精神健康合并症对儿童注意缺陷多动障碍社区治疗和预后的影响

Nour Al Ghriwati, Joshua M. Langberg, W. Gardner, J. Peugh, K. Kelleher, Rebecca A. Baum, William B. Brinkman, P. Lichtenstein, J. Epstein
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引用次数: 16

摘要

目的:患有注意缺陷多动障碍(ADHD)的儿童经常表现出精神合并症,这可能会影响疾病的表现、诊断和治疗结果。已有处理这些复杂病例的指南,但对社区儿科环境中如何处理合并症知之甚少。本研究的目的是评估精神健康合并症如何影响社区医生的ADHD护理实践和患者的症状轨迹。方法:回顾了319名在初级保健诊所就诊的adhd相关儿童的病历。提取医生评估和治疗行为,家长在诊断时以及3、6和12个月时对ADHD症状进行评分。基线评分用于对儿童进行分组,分为无共病精神健康状况、内化或外化共病状况。多水平分析比较了社区医生护理行为和不同群体的ADHD症状轨迹。结果:大约50%的样本符合共病精神健康状况的筛查标准。对于诊断为ADHD并接受药物治疗的儿童,社区医生的护理在各组之间基本上没有差异,但与没有合并症的儿童相比,有内化合并症的儿童在注意力不集中和多动/冲动症状方面的改善明显较小。结论:患有ADHD和精神健康合并症的儿童,特别是内化障碍,对ADHD药物的反应较弱,可能需要在开始药物治疗和/或替代治疗方法之前进行额外的测试。讨论了进行综合评估和提供多模式治疗的潜在障碍。
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Impact of Mental Health Comorbidities on the Community-Based Pediatric Treatment and Outcomes of Children with Attention Deficit Hyperactivity Disorder
Objective: Children with attention deficit hyperactivity disorder (ADHD) often exhibit psychiatric comorbidities, which may impact illness presentation, diagnosis, and treatment outcomes. Guidelines exist for dealing with these complex cases but little is known about how comorbidities are being handled in community pediatric settings. The purpose of this study was to evaluate how mental health comorbidities affect community physicians' ADHD care practices and patients' symptom trajectories. Method: Medical charts of 319 children presenting at primary care clinics for ADHD-related concerns were reviewed. Physician assessment and treatment behaviors were extracted and parents rated ADHD symptoms at the time of diagnosis and at 3, 6, and 12 months. Baseline ratings were used to group children, as no comorbid mental health condition, internalizing, or externalizing comorbid condition. Multilevel analyses compared community physician care behaviors and ADHD symptom trajectories across groups. Results: Approximately, 50 percent of the sample met screening criteria for a comorbid mental health condition. For children diagnosed with ADHD and treated with medication, community physician care largely did not differ across groups, but children with internalizing comorbidities made significantly smaller improvements in inattentive and hyperactive/impulsive symptoms compared with children with no comorbidities. Conclusion: Children with ADHD and mental health comorbidities, particularly internalizing disorders, exhibit less robust response to ADHD medication and may require additional testing before starting medication and/or alternative treatment approaches. Potential barriers to conducting comprehensive assessments and to providing multi-modal treatment are discussed.
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