Issues of Vaccination of SARS-CoV-2 Infection in Chronic Liver Diseases

Vaccination of SARS-CoV-2 infection is an obvious and significant component of the fight against the COVID-19 pandemic. Vaccination of groups of patients with the weakened immunological response to the vaccine, such as patients with chronic liver diseases (CLD), is especially important. Due to constantly updated data, general practitioners may lose sight of the features of immunization of patients with CLD from the professional field of view. The purpose is to highlight current ideas on the immunization of patients with CLD of various etiologies, to consider possible risks of vaccination, to identify prospects for further research in this area. Conclusion. All patients with CLD, regardless of the etiology and stage of the disease, are recommended to be vaccinated against COVID-19, which reduces the risk of decompensation of both the main and concomitant chronic diseases, the onset of adverse outcomes and leads to the formation of collective immunity of the population