{"title":"奈瑟氏脑膜炎菌血清群W引起幼儿原发性脑膜炎球菌感染性关节炎及文献回顾","authors":"","doi":"10.47485/2767-5416.1008","DOIUrl":null,"url":null,"abstract":"Since 2009, there has been a serious increase in the number of meningococcal infections in Europe caused by the serotype W meningococcus (MenW:cc11). Invasive meningococcal disease is typically known to cause severe sepsis or meningitiswith high overall mortality rates of 10% despite adequate antimicrobial treatment. Focal infections such as arthritis incidentally occur as a complication of systemic disease. Method We describe a rare case of primary meningococcal W135 arthritis in a 2-year-old patient. Results Arthrocentesis of the right Ankle while patient was under anesthesia, yielded grossly purulent fluid, so we made arthrotomy and drainage. The culture from synovial fluid revealed N. meningitidis.The status of the patient improved after surgical drainage and intravenous antibiotic therapy. She recovered completely after 1 month. Discussion.Atypical clinical presentation is associated with higher case fatality rates and can lead to misdiagnoses.an unusual presentation of invasive meningococcal infection and the early identification of the bacteria, combined with the correct treatment, prevent the complications and even death.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"37 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neisseira meningitidis Serogroup W causing primary meningococcal septic arthritis in a toddler and review of the literature\",\"authors\":\"\",\"doi\":\"10.47485/2767-5416.1008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Since 2009, there has been a serious increase in the number of meningococcal infections in Europe caused by the serotype W meningococcus (MenW:cc11). Invasive meningococcal disease is typically known to cause severe sepsis or meningitiswith high overall mortality rates of 10% despite adequate antimicrobial treatment. Focal infections such as arthritis incidentally occur as a complication of systemic disease. Method We describe a rare case of primary meningococcal W135 arthritis in a 2-year-old patient. Results Arthrocentesis of the right Ankle while patient was under anesthesia, yielded grossly purulent fluid, so we made arthrotomy and drainage. The culture from synovial fluid revealed N. meningitidis.The status of the patient improved after surgical drainage and intravenous antibiotic therapy. She recovered completely after 1 month. Discussion.Atypical clinical presentation is associated with higher case fatality rates and can lead to misdiagnoses.an unusual presentation of invasive meningococcal infection and the early identification of the bacteria, combined with the correct treatment, prevent the complications and even death.\",\"PeriodicalId\":94090,\"journal\":{\"name\":\"Journal of medical clinical case reports\",\"volume\":\"37 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of medical clinical case reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47485/2767-5416.1008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medical clinical case reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47485/2767-5416.1008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neisseira meningitidis Serogroup W causing primary meningococcal septic arthritis in a toddler and review of the literature
Since 2009, there has been a serious increase in the number of meningococcal infections in Europe caused by the serotype W meningococcus (MenW:cc11). Invasive meningococcal disease is typically known to cause severe sepsis or meningitiswith high overall mortality rates of 10% despite adequate antimicrobial treatment. Focal infections such as arthritis incidentally occur as a complication of systemic disease. Method We describe a rare case of primary meningococcal W135 arthritis in a 2-year-old patient. Results Arthrocentesis of the right Ankle while patient was under anesthesia, yielded grossly purulent fluid, so we made arthrotomy and drainage. The culture from synovial fluid revealed N. meningitidis.The status of the patient improved after surgical drainage and intravenous antibiotic therapy. She recovered completely after 1 month. Discussion.Atypical clinical presentation is associated with higher case fatality rates and can lead to misdiagnoses.an unusual presentation of invasive meningococcal infection and the early identification of the bacteria, combined with the correct treatment, prevent the complications and even death.