Retroperitoneal liposarcoma: an unusual case of weight gain despite weight loss measures

Retroperitoneal liposarcomas are a heterogenous group of mesenchymal tumors that have a wide spectrum of histological subtypes and vague clinical presentation. 1 They are locally invasive and the peak incidence is in the 5th decade. 2 They account for 0.1-0.2% of all solid tumors and 15% of all soft-tissue tumors. 2 Liposarcomas are usually large and occur most frequently in the lower extremities, in the retroperitoneal, perineal and mesenteric region. 2 In the retroperitoneum, they grow without symptoms due to the ability of the abdominal cavity to accommodate these slowly expanding masses. 2 We present the case of 72yr old male who presented to urology and oncology due to the diagnosis of igh grade Gleason 9 prostate adenocarcinoma and a history of Agent Orange exposure. In the process of his workup, he complained of feeling full and gaining weight gain despite his best efforts at dieting and weight loss. Due to his abdominal distention, a CT scan of the abdomen and pelvis was performed which demonstrated 2 large fat containing intra abdominal masses suspicious for liposarcoma.