以正硅酸胆碱稳定剂为基础的口服补剂对皮肤、毛发和指甲影响的临床研究

P. M. Campos, G. Favaretto
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引用次数: 2

摘要

近年来,市场上发布了各种各样的膳食补充剂,承诺对健康有益,并具有功能特性。由于某些食品成分对皮肤老化过程、皮肤、头发和指甲的健康外观的潜在影响,涉及营养的新趋势已得到强调。考虑到人们对改善头发、皮肤和指甲外观的需求日益增长,以及人们对使用营养化妆品的兴趣日益增加,本研究的目的是评估口服正硅酸胆碱稳定剂的补充。为此,我们进行了一项随机、安慰剂对照的临床试验。经伦理委员会批准,选择了60名年龄在40岁和65岁之间的女性,将她们分为两组(治疗组和安慰剂组)。用于评估的补充剂每日剂量为400毫克正硅酸胆碱稳定剂,持续3个月。在治疗前(基底- t0)和治疗后30,60和90天进行分析,并评估志愿者的真皮层结构特征,头发的机械特性和有效性感知。结果显示,治疗组在治疗90天后真皮层回声增强。因此,它证明了治疗增加了皮肤的密度。此外,高分辨率图像显示皮肤微浮雕改善和皮肤粗糙度改善。头发的抵抗力也有所增强,治疗组的志愿者报告皮肤、头发和指甲都有所改善。最后,本研究建议口服含有正硅酸胆碱稳定的营养品作为增加皮肤密度、改善头发和指甲状况的有效产品,作为局部治疗的补充。
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Influence of an Oral Supplementation Based on Orthosilicic Acid Choline-Stabilized on Skin, Hair and Nails: A Clinical Study with Objective Approach
In recent years, various dietary supplements have been released in the market with the promise of health benefits and functional properties. New trends involving nutrition have been highlighted due to the potential effects of certain food ingredients in the cutaneous aging process, the healthy appearance of skin, hair and nails. Looking at the growing demand for improvement in the appearance of hair, skin and nails and the increased interest of the population by use of nutricosmetics, the aim of this study was to evaluate an oral supplementation with orthossilicic acid choline-stabilized. For this, it was done a randomized, placebo-controlled clinical test. After approval of the ethics committee, were selected 60 women, aged 40 and 65 and they were divided into two groups (treatment and placebo). The daily dose of the supplement for evaluation was 400 mg of orthossilicic acid choline-stabilized for a period of 3 months. Analyzes were done before the treatment (basal-T0) and after 30, 60 and 90 days of treatment and it were evaluated the structural characteristics of the dermis, the mechanical properties of hair and the perception of effectiveness by the volunteers. According to the results, it was observed for the treatment group an increase in echogenicity of the dermis after 90 days of treatment. Thus, it proved that the treatment increased the density of the skin. In addition, the high resolution images showed improvement in skin micro relief and an improvement in skin roughness. There was also increased resistance of the hair and volunteers of treatment group reported improvement in skin, hair and nails. Finally, the oral supplementation of the nutricosmetic with orthossilicic acid choline-stabilized can be suggested as an effective product to increase skin density and to improve hair and nails conditions, complementary to topical treatments.
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