脊髓肿瘤病变的组织形态学谱和趋势:单一机构40年回顾

A. Salami, Nwadiokwu John Ifeanyi, Iwuagwu Emmanuel Ifeanyi, Ajani Mustapha Akanji, Ayokunle James Balogun, OyemoladeAyofe Toyin, A. Augustine
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摘要

目的:与脑肿瘤相比,脊柱肿瘤的发病率要低得多。在我们的环境中,由于数据收集不良、少报以及可能缺乏向医疗机构的报告,关于脊柱肿瘤的研究很少。以前的研究报告髓外肿瘤在我们的环境中更为常见。本研究检查了非洲地区脊髓肿瘤的组织形态学谱,并将其与以前的观察结果进行比较,以确定几十年来的变化。方法从40年的医院记录中获取数据。这些包括患者的年龄、性别和所有肿瘤性脊柱病变的组织形态学资料。采用SPSS 20统计软件对数据进行分析。结果研究期间共发现94例。这些肿瘤在30岁到60岁之间更为常见。有轻微的男性优势,男女比例为1.2:1。脑膜瘤是研究期间最常见的肿瘤,这与之前的研究显示的伯基特淋巴瘤形成对比。数据还显示,在研究期间,病例数量稳步上升,这表明患者到医院就诊的人数增加,手术病例增多。结论:指数研究显示,与以往研究的数据相比,研究期间的患者人口统计学和组织学肿瘤类型有所不同。这可能是由于更好的认识和更好的诊断设施。
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Histomorphological Spectrum and Trend of Spinal Neoplastic Lesions: A Single Institutional 40-year review
OBJECTIVES Spinal tumours are known to be much less common compared to brain neoplasms. In our setting, due to poor data gathering, underreporting and probably lack of presentation to medical facilities, studies on spinal tumours are sparse. Previous studies had reported extramedullary tumours to be more common in our environment. This study examines the histomorphological spectrum of spinal tumours in an African setting, comparing it with previous observations to determine changes over the decades. METHODS Data was obtained from the hospital records of patients over a forty-year period. These include the patients’ age, gender and histomorphological data of all the neoplastic spinal lesions. The data was analysed using SPSS 20 statistical software. RESULTS Ninety four cases were seen during the study period. The tumours were more common between the third to the sixth decades of life. There was a slight male preponderance with a male to female ratio of 1.2:1. Meningiomas were the commonest tumours seen during the study period which is in contrast to previous studies that had shown Burkitt lymphoma. The data also showed a steady rise in the number of cases during the study period suggesting an increase in patients’ presenting to the hospital and more surgical cases. CONCLUSION The index study showed a difference in patients demographics and the histological tumour types seen over the study period compared to the data from previous studies. This is probably due to better awareness and better diagnostic facilities.
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