Mean arterial pressure, pulse pressure in diabetic and non diabetic male African population: a comparative study

Mean arterial pressure and pulse pressure are important parameters that predicts cardiovascular risk both in diabetics and non diabetic population in both gender. Data on this subject area in Nigeria, Africa and worldwide are few. It was estimated that in the United States 30% of inpatient cost (around 22,254 million US dollars) was due to cardiovascular vascular disease (CVD) hospitalization among people with type 2 diabetes in 2012.1,2 An even greater diabetes-attributable hospitalization cost of 46.5% was found in a major hospital in Cambridge shire, England.3 A paradoxical finding is that the wellknown relationship between CVD and systolic blood pressure in the general population was insignificant in a meta-analysis using data from people with diabetes.4 Greater use of antihypertensive medicine and a higher prevalence of heart failure than people without diabetes have been proposed as possible reasons for this paradox.5,6 Mean arterial pressure (MAP) reflects both peripheral resistance and cardiac output. Recently, in the ADVANCE study,7 a trial among type 2 diabetes patients, MAP correlated with major CVD events: with a 13% increase in risk per 13 mmHg increase in MAP. If MAP is a marker for