低生育能力男性吸食大麻人群中精氨酸参数的比较研究

Carlos Aulesa , Victoria Vega , Henar Balbuena , Jose Ramón Alonso , Pedro Jiménez , Jordi Ramis , Jose María Gris
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引用次数: 0

摘要

这项工作的目的是发现大麻使用在低生育能力人群中的流行程度,并对一组习惯性大麻使用者的低生育能力患者与一组嵌套的非使用者的对照病例进行精图参数的比较前瞻性研究。材料和方法研究了2320名男性,其中70%来自初级保健中心,30%来自医院门诊。使用SCA®自动精液分析仪进行精子浓度和活力分析。通过应用一种称为“病例-对照嵌套”的新型统计方法进行了比较研究,这是一种混合病例-对照变异。结果计算了低生育能力男性人群中大麻使用的流行程度。对吸食大麻组和对照组的精液值进行统计分析,两者之间没有显著差异。结论在研究的低生育能力男性群体中,有10.26%的人习惯吸食大麻。在我们的研究结果中,没有观察到两组研究之间的显著差异,因此我们正在考虑新的精子功能测试的额外表现,以解释在一些使用大麻的患者中观察到的生育能力低下,他们的精细胞图正常。
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Estudio comparativo de los parámetros del seminograma en una población de varones subfértiles consumidores de marihuana

Introduction

The aim of this work, is to find the prevalence of marijuana use in a subfertile population, and to carry out a comparative prospective study of the seminogram parameters of a group of subfertile patients, who are habitual marijuana users, versus a group of nested control cases of non-users.

Material and methods

2320 men were studied, 70% of patients from Primary Care Centers and 30% from hospital outpatient consultations. The analysis of sperm concentration and motility was carried out with a SCA® automated semen analyzer. The comparative study has been carried out, by applying a novel statistical methodology called «case-control nested», which is a hybrid case-control variation.

Results

The prevalence of marijuana use has been calculated in a population of subfertile men. Statistical analysis of the semen values of the group of marijuana users versus the control group shows that there are no significant differences between them.

Conclusions

In the group of subfertile men studied, a prevalence of 10.26% of habitual marijuana users was observed. In our results, no significant differences were observed between the two groups studied, so we are considering the additional performance of new sperm functionalism tests, to explain the subfertility that has been observed in some of these patients who use marijuana, who present a normal seminogram.

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