ELTGOL和Flutter®对支气管扩张患者动态和静态肺容量和分泌物清除的影响

F. Guimarães, Vanessa J. R. Moço, S. L. S. Menezes, Cristina Márcia Dias, R. E. B. Salles, A. Lopes
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引用次数: 15

摘要

背景:虽然呼吸物理治疗被认为是治疗高分泌患者的基础,但很少有证据表明其在支气管扩张患者的生理和治疗效果。目的:评价ELTGOL和扑动VRP1®对支气管扩张患者动态和静态肺容量的急性生理影响,并研究这些技术在痰清除中的作用。方法:纳入临床及影像学诊断为支气管扩张的患者。患者按随机顺序进行了三次干预,两次干预之间间隔一周。在所有干预之前,患者吸入两次100微克沙丁胺醇。对照方案和干预(ELTGOL和Flutter VRP1®)前后均有5分钟的咳嗽期。每次咳嗽后,患者通过肺活量测定和体积描记术评估动态和静态肺容量。在干预期间和第二次咳嗽期间收集痰分泌物,并按其干重进行量化。结果:10例患者,男2例,女8例,平均年龄55.9±18.1岁。使用Flutter VRP1®和ELTGOL后,肺残气量(RV)、功能残气量(FRC)和总肺活量(TLC)均显著降低(p<0.05)。与对照组和颤振VRP1®相比,ELTGOL期间的痰量更高(p<0.05)。结论:ELTGOL和Flutter VRP1®技术可显著降低肺过度充气,但只有ELTGOL可增加支气管扩张患者肺分泌物的清除。
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Efeitos da ELTGOL e do Flutter® nos volumes pulmonares dinâmicos e estáticos e na remoção de secreção de pacientes com bronquiectasia
Background: Although respiratory physical therapy is considered fundamental in the treatment of hypersecretive patients, there is little evidence of its physiological and therapeutic effects in bronchiectasis patients. Objective: To evaluate the acute physiological effects of ELTGOL and Flutter VRP1® in dynamic and static lung volumes in patients with bronchiectasis and, secondarily, to study the effect of these techniques in sputum elimination. Methods: Patients with clinical and radiological diagnosis of bronchiectasis were included. Patients underwent three interventions in a randomized order and with a one-week washout interval between them. Before all interventions patients inhaled two puffs of 100 mcg of salbutamol. There was a cough period of five minutes before and after the control protocol and the interventions (ELTGOL and Flutter VRP1®). After each cough series patients underwent assessments of dynamic and static lung volumes by spirometry and plethysmography. The expectorated secretions were collected during the interventions and during the second cough series, and quantified by its dry weight. Results: We studied 10 patients, two males and eight females (mean age: 55.9±18.1 years). After using Flutter VRP1®and ELTGOL there was a significant decrease in residual volume (RV), functional residual capacity (FRC) and total lung capacity (TLC) (p<0.05). There was a higher sputum production during ELTGOL compared with Control and Flutter VRP1® (p<0.05). Conclusion: The ELTGOL and Flutter VRP1® techniques acutely reduced lung hyperinflation, but only the ELTGOL increased the removal of pulmonary secretions from patients with bronchiectasis.
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