{"title":"达那唑的微生物转化","authors":"M. Choudhary, Azizuddin, Atta-ur-rahman","doi":"10.1080/10575630290019994","DOIUrl":null,"url":null,"abstract":"Danazol (17 -hydroxy-17 -pregna-2,4-dien-20-yno-[2,3- d ] isoxazole) ( 1 ) on fermentation with Fusarium lini , Aspergillus niger , and Cephalosporium aphidicola yielded 17 -hydroxy-2-(hydroxymethyl)-17- -pregn-4-en-20-yn-3-one ( 2 ) and 17 -hydroxy-2-(hydroxymethyl)-17 -pregna-1,4-dien-20-yn-3-one ( 3 ), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"465 1","pages":"101 - 106"},"PeriodicalIF":0.0000,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"22","resultStr":"{\"title\":\"Microbial Transformation of Danazol\",\"authors\":\"M. Choudhary, Azizuddin, Atta-ur-rahman\",\"doi\":\"10.1080/10575630290019994\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Danazol (17 -hydroxy-17 -pregna-2,4-dien-20-yno-[2,3- d ] isoxazole) ( 1 ) on fermentation with Fusarium lini , Aspergillus niger , and Cephalosporium aphidicola yielded 17 -hydroxy-2-(hydroxymethyl)-17- -pregn-4-en-20-yn-3-one ( 2 ) and 17 -hydroxy-2-(hydroxymethyl)-17 -pregna-1,4-dien-20-yn-3-one ( 3 ), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.\",\"PeriodicalId\":18873,\"journal\":{\"name\":\"Natural Product Letters\",\"volume\":\"465 1\",\"pages\":\"101 - 106\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"22\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/10575630290019994\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/10575630290019994","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
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