{"title":"转基因棉籽对Wistar大鼠90天重复剂量口服毒性研究","authors":"Priya Singh","doi":"10.46624/ajptr.2019.v9.i3.003","DOIUrl":null,"url":null,"abstract":"GM derived seed is one type of powered test item. It is used in 90 day repeat oral toxicity studies. Powered is administered orally to wistar rats for a period of 90 days. This study also compared the profile of the GM derived cotton seed with the non GM derived cotton seed at the highest does tested. The study was performed to generate information on major systemic toxic effects (if any), target organs and an estimate of the No Observed Effect Level (NOEL) / No Observed Adverse Effect Level (NOAEL) and also reversibility of observed changes, if any, after discontinuation of treatment with the Test Items.","PeriodicalId":7701,"journal":{"name":"American Journal of PharmTech Research","volume":"70 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"90 Day Repeat DOSE Oral Toxicity Study of GM Derived Cotton Seed In Wistar Rats\",\"authors\":\"Priya Singh\",\"doi\":\"10.46624/ajptr.2019.v9.i3.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"GM derived seed is one type of powered test item. It is used in 90 day repeat oral toxicity studies. Powered is administered orally to wistar rats for a period of 90 days. This study also compared the profile of the GM derived cotton seed with the non GM derived cotton seed at the highest does tested. The study was performed to generate information on major systemic toxic effects (if any), target organs and an estimate of the No Observed Effect Level (NOEL) / No Observed Adverse Effect Level (NOAEL) and also reversibility of observed changes, if any, after discontinuation of treatment with the Test Items.\",\"PeriodicalId\":7701,\"journal\":{\"name\":\"American Journal of PharmTech Research\",\"volume\":\"70 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-06-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of PharmTech Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46624/ajptr.2019.v9.i3.003\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of PharmTech Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46624/ajptr.2019.v9.i3.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
90 Day Repeat DOSE Oral Toxicity Study of GM Derived Cotton Seed In Wistar Rats
GM derived seed is one type of powered test item. It is used in 90 day repeat oral toxicity studies. Powered is administered orally to wistar rats for a period of 90 days. This study also compared the profile of the GM derived cotton seed with the non GM derived cotton seed at the highest does tested. The study was performed to generate information on major systemic toxic effects (if any), target organs and an estimate of the No Observed Effect Level (NOEL) / No Observed Adverse Effect Level (NOAEL) and also reversibility of observed changes, if any, after discontinuation of treatment with the Test Items.
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