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COMPARISON OF GALACTOGRAPHY, ULTRASONOGRAPHY AND CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING FINDINGS WITH PATHOLOGY RESULTS IN PATIENTS WITH PATHOLOGIC NIPPLE DISCHARGE 乳头病理性溢液患者的乳腺造影、超声波和对比增强磁共振成像结果与病理学结果的比较
Pub Date : 2024-06-13 DOI: 10.31832/smj.1430107
S. Doğan, Emel Durmuş, Figen Öztürk
Objective: The purpose of this study was to evaluate the lesion detection rates of imaging methods by comparing galactography, ultrasonography(US) and contrast enhanced-magnetic resonance imaging(CE-MRI) findings with pathology results in patients with pathologic nipple discharge(PND). Materials and Methods: Fifty-two female patients with PND were included the study. Radiologic imaging and pathology results of patients were evaluated retrospectively. The lesion detection rates of galactography, US and CE-MRI were evaluated. Galactography findings were evaluated according to modified Galactogram Image Classification System(GICS) and compared with the pathology results. Results: Galactography was applied in 48 patients. While in 45(93.8%) of 48 patients lesion that causes PND was found on galactography. All of the patients had breast US. In 48(92.3%) patients, causing lesion was found on US. CE-MRI was performed in 33 of 52 patients, and lesion was found in 30 patients(90.9%). Lesion detection rates of galactography, US and CE-MRI findings were similar. Pathology results of 48 patients(92.3%) were benign, and the results of 3 patients(5.8%) were malignant. The result of 1 patient(2%), there was no lesion on pathologic examination. The sensitivity of galactography, US and CE-MRI were 93.6%, 92.2% and 90.6%, respectively. In the double and triple combinations of imaging methods regarding the lesion detection, sensitivity was found as 100%. There was no significant relationship between modified GICS scores and pathology results. Conclusion: The lesion detection rates of galactography, US, and CE-MRI were similar. When imaging methods are used in double and triple combinations, lesion detection rates could be increase.
研究目的本研究的目的是通过比较乳头病理性溢液(PND)患者的乳腺造影、超声波造影(US)和对比增强磁共振成像(CE-MRI)结果与病理学结果,评估影像学方法的病变检出率。材料与方法:研究对象包括 52 名女性 PND 患者。对患者的放射成像和病理结果进行回顾性评估。评估乳腺造影、US 和 CE-MRI 的病变检出率。根据改良的乳腺造影图像分类系统(GICS)对乳腺造影结果进行评估,并与病理结果进行比较。结果:48例患者进行了乳腺造影。48例患者中有45例(93.8%)在乳腺造影中发现了导致PND的病变。所有患者都进行了乳腺 US 检查。在 48 名患者(92.3%)中,通过 US 发现了导致 PND 的病灶。52 例患者中有 33 例进行了 CE-MRI 检查,其中 30 例(90.9%)发现了病灶。乳腺造影、超声波和 CE-MRI 发现病变的比率相似。48 名患者(92.3%)的病理结果为良性,3 名患者(5.8%)为恶性。1例患者(2%)的病理检查结果为无病变。乳腺造影、US 和 CE-MRI 的灵敏度分别为 93.6%、92.2% 和 90.6%。在病变检测方面,双联和三联成像方法的灵敏度为 100%。修改后的 GICS 评分与病理结果无明显关系。结论半乳成像、US 和 CE-MRI 的病变检出率相似。当成像方法被用于双重或三重组合时,病变检出率会提高。
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引用次数: 0
Insights into Myelin Oligodendrocyte Glycoprotein Associated Disease (MOGAD): Prevalence, Clinical Manifestations, and Treatment Responses in a Four-Year Retrospective Cohort Study 对髓鞘少突胶质细胞糖蛋白相关疾病(MOGAD)的认识:四年回顾性队列研究中的患病率、临床表现和治疗反应
Pub Date : 2024-05-08 DOI: 10.31832/smj.1438799
Abdulkadir Tunç, Alihan Abdullah Akbaş, Ömer Elçi, Beyzanur Bozkurt, Vasfiye Sezer
Introduction: This study aims to delineate the prevalence, clinical characteristics, diagnostic findings, and treatment outcomes of Myelin Oligodendrocyte Glycoprotein Associated Disease (MOGAD) in a cohort over four years, providing a basis for improved diagnostic criteria and therapeutic strategies. Materials and Methods: In a retrospective cohort study at a tertiary care center, we analyzed medical records of 90 patients presenting with CNS demyelinating symptoms, focusing on those diagnosed with MOGAD based on the International MOGAD Panel criteria. Data on clinical presentation, serum Anti-MOG antibody testing, MRI, VEP scans, CSF analysis, and treatment outcomes were evaluated. Results: Among the cohort of 90 patients, 7 patients were identified with positive Anti-MOG antibodies, indicating a prevalence of 7.8%. Clinical manifestations varied widely, including optic neuritis, myelitis, and cerebral cortical encephalitis. Diagnostic findings highlighted the absence of oligoclonal bands in CSF analysis and diverse MRI lesions. Most patients responded well to immunosuppressive treatments, though relapses occurred in two cases. The study underscores the heterogeneity of MOGAD presentations and the importance of personalized treatment approaches. Conclusion: Our findings contribute to the growing understanding of MOGAD, emphasizing its distinct clinical and diagnostic features compared to other CNS demyelinating disorders. The study advocates for the integration of MOG antibody testing in clinical practice to enhance diagnostic accuracy and patient outcomes. Future research should aim at longitudinal and multicentric studies to validate our findings and further refine MOGAD management strategies.
简介本研究的目的是在四年多的时间里对髓鞘少突胶质细胞糖蛋白相关疾病(MOGAD)的患病率、临床特征、诊断结果和治疗效果进行队列分析,为改进诊断标准和治疗策略提供依据。材料与方法:我们在一家三级医疗中心进行了一项回顾性队列研究,分析了 90 名出现中枢神经系统脱髓鞘症状的患者的病历,重点分析了根据国际 MOGAD 专家小组标准确诊为 MOGAD 的患者。我们评估了临床表现、血清抗 MOG 抗体检测、核磁共振成像、VEP 扫描、脑脊液分析和治疗结果等方面的数据。结果:在 90 名患者中,有 7 名患者的抗 MOG 抗体呈阳性,患病率为 7.8%。临床表现差异很大,包括视神经炎、脊髓炎和大脑皮质脑炎。诊断结果表明,脑脊液分析中没有寡克隆带,核磁共振成像病变也多种多样。大多数患者对免疫抑制治疗反应良好,但有两例复发。这项研究强调了 MOGAD 表现的异质性和个性化治疗方法的重要性。结论:我们的研究结果有助于加深人们对 MOGAD 的了解,强调了它与其他中枢神经系统脱髓鞘疾病相比独特的临床和诊断特征。该研究提倡将 MOG 抗体检测纳入临床实践,以提高诊断准确性和患者预后。未来的研究应以纵向和多中心研究为目标,以验证我们的发现并进一步完善 MOGAD 的管理策略。
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引用次数: 0
Psikiyatrik Tanı Alan Çocuk ve Ergenlerin Annelerinin Kaygı-Depresyon ve Suçluluk-Utanç Düzeylerinin Çocuğun Tanısı ile İlişkisi 被诊断患有精神病的儿童和青少年的母亲的焦虑-抑郁和内疚-羞愧水平与儿童诊断之间的关系
Pub Date : 2024-04-01 DOI: 10.31832/smj.1398723
Esin Cerit, Dılsad Miniksar
Amaç: Araştırmada, psikiyatrik tanısı olan çocuk ve ergenlerin annelerinin depresyon, kaygı ve suçluluk -utanç düzeylerinin çocuğun tıbbi tanısı ile ilişkisinin belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: Araştırma kesitsel desende, ilişki arayıcı bir çalışmadır. 15.10.2021-15.02.2022 tarihleri arasında ***Üniversitesi Sağlık Uygulama ve Araştırma Merkezi, Çocuk ve Ergen Psikiyatrisi Polikliniğine başvuran 92 hastanın annesi üzerinde yapılmıştır. Veriler, Kişisel Bilgi Formu, Beck Depresyon Envanteri, Beck Anksiyete Ölçeği, Suçluluk Utanç Ölçeği ile toplanmıştır. Çalışma verileri değerlendirilirken kategorik değişkenler için frekans dağılımı (sayı, yüzde), sayısal değişkenler için tanımlayıcı istatistikler (ortalama, standart sapma, minimum, maksimum) verilmiştir. Bağımsız Örneklem t Testi, Tek Yönlü Varyans Analizi, Mann Whitney U testi, Pearson Korelasyon Analizi ve basit doğrusal regresyon analizi verilerin analizinde kullanılmıştır. Bulgular: Annelerin çocuklarının psikiyatrik tanısına göre BDÖ ve BAÖ puan ortalamaları arasında istatistiksel olarak anlamlı farklılık olduğu saptanmıştır (p
研究目的本研究旨在确定被诊断患有精神疾病的儿童和青少年的母亲的抑郁、焦虑和内疚羞愧程度与孩子的医学诊断之间的关系。材料和方法:本研究是一项横断面相关研究。研究在 2021 年 10 月 15 日至 2022 年 2 月 2 日期间进行,对象是向***大学卫生实践与研究中心儿童和青少年精神病门诊申请就诊的 92 名患者的母亲。通过个人信息表、贝克抑郁量表、贝克焦虑量表和内疚羞愧量表收集数据。在评估研究数据时,对分类变量进行了频率分布(数量、百分比),对数字变量进行了描述性统计(平均值、标准差、最小值、最大值)。数据分析采用了独立样本 t 检验、单向方差分析、曼-惠特尼 U 检验、皮尔逊相关分析和简单线性回归分析。结果结果发现,母亲根据其子女的精神病诊断结果进行的平均评分之间存在显著的统计学差异(p
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引用次数: 0
Effectiveness Of Platelet Markers In Estimating The Amount Of Intraoperative Bleeding In Vertebra Surgery 血小板标记物在估计椎体手术术中出血量中的有效性
Pub Date : 2024-03-12 DOI: 10.31832/smj.1421647
Seliman Çeti̇nbulut, Onur Palabıyık, H. Kocayiğit, Ayça TAŞ TUNA, Davut Ceylan
AIMS: One of the most important steps in perioperative bleeding management is the predetermination of the patient at risk. Even if there is no hemostatic abnormality in vertebral surgery, which is a major surgery, severe bleeding can be encountered and many perioperative blood transfusions might be required. To date, there are no studies in the literature examining platelet markers in terms of predictivity in intraoperative bleeding during vertebral surgeries. In this study; we investigated the effectiveness of preoperative mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), mean platelet volume lymphocyte count ratio (MPVLR), and platelet count to lymphocyte count ratio (PLR) values in predicting the amount of intraoperative bleeding in patients who will undergo vertebral surgery. METHODS: After the approval from the ethics committee, patients who were planned for vertebral surgery by the neurosurgeon were identified. Patient demographic data such as gender, age, ASA score and body mass index (BMI), MPV, PDW, PCT, MPVLR, and PLR values were recorded. Total surgery time, the number of vertebral transpedicular screwing, and laminectomy levels performed as surgical procedures were recorded. The amount of intraoperative bleeding was determined by calculating the amount of blood accumulated in the aspirator and the amount of blood collected by the sponge during surgery. RESULTS: Of the 63 patients included in the study, 60.3% (n=38) were female and 39.7% (n=25) were male. The mean age of the patients was 54.7 ± 11 years and the mean BMI was 29.6 ± 4.6. No correlation was found between the amount of bleeding and gender, age, MPV, PDW, PCT, MPVLR, or PLR values. A significantly high correlation was found between amount of bleeding and BMI, duration of surgery, and the number of transpedicular screwing segments. CONCLUSION: Platelet markers do not appear to have an effect on the amount of bleeding. However, as the BMI increases, the duration of surgery prolongs and the number of transpedicular screw segments increases for which the amount of bleeding increases.
目的:围手术期出血处理最重要的步骤之一是预先确定高危患者。椎体手术是一项大手术,即使没有止血异常,也可能出现严重出血,围手术期可能需要多次输血。迄今为止,还没有文献研究血小板标记物对椎体手术术中出血的预测性。在本研究中,我们调查了术前平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板比容(PCT)、平均血小板体积淋巴细胞计数比值(MPVLR)和血小板计数与淋巴细胞计数比值(PLR)在预测椎体手术患者术中出血量方面的有效性。方法:经伦理委员会批准后,确定了计划由神经外科医生进行脊椎手术的患者。记录患者的人口统计学数据,如性别、年龄、ASA 评分和体重指数(BMI)、MPV、PDW、PCT、MPVLR 和 PLR 值。记录手术总时间、椎体经关节螺钉拧入数和椎板切除术层数。术中出血量通过计算吸血器中的积血量和手术中海绵收集的血量来确定。结果:在纳入研究的 63 名患者中,女性占 60.3%(38 人),男性占 39.7%(25 人)。患者的平均年龄为 54.7 ± 11 岁,平均体重指数为 29.6 ± 4.6。出血量与性别、年龄、MPV、PDW、PCT、MPVLR 或 PLR 值之间没有相关性。出血量与体重指数(BMI)、手术时间和经关节螺钉节段数之间存在明显的高度相关性。结论:血小板标记物似乎对出血量没有影响。然而,随着体重指数(BMI)的增加,手术时间延长,经关节螺钉节段数增加,出血量也随之增加。
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引用次数: 0
Percutaneous Endoscopic Gastrostomy Experience: Early and Late Complications 经皮内镜胃造口术经验:早期和晚期并发症
Pub Date : 2024-03-12 DOI: 10.31832/smj.1388895
E. B. Özşenel, Guldan Kahveci, Zuhal Çalişkan, Sema UÇAK BASAT
Background This study retrospectively evaluated the early and late complications of patients who had a percutaneous endoscopic gastrostomy (PEG) tube placed, discussed complication frequency of different diseases and finally pointed on some advices to reduce complications. Methods The study was conducted with 99 patients who had a PEG tube placed in the endoscopy unit of a training and research hospital. Patients’ age, gender, diagnosis, types of early and late complications, and complication development rates were evaluated. Results Mean age of the patients was 70.42±16.75(18-94) years and 48.5% were male. Early complications occurred in 11.1%, of which 6.05% were bleeding at the entry site of the PEG tube, and 5.05% were peristomal infection. 39.4% of the patients had late complications, including tube dislodgement in 18%, infection in 8.1%, aspiration pneumonia in 7.1% and other complications in 6%. No complications were observed in 51.5% of the patients, and early or late complications were observed in 48.5% of the patients. 2% of the patients had both early and late complications. The incidence of late complications was significantly higher in patients with Alzheimer’s disease (p=0.027). Conclusion In the follow-up of patients who had a PEG tube placed in the previous six months, the most common early complication was bleeding in 6.05%, and the most common late complication was tube dislodgement in 18%. Despite its potential complications, the PEG tube is a safe method for long-term enteral feeding. Alzheimer patients are at risk for late complications more than other diseases.
背景 本研究回顾性评估了置入经皮内镜胃造瘘管(PEG)患者的早期和晚期并发症,讨论了不同疾病的并发症发生率,最后提出了一些减少并发症的建议。 方法 研究对象是在一家培训和研究医院内镜室植入 PEG 管的 99 名患者。对患者的年龄、性别、诊断、早期和晚期并发症类型以及并发症发生率进行了评估。 结果 患者的平均年龄为 70.42±16.75(18-94)岁,48.5% 为男性。早期并发症发生率为 11.1%,其中 6.05% 为 PEG 管入口处出血,5.05% 为瘘管周围感染。39.4% 的患者出现晚期并发症,其中 18% 的患者出现管子脱落,8.1% 的患者出现感染,7.1% 的患者出现吸入性肺炎,6% 的患者出现其他并发症。51.5%的患者未出现并发症,48.5%的患者出现早期或晚期并发症。2%的患者同时出现早期和晚期并发症。阿尔茨海默病患者的晚期并发症发生率明显更高(P=0.027)。 结论 在对过去六个月内放置过 PEG 管的患者进行的随访中,最常见的早期并发症是出血,占 6.05%,最常见的晚期并发症是管子脱落,占 18%。尽管存在潜在并发症,但 PEG 管仍是一种安全的长期肠内喂养方法。与其他疾病相比,老年痴呆症患者更容易出现晚期并发症。
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引用次数: 0
The Effect Of Proximal Femoral Nail End Position In The Femoral Canal On Clinical And Radiological Outcomes Of Intertrochanteric Fractures 股骨近端钉末端在股骨窦内的位置对转子间骨折临床和放射学结果的影响
Pub Date : 2024-03-07 DOI: 10.31832/smj.1350817
Mehmet Fevzi Çakmak, Levent Horoz
Amaç : İntertrokanterik femurkırıklarında intramedüller çivi tedavisi son yıllarda yaygın olarak kullanılmaktadır. İntertrokanterik kırıkların intramedüller tespitinden sonra mekanik komplikasyon oranları %2-13 arasındadır. Proksimal femoral çivi uygulamasının mekanik başarısızlığına ilişkin risk faktörleri arasında lag vidası konumu, uç-apeks mesafesi, redüksiyon kalitesi ve femur boynu/şaft açısı yer alır. Çalışmamız femoral çivi ucunun femoral kanaldaki konumunun mekanik başarısızlık oranlarına ve radyolojik parametrelere etkisini değerlendirmeyi amaçlamaktadır. Gereç ve Yöntem : Haziran 2019 ile Eylül 2022 tarihleri arasında intertrokanterik kırık nedeniyle proksimal femur çivisi uygulanan 118 hastanın verileri analiz edildi. Hastalar femur kanalındaki proksimal femoral çivi ucunun pozisyonuna göre üç gruba ayrıldı. Ameliyat sonrası ve takip radyografilerinde uç apeks mesafesi, femur boynu/şaft açısı, redüksiyon kalitesi, lag vida konumu, kaynama süresi ve komplikasyonlar değerlendirildi. Bulgular : Çalışmaya dahil edilen tüm hastalar değerlendirildiğinde 9 hastada femur boynundan sıyrıldığı görüldü. Medial grupta sıyrılma oranları anlamlı olarak daha yüksekti (n=7, p=0,003). FNSA açısından her üç grupta da birbirinden istatistiksel olarak anlamlı farklar mevcuttu (
目的 :近年来,髓内钉治疗股骨转子间骨折已得到广泛应用。股骨转子间骨折髓内固定后的机械并发症发生率为 2%-13%。股骨近端钉机械性失败的风险因素包括滞后螺钉位置、尖端-外端距离、还原质量和股骨颈/轴角度。我们的研究旨在评估股骨钉尖端在股骨管中的位置对机械失败率和放射学参数的影响。材料和方法 :分析了2019年6月至2022年9月期间接受股骨近端钉治疗转子间骨折的118例患者的数据。根据股骨近端钉尖在股骨管内的位置将患者分为三组。术后和随访X光片分析了钉尖顶点距离、股骨颈/轴角度、复位质量、滞后螺钉位置、结合时间和并发症。结果 :对所有参与研究的患者进行评估后发现,9 名患者的股骨颈被剥离。内侧组的剥离率明显更高(7 人,P=0.003)。三组患者的 FNSA (
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引用次数: 0
Comparison of the Damage Results of Bullet and Pellet Ammunition in Firearm Injuries Causing Bone Fractures in the Extremities 比较子弹和鹈鹕弹在枪伤造成四肢骨折中的破坏结果
Pub Date : 2024-03-06 DOI: 10.31832/smj.1399230
Ahmet Atilla Abdioğlu, Kemal Paksoy, Oğuzhan Aslan, Sercan Karadeni̇z, İsmail Yükünç, K. Öner
Objective The spectrum of firearm injuries (FI) is broad and challenging for physicians in terms of diagnosis and treatment. The bullets and pellet ammunition used in FI exhibit different ballistic patterns and cause quite different damage to the body. The aim of this study was to compare the outcomes of bullet and pellet injuries causing bone fractures in the extremities. Methods The files of patients who were injured in their extremities due to civilian FI between 2016 and 2020 and who were followed up by the orthopedic clinic due to bone fractures were retrospectively analyzed. Age, gender, injured extremity, presence of infection, presence of vascular injury, presence of nerve injury, total number of operations, length of hospital stay and permanent sequelae were evaluated. Cases with missing files were excluded from the study. Evaluation criteria were compared under two main headings for bullet and pellet ammunition types. Results There were a total of 40 cases with a mean age of 43.5 years. The mean follow-up period was 41.5(24-61) months. 39 of the cases were male and 1 was female. There were 28 bullet injuries and 12 pellet injuries. Thirty-two of the cases were lower extremity injuries and 8 were upper extremity injuries. There were significant differences between ammunition type and number of operations (p=0.032).The length of hospital stay was significantly higher in the pellet group (p=0.024, p=0.024. Overall, 12.5% infection, 10% vascular damage, 17.5% nerve damage and 30% permanent sequelae occurred as a result of treatments. There were no significant differences between the groups in terms of infection, vascular injury, nerve injury and permanent sequelae. Conclusion When comparing the clinical outcomes of bullets and pellet ammunition, there were many differences in the severity of the injury and the treatment process.
目标 枪械伤害(FI)的范围很广,对医生的诊断和治疗具有挑战性。火器伤中使用的子弹和弹丸表现出不同的弹道模式,对人体造成的伤害也大相径庭。本研究的目的是比较子弹和霰弹造成四肢骨折的结果。方法 回顾性分析了 2016 年至 2020 年期间因民用射弹造成四肢受伤并因骨折而在骨科诊所接受随访的患者档案。对年龄、性别、受伤肢体、有无感染、有无血管损伤、有无神经损伤、手术总数、住院时间和永久性后遗症进行了评估。研究排除了档案缺失的病例。对子弹和弹丸两种类型的评估标准进行了比较。结果 共有 40 个病例,平均年龄为 43.5 岁。平均随访时间为 41.5(24-61)个月。其中 39 例为男性,1 例为女性。子弹伤 28 例,弹丸伤 12 例。其中 32 例为下肢受伤,8 例为上肢受伤。子弹类型和手术次数之间存在明显差异(P=0.032)。弹丸组的住院时间明显较长(P=0.024,P=0.024。总体而言,12.5%的治疗导致感染,10%导致血管损伤,17.5%导致神经损伤,30%导致永久性后遗症。各组在感染、血管损伤、神经损伤和永久性后遗症方面无明显差异。结论 在比较子弹和弹丸弹药的临床结果时,损伤的严重程度和治疗过程存在许多差异。
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引用次数: 0
Türkiye'de Cerrahi Alanına Yönelik Hasta Şikayetleri: Dijital Platformdaki Yorumların Analizi 土耳其患者对手术的投诉:分析数字平台上的评论
Pub Date : 2024-02-12 DOI: 10.31832/smj.1402643
Adem Şentürk, Mevlüt Yordanagi̇l
Aim: The purpose of the research is to examine patient complaints made on the internet site "sikayetvar" regarding the field of surgery in Turkey. The study also aims to identify common themes in patient complaints about the surgery department, better define the patient population making complaints, and systematically examine the reasons for complaints. Materials and Methods: In the research designed as a retrospective, the complaints made to the complaintvar.com website were examined using the content analysis method, which is one of the qualitative research methods. In the research, 359 posts on the internet about the general surgery department in Turkey, made on the complaintvar.com site, between January 1, 2023 and November 1, 2023, were examined. Complaints made; They are classified according to gender, whether they are public or private hospitals, whether they are inpatients, outpatients or emergency patients, type of surgical procedure, whether only surgical intervention is performed, whether they are related to other departments, the number of views of the complaint and the subject of the complaint. Results: In the study, 335 (93.3%) of the complaints were related to the procedures performed in general surgery. It was observed that they received a response to 74 (20.6%) of the complaints. It was observed that the complaints from all outpatient clinic patients were significantly higher than the complaints from ward, surgery and endoscopy patients (p
研究目的:本研究的目的是检查患者在互联网网站 "sikayetvar "上提出的有关土耳其外科领域的投诉。研究还旨在确定患者对外科部门投诉的共同主题,更好地界定投诉的患者群体,并系统地研究投诉的原因。材料和方法:在这项回顾性研究中,采用定性研究方法之一的内容分析法,对投诉到 complaintvar.com 网站的投诉进行了研究。在研究中,对 2023 年 1 月 1 日至 2023 年 11 月 1 日期间在 complaintvar.com 网站上发布的有关土耳其普外科的 359 条帖子进行了审查。投诉;根据性别、公立医院还是私立医院、住院病人、门诊病人还是急诊病人、手术类型、是否只进行外科干预、是否与其他科室有关、投诉的浏览次数和投诉对象进行分类。研究结果研究中,有 335 份(93.3%)投诉与普外科的手术有关。据观察,他们收到了 74 份(20.6%)投诉的回复。据观察,所有门诊病人的投诉明显高于病房、手术室和内窥镜检查病人的投诉(p
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引用次数: 0
Türkiye'de Cerrahi Alanına Yönelik Hasta Şikayetleri: Dijital Platformdaki Yorumların Analizi 土耳其患者对手术的投诉:分析数字平台上的评论
Pub Date : 2024-02-12 DOI: 10.31832/smj.1402643
Adem Şentürk, Mevlüt Yordanagi̇l
Aim: The purpose of the research is to examine patient complaints made on the internet site "sikayetvar" regarding the field of surgery in Turkey. The study also aims to identify common themes in patient complaints about the surgery department, better define the patient population making complaints, and systematically examine the reasons for complaints. Materials and Methods: In the research designed as a retrospective, the complaints made to the complaintvar.com website were examined using the content analysis method, which is one of the qualitative research methods. In the research, 359 posts on the internet about the general surgery department in Turkey, made on the complaintvar.com site, between January 1, 2023 and November 1, 2023, were examined. Complaints made; They are classified according to gender, whether they are public or private hospitals, whether they are inpatients, outpatients or emergency patients, type of surgical procedure, whether only surgical intervention is performed, whether they are related to other departments, the number of views of the complaint and the subject of the complaint. Results: In the study, 335 (93.3%) of the complaints were related to the procedures performed in general surgery. It was observed that they received a response to 74 (20.6%) of the complaints. It was observed that the complaints from all outpatient clinic patients were significantly higher than the complaints from ward, surgery and endoscopy patients (p
研究目的:本研究的目的是检查患者在互联网网站 "sikayetvar "上提出的有关土耳其外科领域的投诉。研究还旨在确定患者对外科部门投诉的共同主题,更好地界定投诉的患者群体,并系统地研究投诉的原因。材料和方法:在这项回顾性研究中,采用定性研究方法之一的内容分析法,对投诉到 complaintvar.com 网站的投诉进行了研究。在研究中,对 2023 年 1 月 1 日至 2023 年 11 月 1 日期间在 complaintvar.com 网站上发布的有关土耳其普外科的 359 条帖子进行了审查。投诉;根据性别、公立医院还是私立医院、住院病人、门诊病人还是急诊病人、手术类型、是否只进行外科干预、是否与其他科室有关、投诉的浏览次数和投诉对象进行分类。研究结果研究中,有 335 份(93.3%)投诉与普外科的手术有关。据观察,他们收到了 74 份(20.6%)投诉的回复。据观察,所有门诊病人的投诉明显高于病房、手术室和内窥镜检查病人的投诉(p
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引用次数: 0
Penı̇sı̇lı̇n ile Oluşturulan Deneysel Epilepsi Modelinde Seftrı̇aksonun Etkı̇sı̇: Elektrofı̇zyolojı̇k Bı̇r Çalışma 头孢曲松对青霉素诱发的实验性癫痫模型的影响:电生理学研究
Pub Date : 2024-02-08 DOI: 10.31832/smj.1369398
Zeynep KASAP ACUNGİL, Şeyma Özsoy
Introduction: Epilepsy is a set of chronic neurological disorders characterized by seizures associated with abnormal and uncontrolled neuronal activity of the brain. Glutamate is the main excitatory neurotransmitter in the central nervous system. Excitatory amino acid transporter-2 (EAAT2), one of the major glutamate transporters, is responsible for total glutamate intake. Ceftriaxone is a β-lactam antibiotic that increases EAAT-2 expression and functional activity. This study aims to investigate the effects of ceftriaxone on penicillin-induced epileptiform activity by using electrocorticography (ECoG) in anesthetized rats. Materials and Methods: In this study, 35 Wistar male rats were used. The rats were divided into five groups of 7. In group 1, 2.5 μL 500 IU of penicillin intracranially (i.c.) and 1 ml saline solution and intraperitoneally (i.p.) were given, respectively. In group 2, 200 mg/kg, i.p. of ceftriaxone was administered 30 minutes after penicillin. In group 3, 400 mg/kg of ceftriaxone was administered i.p. 30 minutes after penicillin. 500 mg/kg of sodium valproate was administered i.p. following 30 minutes of penicillin in group 4. In group 5, 400 mg/kg, i.p. of ceftriaxone and 500 mg/kg, i.p. of sodium valproate were administered 30 minutes after penicillin. The rats were placed in a stereotaxic device after the procedure, and electrocorticogram recordings were captured for 180 minutes. Results: The acute treatment of ceftriaxone reduced spike-wave frequency and spike-wave amplitude of penicillin-induced epileptiform activity in the rats. Conclusion: These findings suggest that acute ceftriaxone had an anticonvulsant effect on penicillin-induced focal onset epileptic activity. Ceftriaxone may has an anti-epileptogenic potential.
导言:癫痫是一组慢性神经系统疾病,其特点是癫痫发作与大脑神经元活动异常和失控有关。谷氨酸是中枢神经系统中主要的兴奋性神经递质。兴奋性氨基酸转运体-2(EAAT2)是谷氨酸的主要转运体之一,负责谷氨酸的总摄入量。头孢曲松是一种β-内酰胺类抗生素,可增加EAAT-2的表达和功能活性。本研究旨在利用皮层电图(ECoG)研究头孢曲松对青霉素诱导的癫痫样活动的影响。材料和方法:本研究使用了 35 只 Wistar 雄性大鼠。在第 1 组中,分别给予 2.5 μL 500 IU 青霉素颅内注射(i.c.)和 1 ml 生理盐水溶液及腹腔注射(i.p.)。第 2 组在注射青霉素 30 分钟后静脉注射头孢曲松 200 毫克/千克。第 3 组在青霉素注射 30 分钟后静脉注射 400 毫克/千克头孢曲松。第 4 组在注射青霉素 30 分钟后,静脉注射 500 毫克/千克丙戊酸钠。 第 5 组在注射青霉素 30 分钟后,静脉注射 400 毫克/千克头孢曲松和 500 毫克/千克丙戊酸钠。手术后,将大鼠置于立体定向装置中,并进行 180 分钟的皮层电图记录。结果头孢曲松的急性治疗降低了青霉素诱发大鼠癫痫样活动的尖峰波频率和尖峰波振幅。结论这些研究结果表明,急性头孢曲松对青霉素诱发的局灶性癫痫活动有抗惊厥作用。头孢曲松可能具有抗致痫潜能。
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引用次数: 0
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Sakarya Medical Journal
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