肌萎缩侧索硬化症的认知障碍

M. Kutlubaev, D. K. Areprintceva, E. V. Pervushina, L. Brylev
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引用次数: 0

摘要

超过一半的肌萎缩侧索硬化症(ALS)患者存在认知障碍(CD),但很少达到痴呆的程度。目前,ALS的分类已经提出取决于是否存在认知和/或行为障碍。肌萎缩性侧索硬化症的CD表现为语言流利障碍、各种失语障碍、调节功能障碍、社会认知功能障碍和言语记忆障碍。诊断上最敏感的是一些特殊的量表,比如针对ALS的爱丁堡认知和行为障碍筛查量表。肌萎缩性侧索硬化症患者的CD对疾病的预后和患者及其家属的生活质量有负面影响。这个问题需要进一步研究。
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Cognitive disorders in amyotrophic lateral sclerosis
Cognitive disorders (CD) are observed in more than half of patients with amyotrophic lateral sclerosis (ALS), but rarely reach the degree of dementia. Currently, a classification of ALS has been proposed depending on the presence of cognitive and/or behavioral disorders. CD in ALS can be represented by speech fluency disorders, various aphasic disorders, disorders of regulatory functions, social cognitive functions, and verbal memory. The most diagnostically sensitive are special scales, such as the Edinburgh Cognitive and Behavioral Impairment Screening Scale for ALS. CD in ALS have a negative impact on the outcome of the disease and the quality of life of patients and their families. This issue requires further study.
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