Antimicrobial Effect of Rheum ribes and Tio2 Nps on Bacterial Biofilm in Escherichia Coli

Rheum ribs reported to have used in traditional medicine system, and also used as antimicrobial agent against different species of bacteria. Tio2 NPs one of the most widely material that investigated for killing or inhibition of bacteria. In order that, this research was came to study the effects of antibiofilm R. ribs extract and Tio2 on uropathogenic E. coli. Furthermore, study the effect of R. ribs and Tio2 combination by using tissue culture plate method. The results showed that R. ribs extract and Tio2 gave inhibition effect against bacterial biofilm in high percentage (60-80%) and (65-76%) respectively, the first effect on (E7-E16) and the second (E9E16), but the highly effect observed when mix each one of them with others one in percentage (60-78%) against 11 bacterial isolates from (E6-E16). From these results we can concluded that the R. ribs extract and Tio2 may act as an antibacterial agents in thefuture.