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Workplace experiences of diagnostic radiographers, on job satisfaction and staff retention in the public health sector in Lusaka District of Zambia 赞比亚卢萨卡区公共卫生部门放射诊断技师的工作场所经验、工作满意度和员工留用情况
Pub Date : 2024-03-30 DOI: 10.55320/mjz.50.4.454
M. Bwalya, Roshnee Sunder, F. Munsanje, O. Bwanga
Background: Zambia’s healthcare workforce is reportedly inadequate for the country’s healthcare needs. This stems from healthcare professionals, particularly radiographers, exiting the public health sector for non-governmental organizations or other countries with attractive conditions of service. This study is required to explore and describe the workplace experiences of public health sector radiographers in the province of Lusaka in Zambia and to examine how these experiences influence job satisfaction and staff retention. Methods: The study used a qualitative research design. Semi-structured interviews were conducted to collect data from 20 purposively selected public service radiographers, working in the Lusaka district of Zambia. Interviews were recorded, transcribed, and analysed by themes. Results: Five themes emerged: physical work environment, remunerations and rewards, staff workloads, leadership and supervision, and professional development. This study established that participants appreciate their physical work environment which constitutes modern and various imaging equipment.  However, the majority of the participants expressed dissatisfaction with their workplace experiences owing to inadequate workspaces, inadequate salaries, a lack of incentives and rewards, increased workloads and inflexible work schedules, unapproved leadership style, lack of performance recognition and support for continuing professional development. Conclusion: The study findings provided information on the deficiencies within public service radiographers’ work environment. To enhance job satisfaction and retention, the employer needs to address the challenges being experienced by the radiographers.   
背景:据报道,赞比亚的医疗保健队伍不足以满足该国的医疗保健需求。这是因为医疗保健专业人员,尤其是放射技师,离开了公共卫生部门,前往非政府组织或服务条件有吸引力的其他国家工作。本研究需要探讨和描述赞比亚卢萨卡省公共卫生部门放射技师的工作经历,并研究这些经历如何影响工作满意度和员工保留率。研究方法:本研究采用定性研究设计。对在赞比亚卢萨卡地区工作的 20 名公共服务放射技师进行了半结构化访谈,以收集数据。对访谈进行了记录、转录和主题分析。结果:出现了五个主题:实际工作环境、薪酬和奖励、员工工作量、领导和监督以及专业发展。这项研究表明,参与者非常欣赏由现代化和各种成像设备构成的物质工作环境。 然而,大多数参与者对工作场所的体验表示不满,原因是工作空间不足、工资不高、缺乏激励和奖励措施、工作量增加和工作时间安排不灵活、领导风格未经认可、缺乏绩效认可和对持续专业发展的支持。结论研究结果提供了有关公共服务放射技师工作环境缺陷的信息。为了提高工作满意度和留住人才,雇主需要解决放射技师所面临的挑战。
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引用次数: 0
Role Development and Extension for Radiographers in Computed Tomography: Literature Review Findings and their Application to Zimbabwe 计算机断层扫描中放射技师的角色发展与扩展:文献综述结果及其在津巴布韦的应用
Pub Date : 2024-03-30 DOI: 10.55320/mjz.50.4.449
B. Chinene, O. Bwanga
Computed Tomography (CT) technology has evolved into a vital diagnostic tool in modern medical practice, leading to the development and extension of the CT radiographer's role. While some countries have made progress in developing and extending radiographers' roles in CT, resource-constrained settings like Zimbabwe have been slower to implement these changes. The purpose of this review is to inform role changes for radiographers in Zimbabwe and similar settings by reviewing the literature on role development and extension for radiographers in CT. The review explores the concepts of role development and extension, emphasizing the necessity for changes in radiographers' roles in CT due to factors such as radiologists shortages, cost containment, quality improvement needs, and technological advancements. It also addresses the opposition to role development and extension, emphasizing the fundamental impetus for these changes should be to provide high-quality and effective patient-centered care. The paper delves into specific areas of role development and extension for radiographers in CT, including intravenous (IV) cannulation and contrast media administration, performing CT colonoscopy examinations, reporting on CT brains, and the significance of research and clinical audit in CT. It underscores the potential benefits of these expanded roles, such as improved patient care, workflow efficiency, and the workload of radiologists, as well as advancements in education, service delivery, and technological innovations. The review underscores the need for further research to ensure evidence-based implementation of role development and extension for radiographers in CT. Embracing these changes and providing the necessary support and training can lead to improved patient care, address skill shortages, and advance the radiography profession in resource-constrained settings like Zimbabwe.
计算机断层扫描(CT)技术已发展成为现代医疗实践中的重要诊断工具,从而促进了 CT 放射技师作用的发展和扩大。虽然一些国家在发展和扩展 CT 放射技师的职责方面取得了进展,但像津巴布韦这样资源有限的国家在实施这些变革方面却进展缓慢。本综述旨在通过回顾有关 CT 放射技师角色发展和延伸的文献,为津巴布韦及类似环境中放射技师的角色转变提供参考。该综述探讨了角色发展和延伸的概念,强调了由于放射医师短缺、成本控制、质量改进需求和技术进步等因素而改变放射技师在 CT 中的角色的必要性。论文还讨论了反对角色发展和延伸的观点,强调这些变化的根本动力应该是提供高质量和有效的以患者为中心的医疗服务。论文深入探讨了 CT 放射技师角色发展和延伸的具体领域,包括静脉(IV)插管和造影剂管理、执行 CT 结肠镜检查、CT 脑部报告以及 CT 研究和临床审计的意义。它强调了这些角色扩展的潜在益处,如改善患者护理、提高工作流程效率、减轻放射医师的工作量,以及在教育、服务提供和技术创新方面的进步。审查强调了进一步研究的必要性,以确保以证据为基础实施 CT 放射技师的角色发展和扩展。接受这些变化并提供必要的支持和培训可以改善患者护理,解决技能短缺问题,并在津巴布韦这样资源有限的环境中推动放射学专业的发展。
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引用次数: 0
Traumatic dental injuries in a tertiary institution in Nigeria: a 4-year retrospective analysis 尼日利亚一所高等院校的牙科外伤:4 年回顾性分析
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.423
M. Adeyemi, M. Ernest, Shakira Sanni-Abdullahi, Ehigie Igben, Ashiru Garba, Mirian Nnebedum
 Background;  Traumatic dental injury (TDI) has grown to be a significant public health issue due to its high prevalence as well as the significant negative effects it has on quality of life. This study aimed to examine the prevalence and causes of TDI in a  Dental outpatient clinic for 4 years. Method: A retrospective study was conducted on 52 TDI patients who were treated at a Tertiary Institution's Dental Outpatient clinic between June 1, 2017, and June 1, 2021.  Data on age, gender, etiology, types of teeth involved, types of dental trauma, the day the incidents occurred, and treatment options were retrieved. Traumatized teeth were classified using Andreasen’s classification. Statistical analysis was carried out using SPSS version 20.0. Result   A total of 208 patients with maxillofacial injuries (163 males and 45 females) aged 1 to 81 years were examined. The prevalence of TDI was 25%. Male and female prevalences were 18.2% and 6.7%, respectively. There were 52 TDI patients  with a mean age of 16.5  ±  12.02. The most common reason for TDI was motorcycle accidents at 30.77%. Avulsion(40.67%) and subluxation(50%) were the most frequently diagnosed injuries in the permanent dentition and primary dentition, respectively. There was no association between trauma source and dentition type (p=0.342), nor was there a difference between trauma source and gender(p=0.863). Conclusion.The study observed that a high percentage of 40.38% had an injury to three or more teeth resulting in attendant functional and esthetic complications. Hence public health issue that warrants urgent government attention.
背景;由于牙外伤(TDI)的高发病率及其对生活质量造成的严重负面影响,它已逐渐成为一个重要的公共卫生问题。本研究旨在调查牙科门诊 4 年来 TDI 的发病率和原因。研究方法本研究对 2017 年 6 月 1 日至 2021 年 6 月 1 日期间在某高等院校牙科门诊接受治疗的 52 名 TDI 患者进行了回顾性研究。 研究检索了年龄、性别、病因、涉及牙齿类型、牙外伤类型、事件发生日期和治疗方案等数据。外伤牙齿采用 Andreasen 分类法进行分类。统计分析使用 SPSS 20.0 版进行。结果 共检查了 208 名颌面部损伤患者(男性 163 名,女性 45 名),年龄在 1 至 81 岁之间。TDI 患病率为 25%。男性和女性的发病率分别为 18.2% 和 6.7%。52 名 TDI 患者的平均年龄为(16.5 ± 12.02)岁。造成 TDI 的最常见原因是摩托车事故,占 30.77%。撕脱伤(40.67%)和半脱位(50%)分别是恒牙和基牙中最常见的损伤。创伤来源与牙列类型之间没有关联(P=0.342),创伤来源与性别之间也没有差异(P=0.863)。结论:研究发现,40.38%的患者有三颗或三颗以上的牙齿受过伤,导致功能和美观方面的并发症。因此,这一公共卫生问题需要引起政府的紧急关注。
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引用次数: 0
Knowledge, attitude and readiness to use contraceptives among postpartum women at a tertiary hospital in southwest Nigeria. 尼日利亚西南部一家三级医院产后妇女对使用避孕药具的了解、态度和意愿。
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.411
O. Ogunbode, Temitope Azeez Olukunke, R. Abdus-salam
Background: Postpartum family planning is vital in the prevention of unintended pregnancy and closely spaced pregnancies in the first year post-delivery. This study was designed to examine the postpartum women’s knowledge, attitude, belief and readiness to contraceptive use. Methods: This descriptive cross-sectional study was conducted in the postnatal clinic of the University College Hospital, Ibadan, Nigeria using an interviewer-assisted structured questionnaire among one hundred and ninety-four consenting recently delivered women. Data was analysed using IBM Statistics for Windows Version 23.0. Tests of association was done using chi-square and statistical significance was set at p-value of < 0.05. Results: Many of the respondents (60.8%) were in the age group 30-39 years and the majority (90.3%) had tertiary level of education. Most of the respondents got their information from health talks at antenatal clinic (42.8%) and health workers (42.3%). The majority (82.5%) of respondents were aware of contraception and 157(80.9%) intended to use contraceptives, however, only 54(34.4%) were willing to adopt a method at the postnatal clinic visit. The most preferred contraceptive methods were implants (23.4%). Respondents with three or more children alive(p=0.001), had statistically significant associations with prior use of contraception while those with the tertiary level of education(p=0.001) and of the Christian religion (p=<0.001) had statistically significant associations with good knowledge of contraception.  Conclusion:  The knowledge and readiness to use contraceptives was high but only about half were willing to adopt a method at the postnatal clinic. Robust prenatal counselling may help to increase the uptake of postpartum contraception.
背景:产后计划生育对于预防产后第一年内的意外怀孕和间隔过短的怀孕至关重要。本研究旨在调查产后妇女对使用避孕药具的知识、态度、信念和意愿。研究方法这项描述性横断面研究是在尼日利亚伊巴丹大学学院医院的产后门诊进行的,在 194 名同意的新近分娩的妇女中使用了由访谈员协助的结构化问卷。数据使用 IBM 统计学视窗版 23.0 进行分析。使用卡方检验关联性,统计显著性以 p 值小于 0.05 为标准。结果许多受访者(60.8%)的年龄在 30-39 岁之间,大多数受访者(90.3%)受过高等教育。大多数受访者(42.8%)从产前诊所的健康讲座和卫生工作者(42.3%)那里获得信息。大多数受访者(82.5%)了解避孕知识,157 名受访者(80.9%)打算使用避孕药具,但只有 54 名受访者(34.4%)愿意在产后就诊时采用避孕方法。最受欢迎的避孕方法是皮下埋植避孕法(23.4%)。有三个或三个以上存活子女的受访者(p=0.001)与之前使用避孕药具有显著的统计学关联,而受过高等教育(p=0.001)和信奉基督教(p=<0.001)的受访者与避孕知识的丰富程度有显著的统计学关联。 结论 使用避孕药具的知识和意愿都很高,但只有约一半的人愿意在产后诊所采用避孕方法。强有力的产前咨询可能有助于提高产后避孕率。
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引用次数: 0
Prevalence and Factors associated with Short Interpregnancy Intervals among women attending antenatal care at first level hospitals in lusaka, zambia. 在赞比亚卢萨卡一级医院接受产前检查的妇女中,孕间隔短的发生率和相关因素。
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.352
Imanga Ikabongo, B. Vwalika, M. Lubeya
INTRODUCTION The Interpregnancy Interval (IPI’s) is defined as the spacing between a live birth and the beginning of the following pregnancy according to the world health organization. Research has shown that short IPI’s are associated with adverse maternal and perinatal outcomes. The IPI therefore offers an opportunity for women to optimize their health status in between pregnancies for better pregnancy outcomes. AIMS AND OBJECTIVES This study was aimed at determining the prevalence of short IPI’s and further determining the demographic, sociocultural and health care related factors associated with short IPI’s among women of reproductive age in Lusaka, Zambia. METHODOLOGY This was a cross sectional study involving 218 women aged between 15 and 49 years attending antenatal clinics at selected hospitals. Eligible participants were recruited using systematic random sampling method and a structured interviewer administered questionnaire was used to collect the data which was later processed using Epi-Data and exported to STATA for analysis. RESULTS The results of this study revealed that the prevalence of short IPI’s was 33.4%. Among the factors associated with short IPI’s, it was noted that women aged 35 years or older were 61% (aOR=0.39;95% CI:0.21-0.98) less likely to have short IPI’s compared to those aged less than 25 years. Furthermore, women from Matero hospital had 4.89 (95% CI; 2.59-11.6) times higher odds of short IPI’s than women from Chawama hospital. In addition, women who reported having discussed the pregnancy with their partners were 59% (aOR=0.41; 95% CI; 0.31-0.96) less likely to have short IPI’s compared to those who did not discuss. For those women who indicated that they did not receive information about recommended IPI’s from health care workers, their odds of short IPI’s were 4.47% (95% CI; 1.57-12.6) times higher than those who received the information. CONCLUSION Based on the results of this study, raising awareness among women on the recommended birth intervals and encouraging partner participation on when to have the next child may help in efforts to avert the problem of short IPI’s and its effect on maternal and perinatal outcomes. KEY WORDS : Short interpregnancy intervals, antenatal care, maternal adverse outcomes, perinatal adverse outcomes
引言 根据世界卫生组织的定义,孕间隔(IPI's)是指活产与下一次怀孕开始之间的间隔时间。研究表明,较短的 IPI 与不良的孕产和围产期结果有关。因此,IPI 为妇女提供了在两次怀孕之间优化自身健康状况以改善妊娠结局的机会。目的和目标 本研究旨在确定赞比亚卢萨卡育龄妇女中 IPI 偏短的发生率,并进一步确定与 IPI 偏短相关的人口、社会文化和医疗保健因素。方法 这是一项横断面研究,共有 218 名年龄在 15 至 49 岁之间的妇女在选定的医院产前门诊就诊。采用系统随机抽样方法招募了符合条件的参与者,并使用结构化访谈问卷收集数据,随后使用 Epi-Data 对数据进行处理,并导出至 STATA 进行分析。结果 研究结果显示,IPI 短的发生率为 33.4%。在与 IPI 短小相关的因素中,年龄在 35 岁或以上的女性与年龄在 25 岁以下的女性相比,IPI 短小的可能性降低了 61%(aOR=0.39;95% CI:0.21-0.98)。此外,来自 Matero 医院的妇女出现 IPI 短的几率是来自 Chawama 医院妇女的 4.89 倍(95% CI;2.59-11.6)。此外,与未与伴侣讨论过怀孕问题的妇女相比,与伴侣讨论过怀孕问题的妇女发生 IPI 短的几率要低 59% (aOR=0.41; 95% CI; 0.31-0.96)。对于那些表示没有从医护人员那里获得有关建议 IPI 的信息的妇女来说,她们的 IPI 短的几率是那些获得相关信息的妇女的 4.47% (95% CI; 1.57-12.6) 倍。结论 根据这项研究的结果,提高妇女对推荐生育间隔的认识并鼓励伴侣参与决定何时生育下一个孩子,可能有助于避免 IPI 短的问题及其对孕产妇和围产期结果的影响。关键字 :孕期间隔过短、产前护理、孕产妇不良结局、围产期不良结局
{"title":"Prevalence and Factors associated with Short Interpregnancy Intervals among women attending antenatal care at first level hospitals in lusaka, zambia.","authors":"Imanga Ikabongo, B. Vwalika, M. Lubeya","doi":"10.55320/mjz.50.3.352","DOIUrl":"https://doi.org/10.55320/mjz.50.3.352","url":null,"abstract":"INTRODUCTION \u0000The Interpregnancy Interval (IPI’s) is defined as the spacing between a live birth and the beginning of the following pregnancy according to the world health organization. Research has shown that short IPI’s are associated with adverse maternal and perinatal outcomes. The IPI therefore offers an opportunity for women to optimize their health status in between pregnancies for better pregnancy outcomes. \u0000AIMS AND OBJECTIVES \u0000This study was aimed at determining the prevalence of short IPI’s and further determining the demographic, sociocultural and health care related factors associated with short IPI’s among women of reproductive age in Lusaka, Zambia. \u0000METHODOLOGY \u0000This was a cross sectional study involving 218 women aged between 15 and 49 years attending antenatal clinics at selected hospitals. Eligible participants were recruited using systematic random sampling method and a structured interviewer administered questionnaire was used to collect the data which was later processed using Epi-Data and exported to STATA for analysis. \u0000RESULTS \u0000The results of this study revealed that the prevalence of short IPI’s was 33.4%. Among the factors associated with short IPI’s, it was noted that women aged 35 years or older were 61% (aOR=0.39;95% CI:0.21-0.98) less likely to have short IPI’s compared to those aged less than 25 years. Furthermore, women from Matero hospital had 4.89 (95% CI; 2.59-11.6) times higher odds of short IPI’s than women from Chawama hospital. In addition, women who reported having discussed the pregnancy with their partners were 59% (aOR=0.41; 95% CI; 0.31-0.96) less likely to have short IPI’s compared to those who did not discuss. For those women who indicated that they did not receive information about recommended IPI’s from health care workers, their odds of short IPI’s were 4.47% (95% CI; 1.57-12.6) times higher than those who received the information. \u0000CONCLUSION \u0000Based on the results of this study, raising awareness among women on the recommended birth intervals and encouraging partner participation on when to have the next child may help in efforts to avert the problem of short IPI’s and its effect on maternal and perinatal outcomes. \u0000KEY WORDS : Short interpregnancy intervals, antenatal care, maternal adverse outcomes, perinatal adverse outcomes","PeriodicalId":74149,"journal":{"name":"Medical journal of Zambia","volume":"59 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140476248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BOWEL OBSTRUCTION FROM COMPLETE TRANSMURAL MIGRATION OF A GOSSYPIBOMA INTO THE ILEUM; A RARE OCCURRENCE 格氏肉瘤完全跨壁移入回肠造成肠梗阻;罕见病例
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.416
H. Agada, Yakubu MALGWA ISHAKU, Joel Iliya
Gossypibomas are infrequent abdominal pathology associated with increased morbidity and mortality. They are foreign bodies of predominantly cotton material that are erroneously left in body cavities following surgery. They represent an extremely rare but avoidable cause of bowel obstruction and should be considered as a differential diagnosis in patients presenting with Bowel obstruction following previous abdominal surgery. We present the case of a young woman with clinical features in keeping with mechanical bowel obstruction from suspected post-operated adhesion. However, intra-operative finding revealed a complete transmural migration of a Gossypiboma into the terminal ileum. She had segmental ileal resection, extraction of the gossypiboma and primary end-to-end ileo-ileal anastomosis. Her recovery period was uneventful. Keywords; Anastomosis, Bowel obstruction, Gossypiboma, laparotomy
棉花瘤是一种不常见的腹部病变,会增加发病率和死亡率。它们是手术后误留在体腔内的异物,主要由棉花材料构成。它们是一种极为罕见但可避免的肠梗阻病因,应作为既往腹部手术后出现肠梗阻的患者的鉴别诊断。我们介绍了一例年轻女性的病例,其临床特征与疑似术后粘连引起的机械性肠梗阻相符。然而,术中发现 Gossypiboma 完全跨壁移入回肠末端。她接受了回肠节段切除术,取出了格氏纤维瘤,并进行了回肠末端至末端吻合术。术后恢复顺利。关键词;吻合术 肠梗阻 格氏纤维瘤 开腹手术
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引用次数: 0
Gastrointestinal malignancies in Zambia: a scoping review 赞比亚的胃肠道恶性肿瘤:范围界定审查
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.400
Pharidah Rajan Ibrahim Omar Sundi, A. Asombang, Nkengeh N. Tazinkeng, Lisa Liang Philpotts, A. Adekunle, Rodrigue Ndabashinze
Background Gastrointestinal (GI) malignancies account for greater than one-third of cancer-related deaths worldwide. In Zambia, there is a lack of data on epidemiology, diagnosis, management, and outcomes. We sought to review existing literature to determine the extent of research and identify gaps in knowledge pertaining to GI malignancies in Zambia. Methods We systematically searched databases including Ovid MEDLINE, CINAHL, Web of Science Core Collection, Cochrane Library via Ovid, Embase, Africa Wide Information via Ebsco, African Index Medicus and African Journals Online, to identify studies on GI malignancies including colorectal (CRC), pancreatic (PC), gastric (GC), esophageal (EC) and liver cancers (LC) in Zambia.  Results Of 323 studies screened, 27 were included in the final analysis. The included studies assessed an individual GI cancer or more than one GI cancer as follows: GC only (n=10, 37%), EC only (n=5, 18%), LC only (n=5, 18%), CRC only (n=2, 7%), PC only (n=1, 4%), PC, CRC, EC, GC, LC combined (n=1, 4%), CRC, EC, GC, LC combined (n=1, 4%), CRC, EC, GC combined (n=1, 4%) and EC, GC combined (n=1, 4%). Gastric cancer was the most studied (n =14 articles), followed by esophageal (n=9 articles), liver cancer (n=7 articles), colorectal (n=5 articles) and pancreatic cancer (n=2 articles).  Conclusion There is paucity of published data. Existing studies have focused mainly on prevalence and risk factors. Longitudinal studies examining incidence, prognosis and survival are needed.    Keywords: Gastrointestinal cancer, Zambia, risk factors, management, clinical outcomes.  
背景 胃肠道(GI)恶性肿瘤占全球癌症相关死亡人数的三分之一以上。在赞比亚,缺乏有关流行病学、诊断、管理和结果的数据。我们试图对现有文献进行回顾,以确定研究范围,并找出赞比亚消化道恶性肿瘤相关知识的不足之处。方法 我们系统地检索了 Ovid MEDLINE、CINAHL、Web of Science Core Collection、Cochrane Library via Ovid、Embase、Africa Wide Information via Ebsco、African Index Medicus 和 African Journals Online 等数据库,以确定有关赞比亚消化道恶性肿瘤(包括结直肠癌 (CRC)、胰腺癌 (PC)、胃癌 (GC)、食管癌 (EC) 和肝癌 (LC) 的研究。 结果 在筛选出的 323 项研究中,27 项被纳入最终分析。纳入的研究对一种或多种消化道癌症进行了评估,具体情况如下:仅 GC(n=10,37%),仅 EC(n=5,18%),仅 LC(n=5,18%),仅 CRC(n=2,7%),仅 PC(n=1,4%),PC、CRC、EC、GC、LC 合并(n=1,4%),CRC、EC、GC、LC 合并(n=1,4%),CRC、EC、GC 合并(n=1,4%)以及 EC、GC 合并(n=1,4%)。研究最多的是胃癌(n=14 篇文章),其次是食管癌(n=9 篇文章)、肝癌(n=7 篇文章)、结直肠癌(n=5 篇文章)和胰腺癌(n=2 篇文章)。 结论 已发表的数据很少。现有研究主要侧重于发病率和风险因素。需要对发病率、预后和存活率进行纵向研究。 关键词胃肠道癌症、赞比亚、风险因素、管理、临床结果。
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引用次数: 0
Phytochemical Screening, median lethal dose and effects of Cassia abbreviata Oliv. crude extracts and fractions on oral glucose tolerance in non-diabetic male Wistar rats 草决明粗提取物和馏分的植物化学筛选、中位致死剂量及对非糖尿病雄性 Wistar 大鼠口服葡萄糖耐量的影响
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.427
E. Musenge, L. Prashar, C. Ezeala, Fastone Mathews Goma
Background: Cassia abbreviata plant extracts are used traditionally to treat various ailments including diabetes mellitus. However, very few animal studies have been conducted to investigate potential hypoglycaemic effects locally. We examined phytochemicals, median lethal dose and effects of Cassia abbreviata extracts and fractions on oral glucose tolerance in non-diabetic male Wistar rats. Methods: Qualitative and Lorke’s methods were used to screen for phytochemicals and acute toxicity testing. Rats weighing 160 - 250 g were divided into 4 groups of 3 rats (phase one) and 4 groups of 1 rat (phase two) each for acute toxicity. Main experiments comprised 8 groups (extracts) and 7 groups (fractions) of 6 rats per group. Doses of 762 mgkg-1, 381 mgkg-1, and 190 mgkg-1 for extracts, 381 mg.kg-1 for the fractions, 10 mg.kg-1 for sitagliptin and 10 mL.kg-1 of vehicle were administered. Thereafter, blood glucose levels were assessed using Accu-Chek glucometer. Results: Leaf methanolic extract and ethyl acetate fraction contained more phytochemicals. Acute toxicity test revealed no mortality in all the groups except for leaf ethanolic and methanolic crude extracts in phase two at dose 5000 mg.kg-1. Root bark ethanolic extract 381 mg.kg-1 showed significant hypoglycaemic effect at 60 min and 180 min while 381 mg.kg-1 n-hexane fraction showed significant hypoglycaemic effect only at 180 min. Sitagliptin 10 mg.kg-1 minimally reduced the blood glucose levels at 60 min. Conclusion: More phytochemicals were observed in leaf methanolic extract and ethyl acetate fraction. Both extracts and fractions were considered practically non-toxic following acute toxicity testing. Root bark ethanolic extract and n-hexane fraction revealed better hypoglycaemic effects. Hypoglycaemic bioactivity observed may be due to various mechanisms.
背景:决明子植物提取物传统上用于治疗包括糖尿病在内的各种疾病。然而,很少有动物实验对其潜在的局部降血糖作用进行研究。我们研究了植物化学物质、中位致死剂量以及决明提取物和馏分对非糖尿病雄性 Wistar 大鼠口服葡萄糖耐量的影响。研究方法采用定性和 Lorke 方法筛选植物化学物质并进行急性毒性测试。将体重为 160 - 250 克的大鼠分为 4 组,每组 3 只(第一阶段)和 4 组,每组 1 只(第二阶段),进行急性毒性试验。主要实验包括 8 组(提取物)和 7 组(馏分),每组 6 只大鼠。提取物的剂量为 762 毫克/千克-1、381 毫克/千克-1 和 190 毫克/千克-1,馏分的剂量为 381 毫克/千克-1,西他列汀的剂量为 10 毫克/千克-1,载体的剂量为 10 毫升/千克-1。之后,使用 Accu-Chek 血糖仪评估血糖水平。结果叶片甲醇提取物和乙酸乙酯馏分含有更多的植物化学物质。急性毒性试验表明,除第二阶段剂量为 5000 毫克/千克的叶乙醇提取物和甲醇粗提取物外,所有组均无死亡。根皮乙醇提取物 381 毫克/千克-1 在 60 分钟和 180 分钟内有明显的降血糖作用,而正己烷馏分 381 毫克/千克-1 仅在 180 分钟内有明显的降血糖作用。西他列汀 10 毫克.千克-1 能在 60 分钟内将血糖水平降至最低。结论在叶片甲醇提取物和乙酸乙酯馏分中观察到了更多的植物化学物质。经过急性毒性测试,这两种提取物和馏分被认为实际上是无毒的。根皮乙醇提取物和正己烷馏分的降血糖效果更好。观察到的降血糖生物活性可能有多种机制。
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引用次数: 0
Lipoprotein (a) as a cause of premature coronary artery disease; a case report of a 34-year-old male patient presenting with ST elevation myocardial infarction. 脂蛋白(a)是过早出现冠状动脉疾病的原因;一名 34 岁男性患者因 ST 段抬高型心肌梗死而引发的病例报告。
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.403
Kateta Edward, Jane Chanda Kabwe, Agness Mtaja, L. Kabwe
Background Premature coronary artery disease (PCAD) is considered when coronary artery disease (CAD) occurs in the younger population, less than 45 years old in males. Modifiable risk factors are present in about 80% of patients with PCAD such as smoking, diabetes, high blood pressure and obesity. High serum lipoprotein (a) level has recently emerged as a risk factor for PCAD. However, it is not routinely investigated in young patients presenting with acute coronary syndromes. Case Presentation A 34-year-old African man presented to our hospital with 2 hours of worsening left sided chest pain. He gave a history of long-standing chest pain in the past that was being managed as peptic ulcer disease. He also complained of a slow heart rate. He had no traditional cardiovascular risk factors. The only significant history was a recent recovery from COVID-19 infection two months prior. His physical examination was only significant for a bradycardia, ECG revealed a hyper acute inferior STEMI without right ventricular involvement. Echo showed a normal left ventricle with reduced ejection fraction (EF: 50%), wall motion abnormalities consistent of an inferior MI. He immediately received streptokinase with good clinical and ECG response. His coronary angiogram showed a severe lesion and plaque rupture in the mid-distal segment of a dominant right coronary artery. Percutaneous coronary intervention (PCI) was successfully done, and one drug eluting stent was implanted. He was placed on guideline directed medical therapy for secondary prevention. The only significant possible aetiology found was an elevated Lipoprotein (a) (137mg/dl). Subsequent serum Lipoprotein (a) remained persistently elevated despite therapy with high dose niacin. He was recommended for a PCSK9 receptor blocker, but this medication is not available in the country and the patient could not meet the costs. He remains stable to current medications with no recurrence of chest pain, two years after the index event, the Lipoprotein (a) levels are still high. Conclusions: Lipoprotein (a) appears to be an important overlooked cardiovascular risk factor for premature coronary artery disease especially in the absence of traditional risk factors. It should always be considered in the screening of premature coronary cardiovascular disease. The acute presentation in this patient was probably triggered by SARS COV-2 infection.
背景早发性冠状动脉疾病(PCAD)是指冠状动脉疾病(CAD)发生在年轻人群中,男性小于 45 岁。约 80% 的 PCAD 患者存在可改变的危险因素,如吸烟、糖尿病、高血压和肥胖。高血清脂蛋白(a)水平最近已成为 PCAD 的一个风险因素。然而,在急性冠状动脉综合征的年轻患者中,并没有对其进行常规检查。病例介绍 一名 34 岁的非洲男子因左侧胸痛加重 2 小时来我院就诊。他自述过去曾有过长期胸痛病史,当时被当作消化性溃疡病治疗。他还抱怨心率缓慢。他没有传统的心血管风险因素。唯一重要的病史是两个月前刚从 COVID-19 感染中恢复。他的体格检查仅发现心动过缓,心电图显示为高急性下STEMI,无右心室受累。回波显示左心室正常,但射血分数降低(EF:50%),室壁运动异常,与下壁心肌梗死一致。他立即接受了链激酶治疗,临床和心电图反应良好。冠状动脉造影显示,他的右冠状动脉中段出现严重病变和斑块破裂。经皮冠状动脉介入治疗(PCI)获得成功,植入了一个药物洗脱支架。他接受了指南指导的二级预防药物治疗。唯一可能的重要病因是脂蛋白(a)升高(137 毫克/分升)。尽管使用了大剂量烟酸治疗,但随后的血清脂蛋白(a)仍持续升高。医生建议他服用 PCSK9 受体阻断剂,但这种药物在国内无法买到,患者也无法承担费用。事件发生两年后,脂蛋白(a)水平仍然很高。结论:脂蛋白(a)似乎是过早发生冠心病的一个被忽视的重要心血管危险因素,尤其是在没有传统危险因素的情况下。在筛查早发冠心病时,应始终考虑到这一点。该患者的急性发病可能是由 SARS COV-2 感染引发的。
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引用次数: 0
Role of Radiographers in the Provision of Diagnostic Medical Ultrasound Services in Zimbabwe: Past, Present and Way Forward 放射技师在津巴布韦医疗超声诊断服务中的作用:过去、现在和未来
Pub Date : 2024-01-31 DOI: 10.55320/mjz.50.3.424
B. Chinene, Lavin Mutandiro, E. Mushosho, Lyman Khumbula, Admire Zanga, Josephat Banhwa, O. Bwanga
Ultrasound imaging is an important tool in healthcare, used for screening, diagnosis, monitoring, and treating diseases. It works by using sound waves to generate images based on echoes reflected back from the object being examined. Advancements in ultrasound technology have made it more accessible to other healthcare professionals, resulting in its expanded application across all fields of medicine. In Zimbabwe, radiographers play a crucial role in providing ultrasound services, helping to address the shortage of radiologists, and improve patient access to quality imaging. However, there is a lack of available literature on ultrasound imaging human resources in Zimbabwe. This article reviews the historical development of ultrasound training for radiographers in Zimbabwe, highlighting the challenges and opportunities associated with their expanded role in ultrasound. It also emphasizes the benefits of involving radiographers in ultrasound services, such as improved patient care, cost savings, utilization of their knowledge and skills, and enhanced job satisfaction. The paper provides recommendations for the future, including the need for clear clinical leadership, specialized ultrasound programs, and continuous professional development (CPD) activities to ensure high-quality ultrasound services in the country. The insights presented aim to inform policy decisions and promote equitable access to essential ultrasound imaging in the Zimbabwean healthcare system.
超声成像是医疗保健领域的重要工具,用于筛查、诊断、监测和治疗疾病。它利用声波根据被检查物体反射回来的回波生成图像。超声波技术的进步使其他医疗保健专业人员更容易获得超声波技术,从而扩大了其在所有医学领域的应用。在津巴布韦,放射技师在提供超声波服务方面发挥着至关重要的作用,有助于解决放射科医生短缺的问题,并改善患者获得高质量成像的机会。然而,目前缺乏有关津巴布韦超声成像人力资源的文献资料。本文回顾了津巴布韦放射技师超声培训的历史发展,强调了他们在超声领域扩大角色所带来的挑战和机遇。文章还强调了放射技师参与超声服务的好处,如改善患者护理、节约成本、利用他们的知识和技能以及提高工作满意度。论文对未来提出了建议,包括需要明确的临床领导、专门的超声项目和持续的职业发展(CPD)活动,以确保该国提供高质量的超声服务。本文提出的见解旨在为津巴布韦医疗保健系统的决策提供参考,并促进公平获得基本的超声成像服务。
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引用次数: 1
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Medical journal of Zambia
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