头颈癌:在孟买一家三级肿瘤医院治疗的患者的生存分析

G. Balasubramaniam, Rajshree H. Gaidhani, Mitali Anand Sapkal, S. Saoba, R. Dikshit, P. Chaturvedi
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引用次数: 0

摘要

本研究的主要目的是报告在塔塔纪念医院(TMH)见到的头颈癌病例的生存率。本研究包括2012年至2014年期间在孟买TMH看到的大量头颈癌病例。该研究包括4351例口腔癌、766例口咽癌、612例下咽癌、544例喉癌和244例鼻咽癌。采用TNM分组分期确定临床病变程度。[2]在本研究中,除声带外,大部分患者诊断为III期和IV期,下唇和舌前部分较少。因此,提供的治疗要么是手术,要么是联合放疗或化疗。口腔癌的总体3年生存率为26-43%,口咽癌为23-33%,下咽癌为22-28%,喉癌为28-53%,鼻咽癌为44%。在本研究中,预后因疾病部位和亚位点而异。结果的差异是预防活动范围的一个指标,可以重申头颈癌的更好预后。
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Head-and-neck cancer: Survival analysis of patients treated in a tertiary cancer hospital in Mumbai
The main objective of this study is to report on the survival rates of head-and-neck cancer cases seen in Tata memorial hospital (TMH). In the present study comprises of a large number of head-and-neck cancer cases seen in TMH, Mumbai, during the years 2012– 14. The study included 4351 oral cancer, 766 oropharyngeal cancer, 612 hypopharyngeal cancer, 544 laryngeal cancers, and 244 nasopharyngeal cancer. TNM group staging was used to determine the clinical extent of disease.[2] In the study, a major proportion of patients were diagnosed in Stage III and stage IV, except in vocal cord and to a lesser extent in lower lip and anterior tongue. Thus, the treatment offered is either only surgery or in combination with radiotherapy or chemotherapy. The overall 3-year survival rates for oral cancer were 26–43%, 23–33% for oropharyngeal cancer, 22–28% for hypoharyngeal cancer, 28–53% for laryngeal cancers, and 44% for nasopharyngeal cancer. Prognosis differed by site of disease and subsites in this study. The differences in outcome are an indicator of the scope of prevention activities that could be reiterated for better prognosis of head-and-neck cancer.
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