), HepG2 (liver hepatocellular carcinoma) and MCF-7 (human breast cancer) cell lines.
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