Evaluation of serological indicators of the presence of antibodies to pathogens of natural focal infections in the population of the Rostov region in 2021

Objective: to analyze the results of blood sera comprehensive study of the local population of the RR, conducted in 2021 to assess the state of natural and zoonotic focus of CHF, WNF, ITBB, tularemia and risk of possible spread of Haemorrhagic Fever with Renal Syndrome (HFRS). Materials and methods: 424 blood serums obtained in 2021 from healthy donors living in 10 administrative territories of the Russian Federation were tested by enzyme immunoassay. Results: in 2021 the detection rates of specific antibodies in the studied areas were: WNF — 9,9 %, HFRS — 4,5 %, ITBB — 2,6 %, CHF — 0,7 %, tularemia — 22,6 %. When comparing the results obtained in 2020 and 2021, the difference in the proportions of seropositive samples is not statistically significant. Conclusions: the study of the immune layer to NFI in selected population groups confirms the circulation of pathogens in RR territory. The monitoring results demonstrate the extensive, mostly combined nosoareals of NFI of viral and bacterial etiology and the contact of the local population with them.