1例接受奥玛单抗治疗的哮喘患者感染新冠肺炎病例报告

Ümmügülsüm Dikici, Ö. Özdemir
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摘要

新型冠状病毒感染大流行迅速进入我们的生活,并为这种感染定义了合并症,其进展伴随着严重的肺部受累。由于其多因素病理生理,哮喘已成为最令人好奇和研究的疾病之一,其在COVID-19中的合并症存在争议。虽然文献中有假设认为过敏性哮喘具有保护作用,但也有假设认为,如果患者出现过敏性哮喘症状,病程会更严重。我们的患者20岁,被诊断为过敏性哮喘,有不完全过敏原免疫治疗史,使用奥玛珠单抗1年症状得到控制,在COVID-19感染后存活,没有出现咳嗽或其他哮喘发作症状,没有住院。通过介绍这个病例,我们希望有助于理解哮喘、奥玛珠单抗治疗和COVID-19之间的关系。
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Covid-19 Infection in An Asthma Patient Receiving Omalizumab: Case Report
The new coronavirus infection pandemic entered our lives rapidly and comorbid diseases were defined for this infection, which progressed with severe lung involvement. Due to its multifactorial pathophysiology, asthma has become one of the most curious and researched diseases and its comorbidity in COVID-19 is controversial. Although there are hypotheses in the literature stating that allergic asthma is protective, there are also hypotheses that argue that if the patient develops symptoms in allergic asthma, the course will be more severe. Our 20-year-old patient, who was diagnosed with allergic asthma, had a history of incomplete allergen immunotherapy, and whose symptoms were under control with omalizumab for 1 year, survived the COVID-19 infection without developing cough or other asthma attack symptoms, without being admitted to hospital. By presenting this case, we wanted to contribute to the understanding of the relationship between asthma, omalizumab treatment and COVID-19.
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