{"title":"基于肠道菌群的生物转化在中药研发中的作用","authors":"Xin Liu","doi":"10.33552/APPR.2018.01.000514","DOIUrl":null,"url":null,"abstract":"Introduction Traditional Chinese Medicine (TCM) is of great significance to the research and development of new drugs due to its various active components. Meanwhile, as the focus of current research, biotransformation greatly stimulates the investigation of TCM. Intestine is the primary place for the metabolism of oral drugs in the human body, where a number of parasite bacteria flora play an inevitable role in the biotransformation of drugs. Thus, it is obviously that the biotransformation based on intestinal flora is a powerful tool in the development of TCM.","PeriodicalId":8291,"journal":{"name":"Archives of Pharmacy & Pharmacology Research","volume":"17 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of Biotransformation Based on Intestinal Flora in the Research and Development of TCM\",\"authors\":\"Xin Liu\",\"doi\":\"10.33552/APPR.2018.01.000514\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction Traditional Chinese Medicine (TCM) is of great significance to the research and development of new drugs due to its various active components. Meanwhile, as the focus of current research, biotransformation greatly stimulates the investigation of TCM. Intestine is the primary place for the metabolism of oral drugs in the human body, where a number of parasite bacteria flora play an inevitable role in the biotransformation of drugs. Thus, it is obviously that the biotransformation based on intestinal flora is a powerful tool in the development of TCM.\",\"PeriodicalId\":8291,\"journal\":{\"name\":\"Archives of Pharmacy & Pharmacology Research\",\"volume\":\"17 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Pharmacy & Pharmacology Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33552/APPR.2018.01.000514\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Pharmacy & Pharmacology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33552/APPR.2018.01.000514","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Role of Biotransformation Based on Intestinal Flora in the Research and Development of TCM
Introduction Traditional Chinese Medicine (TCM) is of great significance to the research and development of new drugs due to its various active components. Meanwhile, as the focus of current research, biotransformation greatly stimulates the investigation of TCM. Intestine is the primary place for the metabolism of oral drugs in the human body, where a number of parasite bacteria flora play an inevitable role in the biotransformation of drugs. Thus, it is obviously that the biotransformation based on intestinal flora is a powerful tool in the development of TCM.