Vajira医院妊娠期打鼾的患病率及其母胎结局

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The secondary outcome was to investigate the associations between pregnancy outcome and habitual snorer or those identified as high risk by the Thai Berlin Questionnaire.\n\nMaterials and Methods: Three hundred eighty-two singleton pregnant women aged at least 18 years and at least 33 weeks of gestational age were recruited from the antenatal care clinic at Vajira Hospital, Navamindradhiraj University, between November 2021 and September 2022 and filled out the Thai Berlin Questionnaire. The 382 pregnant women were identified the presence of snoring or high risk of OSA in the previous month. Medical records, including demographic information and pregnancy outcomes, were collected, and analyzed.\n\nResults: The prevalence of snoring was 31.4% in the third trimester of pregnancy of which 27% were pregnancy onset snoring and 4.4% were chronic onset snoring. Habitual snoring was significantly different from non-snoring in regard to the requirement for positive-pressure ventilation in newborns (aOR 6.67, 95% CI 1.2 to 35.54). The high risk group had significantly more pregnancy induced hypertension than the low risk group (aOR 5.96, 95% CI 2.15 to 16.5), gestational hypertension (aOR 13.6, 95% CI 2.1 to 86.8), preeclampsia (aOR 4.07, 95% CI 1.09 to 15.2), severe preeclampsia (aOR 4.9, 95% CI 1.15 to 20.93), preterm birth (aOR 6.21, 95% CI 1.58 to 24.42), and low birth weight of newborn (aOR 6.09, 95% CI 2.5 to 14.87).\n\nConclusion: The prevalence of snoring among Thai pregnant women was comparable to previous Western studies. 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摘要

背景:打鼾是与阻塞性睡眠呼吸暂停有关的重要症状,并增加不良妊娠结局的风险。在泰国,怀孕期间打鼾的流行程度尚不确定。确定打鼾的患病率和特征可以减少打鼾的患病率,改善妊娠结局。目的:主要结局是确定泰国孕妇在妊娠晚期(包括妊娠和慢性发作)打鼾的患病率。次要结果是调查妊娠结局与习惯性打鼾者或泰国柏林问卷确定的高风险者之间的关系。材料与方法:在2021年11月至2022年9月期间,从Navamindradhiraj大学Vajira医院的产前保健诊所招募了382名年龄至少为18岁,孕龄至少为33周的单胎孕妇,并填写了泰国柏林问卷。382名孕妇在前一个月被确定有打鼾或阻塞性睡眠呼吸暂停的高风险。收集并分析了包括人口统计信息和妊娠结局在内的医疗记录。结果:妊娠晚期打鼾发生率为31.4%,其中妊娠性打鼾占27%,慢性打鼾占4.4%。在新生儿正压通气需求方面,习惯性打鼾组与非打鼾组差异有统计学意义(aOR为6.67,95% CI为1.2 ~ 35.54)。高危组妊高征发生率明显高于低危组(aOR 5.96, 95% CI 2.15 ~ 16.5)、妊娠期高血压发生率(aOR 13.6, 95% CI 2.1 ~ 86.8)、先兆子痫发生率(aOR 4.07, 95% CI 1.09 ~ 15.2)、重度先兆子痫发生率(aOR 4.07, 95% CI 1.15 ~ 20.93)、早产发生率(aOR 6.21, 95% CI 1.58 ~ 24.42)、新生儿低出生体重发生率(aOR 6.09, 95% CI 2.5 ~ 14.87)。结论:泰国孕妇打鼾的患病率与之前的西方研究相当。筛查有症状风险的孕妇可能提供早期机会,降低打鼾的患病率和不良妊娠结局。关键词:打鼾;怀孕时打鼾;妊娠结局
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Prevalence of Snoring in Pregnancy and Its Maternal-Fetal Outcomes at Vajira Hospital
Background: Snoring is an important symptom that is associated with obstructive sleep apnea and increases the risk of adverse pregnancy outcomes. In Thailand, the prevalence of snoring during pregnancy is uncertain. Determining the prevalence and characteristics may reduce the prevalence of snoring and improve pregnancy outcomes. Objective: The primary outcome was to determine the prevalence of snoring in Thai pregnant women in the third trimester, including pregnancy and chronic onset. The secondary outcome was to investigate the associations between pregnancy outcome and habitual snorer or those identified as high risk by the Thai Berlin Questionnaire. Materials and Methods: Three hundred eighty-two singleton pregnant women aged at least 18 years and at least 33 weeks of gestational age were recruited from the antenatal care clinic at Vajira Hospital, Navamindradhiraj University, between November 2021 and September 2022 and filled out the Thai Berlin Questionnaire. The 382 pregnant women were identified the presence of snoring or high risk of OSA in the previous month. Medical records, including demographic information and pregnancy outcomes, were collected, and analyzed. Results: The prevalence of snoring was 31.4% in the third trimester of pregnancy of which 27% were pregnancy onset snoring and 4.4% were chronic onset snoring. Habitual snoring was significantly different from non-snoring in regard to the requirement for positive-pressure ventilation in newborns (aOR 6.67, 95% CI 1.2 to 35.54). The high risk group had significantly more pregnancy induced hypertension than the low risk group (aOR 5.96, 95% CI 2.15 to 16.5), gestational hypertension (aOR 13.6, 95% CI 2.1 to 86.8), preeclampsia (aOR 4.07, 95% CI 1.09 to 15.2), severe preeclampsia (aOR 4.9, 95% CI 1.15 to 20.93), preterm birth (aOR 6.21, 95% CI 1.58 to 24.42), and low birth weight of newborn (aOR 6.09, 95% CI 2.5 to 14.87). Conclusion: The prevalence of snoring among Thai pregnant women was comparable to previous Western studies. Screening pregnant women at risk of the symptom may provide an early chance to lower the prevalence of snoring and adverse pregnancy outcomes. Keywords: Snoring; Snoring in pregnancy; Pregnancy outcomes
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