椰子椰壳提取物溶液溶液溶液的配方和测试。它的浓度有940种不同于葡萄球菌aurecus ATCC 25923

Febriana Endah Permata Sari, Siti Aisiyah, Destik Wulandari
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引用次数: 0

摘要

沐浴露是可以用来保护皮肤免受金黄色葡萄球菌感染的制剂之一。具有抗菌活性的植物是椰子皮,其中含有单宁、类黄酮和多酚类化合物。单宁具有抑制金黄色葡萄球菌生长的活性。本研究旨在确定卡波波尔940的变化对液体皂制剂的影响。液体皂制剂具有抗菌活性,找出哪些配方具有最好的物理质量。以70%乙醇为溶剂,采用浸渍法提取椰子皮提取物。配方中椰子皮提取物的浓度为1.6%,卡波波尔940的浓度变化为0.5%、1%、1.5%。物理质量检查包括感官测试、均匀性测试、pH测试、粘度测试、泡沫稳定性测试和游离碱测试。采用扩散孔法检测液体皂制剂的抗菌活性,所得数据采用SPSS程序进行分析。卡波醇浓度940的变化会影响液体皂制剂的物理质量,卡波醇浓度的增加会影响粘度、泡沫稳定性和游离碱。各配方抗菌活性均为21.23 (F4);20.22 (F5);19.37 (F6)。物理质量和抑菌力最好的配方为卡波酚浓度为940 / 0.5%的配方4。
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FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN SABUN CAIR EKSTRAK SABUT KELAPA (Cocos nucifera L. ) DENGAN VARIASI KONSENTRASI CARBOPOL 940 TERHADAP BAKTERI Staphylococcus aureus ATCC 25923
Shower gel is one of the preparations that can be used to protect the skin from Staphylococcus aureus bacterial infection. Plants that have antibacterial activity are coconut husk, the compounds contained are tannins, flavonoids, and polyphenols. Tannins have the activity of inhibiting the growth of Staphylococcus aureus bacteria. This study aims to determine the influence of Carbopol 940 variations on liquid soap preparations. Liquid soap preparations have antibacterial activity, find out which formulas have the best physical quality. Coconut husk extract was obtained by maceration method using 70% ethanol solvent. The concentration of coconut husk extract in the formula is 1.6% with a variation in the concentration of Carbopol 940 which is 0.5%, 1%, 1.5%. Physical quality examination includes organoleptic test, homogeneity test, pH test, viscosity, foam stability test, and free alkali test. Testing the antibacterial activity of liquid soap preparations using the method of diffusion of wells, the data obtained by analysis using the SPSS program. Variations in carbopol concentration 940 affect the physical quality of liquid soap preparations, the increasing concentration of carbopol affects viscosity, foam stability, and free alkali. All formulas have antibacterial activity of 21.23 (F4); 20.22 (F5); 19.37 (F6). The formula with the best physical quality and inhibitory power is formula 4 with a carbopol concentration of 940 of 0.5%.
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