2021-2022年戈尔根市第五阿扎医院局麻白内障手术患者咪达唑仑、异丙酚和右美托咪定对血流动力学变化的影响

Seyede Mahrokh Alinaghimaddah, Mohammad Reza Akbari, Kazem Kazemnejad Tabrizi, Vahid Ownagh, Seyed Esmaeil Hatami
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摘要

白内障手术是一种常见的手术,特别是在老年人中,麻醉药物的选择对这类患者至关重要。本研究探讨了咪达唑仑、异丙酚和右美托咪定在局部麻醉下对白内障手术患者的镇静作用。方法:90例白内障患者(按照ASA标准)采用II级和III级麻醉行白内障手术。他们也被随机分为三组。第一组给予咪达唑仑,第二组给予异丙酚,第三组给予右美托咪定。术中及恢复期记录血压、动脉血氧饱和度、心率及并发症发生情况。数据分析采用SPSS软件(版本23),显著性水平为0.05。结果:三组患者动脉血氧饱和度(SpO2)水平变化差异无统计学意义(P>0.05);异丙酚组恢复时SpO2水平变化较小(P0.05),右美托咪定组恢复时SpO2水平变化较低(P>0.05)。三组患者手术及恢复期间心率差异无统计学意义(P>0.05)。结论:右美托咪定可能是高血压合并心动过速患者较好的镇静选择。
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Comparison of the Effects of Midazolam, Propofol, and Dexmede-tomidine on Hemodynamics Variation in Patients Undergoing Cataract Surgery under Local Anesthesia at 5th Azar Hospital in Gorgan in 2021-2022
Introduction: Cataract surgery is a common surgery, especially among the elderly, and the choice of anesthesia medications is critical in such patients. In this study, the effects of midazolam, propofol, and dexmedetomidine were investigated for sedation in patients undergoing cataract surgery under local anesthesia. Method: Ninety patients were included in this study and underwent cataract surgery using class II and III anesthesia (according to the ASA criteria). They were also randomly assigned to three groups. The first group received midazolam, the second group received propofol, and the third group received dexmedetomidine. During the surgery and recovery phase, blood pressure, arterial blood oxygen saturation, heart rate, and the occurrence of complications were recorded. Data were analyzed using the SPSS software (version 23) at a significance level of 0.05. Results: Alterations in arterial blood oxygen saturation (SpO2) levels were not significantly different among the three groups (P>0.05); however, there were fewer changes in SpO2 levels at recovery in the propofol group (P<0.05). Moreover, alterations in blood pressure did not differ significantly across the three groups during the surgery (P>0.05), whereas during the recovery, they were lower in the group receiving dexmedetomidine (P>0.05). Finally, Heart rates were not significantly different among the three groups during surgery and recovery (P>0.05). Conclusion: The results demonstrated that in patients with hypertension and tachycardia, dexmedetomidine may be a better choice for sedation.
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