评估燃煤电厂工人接触多环芳烃的癌症风险

Bin Li, Zhaolong Zhang, H. Fan, C. Zeng
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摘要

为了研究尿中1-OH-Py、3-OH-BaP浓度与人体多环芳烃暴露程度及途径的关系,我们于2011年收集了华中某燃煤电厂60名烤炉工人和60名未接触多环芳烃的普通人群24小时的空气、饮食和尿液样本。测定了空气和饮食样品中8种强致癌性多环芳烃的浓度,以及尿液中1-OH-Py和3-OH-BaP的浓度。通过对人体接触多环芳烃途径的研究,发现燃煤电厂工人的高致癌风险主要是通过呼吸污染的空气接触到多环芳烃,而通过饮食接触多环芳烃的程度与一般人群相似。为降低燃煤电厂工人患癌风险,应加强职业防护,改善工作环境。
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Assessing Cancer Risk of Coal-Fired Power Plant Workers Exposed to PAHs
To study the relationship between the concentration of urinary 1-OH-Py, 3-OH-BaP and the degree as well as the pathways of human exposure to PAHs, we collected 24-hour air, dietary and urine samples of 60 oven workers in a coal-fired power plant of Central China and 60 people in a general group not exposed to such PAHs in 2011. The concentrations of eight strong carcinogenic PAHs in air and dietary samples, and the concentrations of the urinary 1-OH-Py and 3-OH-BaP were determined. By studying the pathways of human exposure to PAHs, it is found that the main reason for coal-fired power plant workers' high cancer risk is the exposure to PAHs by breathing contaminated air, while the degree of exposure to PAHs through diet is similar to that of the general group. In order to reduce coal-fired power plant workers' cancer risk, occupational protection should be strengthened, and the working environment should be improved.
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