{"title":"铬酸氧化扁桃酸乙酯的动力学研究","authors":"D. Jha, G. V. Bakore","doi":"10.1039/J29710001166","DOIUrl":null,"url":null,"abstract":"Oxidation of ethyl mandelate with chromic acid is of the first order with respect to oxidant, ester, and hydrogen ions. The thermodynamic parameters for oxidation have been evaluated. The hydrolysis under similar conditions is slower than oxidation. The main product of oxidation is Ph·CO·CO2Et. The rate of hydrolysis and products rule out the possibility of hydrolysis before oxidation. A mechanism involving C–H bond rupture in the rate-determining step has been suggested.","PeriodicalId":17268,"journal":{"name":"Journal of The Chemical Society B: Physical Organic","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Kinetics of oxidation of ethyl mandelate by chromic acid\",\"authors\":\"D. Jha, G. V. Bakore\",\"doi\":\"10.1039/J29710001166\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Oxidation of ethyl mandelate with chromic acid is of the first order with respect to oxidant, ester, and hydrogen ions. The thermodynamic parameters for oxidation have been evaluated. The hydrolysis under similar conditions is slower than oxidation. The main product of oxidation is Ph·CO·CO2Et. The rate of hydrolysis and products rule out the possibility of hydrolysis before oxidation. A mechanism involving C–H bond rupture in the rate-determining step has been suggested.\",\"PeriodicalId\":17268,\"journal\":{\"name\":\"Journal of The Chemical Society B: Physical Organic\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1971-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of The Chemical Society B: Physical Organic\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1039/J29710001166\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Chemical Society B: Physical Organic","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/J29710001166","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Kinetics of oxidation of ethyl mandelate by chromic acid
Oxidation of ethyl mandelate with chromic acid is of the first order with respect to oxidant, ester, and hydrogen ions. The thermodynamic parameters for oxidation have been evaluated. The hydrolysis under similar conditions is slower than oxidation. The main product of oxidation is Ph·CO·CO2Et. The rate of hydrolysis and products rule out the possibility of hydrolysis before oxidation. A mechanism involving C–H bond rupture in the rate-determining step has been suggested.
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