儿童过敏性紫癜伴胃肠道症状的治疗

Rizki Luthfia Wardhani, Siti Ariffatus Saroh
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引用次数: 0

摘要

过敏性紫癜(HSP)是一种儿童全身性血管炎,以小血管中多核白细胞的炎症浸润为特征,随后出现IgA1免疫沉积。热休克流行率约为每10万名儿童3-27例。热休克的炎症过程引起缺血和出血过程,其特征为非血小板减少性紫癜、关节痛、胃肠道问题和肾脏损害。这个过程被称为白细胞破裂性血管炎。一个10岁的男孩来到Dr. Sayidiman Magetan医院急诊室,表现为弥漫性腹痛和身体紫癜性皮肤病变。主诉开始时双腿出现红色皮疹,随后逐渐扩展到双手、大腿和臀部,持续出现严重腹部不适、恶心、头晕、发烧,患者还出现棕黑色大便。经医学检查,诊断为过敏性紫癜,伴有胃肠道症状。病人在医院住了六天,病情有所好转。
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Management of Henoch-Schonlein Purpura with Gastrointestinal Manifestations in Children
Henoch-Schonlein Purpura (HSP) is systemic vasculitis in children, hallmark by inflammatory infiltration of polymonuclear leukocytes in small blood vessels, followed by IgA1 immune deposits. HSP prevalence is approximately 3-27 cases per 100,000 children. The inflammatory process in HSP causes an ischemia and hemorrhagic process characterized by non-thrombocytopenia purpura, arthralgia, gastrointestinal problems, and kidney impairment. This process is called leukocytoclastic vasculitis. A 10-year-old boy came to ER of Dr. Sayidiman Magetan Hospital presenting with diffuse abdominal pain and purpura skin lesions in body. The complaint started with a red rash on both legs, then progressively extended to both hands, thighs, and buttocks, and continued with severe abdominal discomfort, nausea, dizziness, fever, and the patient also experienced a brownish-black stool. The patient was diagnosed with Henoch-Schonlein purpura with gastrointestinal manifestations based on medical examination. The patient stayed for six days at the hospital, and the condition improved.
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