慢性心力衰竭患者ii型右心室舒张功能不全风险评估评分量表

O. M. Zherko, E. I. Shkrebneva, P. Novikov, A. Babenka, V. Gorbachev, M. Kosova, A. Kabanava, N. A. Averchankava
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Exclusion criteria: primary mitral regurgitation, mitral stenosis, mitral valve repair or replacement, congenital heart defects, acute and chronic diseases of the lungs and kidneys. Results. The sum of points>52 obtained using a scoring scale that includes scientifically based ultrasound criteria for global cardiac remodelling: RV early diastolic filling index E/eʹ >4.08 (sensitivity (S) 81.1%, specificity (Sp) 56.9%) - 15 points, the amplitude of the systolic displacement of the lateral part of the tricuspid annulus in systole to the apex (TAPSE) ≤20 mm (S 74.1%, Sp 83.3%) - 49 points, pulmonary artery systolic pressure ˃32.6 mm Hg (S 85.2%, Sp 79.5%) - 31 points, indicates a high risk of detecting RV DD of type II in CHF (AUC 0.99, S 93.9%, Sp 100.0%). The reproducibility of the results is shown in an independent examination sample of patients with CHF with preserved left ventricular ejection fraction. 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引用次数: 0

摘要

Odjectives。建立慢性心力衰竭(CHF)患者ⅱ型右心室(RV)舒张功能障碍(DD)检测风险的评分量表。材料和方法。2017-2018年,在明斯克“第一城市临床医院”医疗机构对247名40-86岁的患者进行了临床和仪器检查,2019-2020年,129名39-84岁的患者在国立机构“明斯克外科、移植和血液学科学和实践中心”进行了检查。研究纳入标准:窦性心律、原发性动脉高血压(AH)、慢性缺血性心脏病(IHD)、CHF,知情自愿同意参加研究的患者。排除标准:原发性二尖瓣返流、二尖瓣狭窄、二尖瓣修复或置换术、先天性心脏缺陷、肺和肾脏急慢性疾病。结果。使用评分量表(包括基于科学的整体心脏重构超声标准)获得的>52分的总和:RV舒张早期充盈指数E/ E′>4.08(敏感性(S) 81.1%,特异性(Sp) 56.9%) 15分,收缩期三尖瓣环外侧收缩位移幅值(TAPSE)≤20 mm (S 74.1%, Sp 83.3%) - 49分,肺动脉收缩压≤32.6 mm Hg (S 85.2%, Sp 79.5%) - 31分,提示诊断CHF型RV DD的风险较高(AUC 0.99, S 93.9%, Sp 100.0%)。在保留左心室射血分数的CHF患者的独立检查样本中显示了结果的重复性。(AUC 0.99, S 90.0%, Sp 100%, +PV 100.0%, - PV 34.5%,临界值>52)。结论。使用该量表时,评分> 52,建议对合并CHF、原发性AH、慢性IHD的患者进行全面有针对性的心脏重构评估,以确定II型RV DD。
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SCORING SCALE FOR ASSESSING THE RISK OF DETECTING RIGHT VENTRICLE DIASTOLIC DYSFUNCTION OF TYPE II IN CHRONIC HEART FAILURE
Odjectives. To develop a scoring scale for assessing the risk of detecting right ventricle (RV) diastolic dysfunction (DD) of type II in chronic heart failure (CHF). Material and methods. In 2017-2018, a clinical and instrumental examination of 247 patients aged 40-86 years was performed on the basis of Health Care Institution «The 1st City Clinical Hospital» in Minsk, in 2019-2020, 129 patients at the age of 39-84 years were examined in the State Institution «Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology». Study inclusion criteria: sinus rhythm, essential arterial hypertension (AH), chronic ischemic heart disease (IHD), CHF, informed voluntary consent of the patient to participate in the study. Exclusion criteria: primary mitral regurgitation, mitral stenosis, mitral valve repair or replacement, congenital heart defects, acute and chronic diseases of the lungs and kidneys. Results. The sum of points>52 obtained using a scoring scale that includes scientifically based ultrasound criteria for global cardiac remodelling: RV early diastolic filling index E/eʹ >4.08 (sensitivity (S) 81.1%, specificity (Sp) 56.9%) - 15 points, the amplitude of the systolic displacement of the lateral part of the tricuspid annulus in systole to the apex (TAPSE) ≤20 mm (S 74.1%, Sp 83.3%) - 49 points, pulmonary artery systolic pressure ˃32.6 mm Hg (S 85.2%, Sp 79.5%) - 31 points, indicates a high risk of detecting RV DD of type II in CHF (AUC 0.99, S 93.9%, Sp 100.0%). The reproducibility of the results is shown in an independent examination sample of patients with CHF with preserved left ventricular ejection fraction. (AUC 0.99, S 90.0%, Sp 100%, +PV 100.0%, - PV 34.5% with a cut-off threshold >52). Conclusions.When using the scale, the score is > 52, it is recommended to perform a comprehensive targeted assessment of global cardiac remodelling to determine RV DD of type II in a patient with CHF, complicating essential AH, chronic IHD.
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