成人T细胞白血病/淋巴瘤:关于一个病例

Carlos Lázaro Perona , Enrique Alcalde García , María Teresa Sanz-Casla , Elena Hernández Álvarez , Fiorella Medina Salazar , María Ángeles Cuadrado Cenzual
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引用次数: 0

摘要

成人t细胞白血病/淋巴瘤是成人成熟的外周t细胞白血病,与人类逆转录病毒HTLV-1感染有关,表现为高度可变的全身和皮肤表现。据估计,HTLV-1在全世界至少影响5-10万人,其在流行地区的地理分布与ATLL流行密切相关。成人t细胞白血病/淋巴瘤根据其临床特点分为不同的临床类型,其中急性型和淋巴瘤型预后最差。由于受影响个体的非特异性症状,成人t细胞白血病/淋巴瘤的鉴别诊断可能很困难。临床分析实验室可以通过外周涂片观察成人t细胞白血病/淋巴瘤的病理细胞来帮助诊断。
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Leucemia/linfoma de células T del adulto: a propósito de un caso

Adult T-cell leukaemia/lymphoma is a mature peripheral T-cell leukaemia of adults associated with infection by the human retrovirus HTLV-1 that presents with highly variable systemic and cutaneous manifestations. HTLV-1 is estimated to affect at least 5-10 million people worldwide, and its geographic distribution in endemic regions is closely related to ATLL prevalence. Adult T-cell leukaemia/lymphoma is classified into different clinical types according to its clinical characteristics, with acute and lymphomatous types having the worst prognosis. Differential diagnosis of adult T-cell leukaemia/lymphoma can be difficult due to the non-specific symptoms in affected individuals. The Clinical Analysis laboratory can help initiate the diagnosis by visualising pathognomonic cells for adult T-cell leukaemia/lymphoma in a peripheral smear.

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