北美接触性皮炎小组1998年至2000年的斑贴试验结果。

J. Marks, Donald V. Belsito, V. Deleo, J. Fowler, Anthony F. Franswa, H. Maibach, C. Mathias, M. Pratt, R. Rietschel, E. F. Sherertz, F. Storrs, James S. Taylor
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引用次数: 164

摘要

背景:斑贴试验是评估疑似过敏性接触性皮炎患者最有价值的诊断工具。目的:本研究报告了北美接触性皮炎小组从1998年7月1日至2000年12月31日的斑贴试验结果。方法采用标准化的补丁测试技术,对患者进行相同系列的过敏原筛查。这些患者的数据被记录在一个标准的计算机输入表格上并进行分析。结果在5800多例患者中检测了50种过敏原。脒胺、二苯甲酮-3和碘丙基丁基氨基甲酸酯是新的过敏原。阳性反应频率前10位的过敏原与我们1996年至1998年的研究期间相同。过敏镍反应的发生率持续上升,在所有测试物质中领先16.2%。结论:我们的研究结果强调需要一个比在美国销售的T.R.U.E. TEST中发现的更全面的诊断过敏原组。
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North American Contact Dermatitis Group patch-test results, 1998 to 2000.
BACKGROUND Patch testing is the most worthwhile diagnostic tool for the evaluation of patients with suspected allergic contact dermatitis. OBJECTIVE This study reports patch-testing results from July 1, 1998, to December 31, 2000, by the North American Contact Dermatitis Group. METHODS Patients were tested with the same screening series of allergens, using a standardized patch-testing technique. The data from these patients were recorded on a standard computer entry form and analyzed. RESULTS Fifty allergens were tested on over 5,800 patients. Amidoamine, benzophenone-3, and iodopropynyl butylcarbamate were the new allergens. The top 10 allergens in frequency of positive reactions were identical to those of our 1996-to 1998-study period. The incidence of allergic nickel reactions continues to go up, leading all the test substances by 16.2%. CONCLUSION Our findings reinforce the need for a more comprehensive group of diagnostic allergens than is found in the T.R.U.E. TEST, which is sold in the United States.
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