非手术牙周治疗对类风湿关节炎严重程度的影响

E. Atabati
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摘要

背景:牙周病伴牙槽骨变性和牙齿脱落见于许多人,包括类风湿性关节炎患者。目的探讨非手术牙周治疗对类风湿关节炎严重程度的影响。方法:对60例同时患有关节炎和轻中度牙周炎的患者进行随机对照临床试验。患者分为三组,每组20人(C组进行牙齿清洁和抗生素治疗,B组只进行牙齿清洁,A组为对照组)。在研究开始时,所有三组都填写了DAS28问卷。治疗结束改善后,于第45天和第90天对患者进行类风湿关节炎改善指标的检查。最后用SPSS18对数据进行分析。结果:ESR、DAS28、CRP、RF在不同时间段的降低率均以洁牙干预+抗生素组最高,其次为洁牙组。对照组降低幅度最小。洁牙组和洁牙+抗生素组RF、CRP、DAS28指标在不同时间段差异均有统计学意义(P<0.05)。结论:在不考虑治疗药物的情况下,非手术牙周治疗及RA指标对本病的治疗均有积极作用。
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The Effect of non-Surgical Periodontal Treatments on the Severity of Arthritis Rheumatoid
Background: periodontal disease with alveoli bone degeneration and losing teeth is seen in many people, including those with arthritis rheumatoid. Objective This study aims to evaluate the effect of non-surgical periodontal treatments on the severity of arthritis rheumatoid. Methods: this randomized control clinical trial was conducted on 60 patients who concurrently had arthritis and mild to moderate periodontitis. Patients divided into three groups of 20 subjects (group C had tooth cleaning and antibiotic therapy, group B had only tooth cleaning and group A was control). DAS28 questionnaire was filled out for all three groups at the beginning of the study. After ending the treatment and improvement, patients were examined in days 45 and 90 in terms of improvement indicators for arthritis rheumatoid. Data were finally analyzed by SPSS18. Results: the highest reduction rate of ESR, DAS28, CRP and RF was in different time periods in tooth cleaning intervention +antibiotic group and then, teeth cleaning group. The lowest reduction was seen in control group. RF, CRP and DAS28 indices showed significant differences in different time periods in tooth cleaning group and tooth cleaning+ antibiotic group (P<0.05). Conclusion: non-surgery periodontal treatment and RA indices, without considering the medicines used for treatment, had positive effect on the treatment of this disease.
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