药用植物提取物对人致病菌甲型副伤寒沙门菌和乙型副伤寒沙门菌的天然抗菌评价

IF 7.6 2区 工程技术 Q1 CHEMISTRY, APPLIED Annual review of chemical and biomolecular engineering Pub Date : 2021-07-06 DOI:10.11648/j.cbe.20210602.11
Janki Ruparelia, Aniruddh Rabari, Nishra Joshi, Asha Dhediya, Jigisha Halpati, Ankita A. Patel, C. Jha
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引用次数: 3

摘要

尽管有大量的合成产品和高通量的生物测试策略,天然化合物仍然是抗菌药物开发的主要来源。这些化合物是独一无二的珍贵,因为它们经历了自然的分类。本研究主要研究了印度药用植物Ocimum sanctum、Phyllanthus emblica和Bryophyllum pinnatum抵御人类致病菌副伤寒沙门氏菌A和b的民族植物学功效。对这些植物进行了生物碱、类黄酮、单宁、类固醇、糖苷、碳水化合物和氨基酸等成分的植物化学筛选。琼脂孔扩散法测定了这些植物的乙醇提取物对人体病原菌有良好的活性,并记录了其MIC值。这些植物对甲型副伤寒沙门菌和乙型副伤寒沙门菌的平均抑制区分别在4 ~ 29 mm和4 ~ 27 mm之间。这些结果实现了药用植物的抗菌潜力,从而为其在传统医学中的使用提供了支持。
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Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B
Regardless of the convenience of plentiful miscellaneous collection of synthetic products and high-throughput tactics for their biological testing, natural compounds twig at a major source for antimicrobial drug development. These compounds are exclusively treasured as they have endured natural assortment over time. In this study we concentrated on Ethnobotanical efficacy of Indian medicinal plants like Ocimum sanctum, Phyllanthus emblica and Bryophyllum pinnatum for defence against bacterial human pathogen salmonella paratyphi A and salmonella paratyphi B. Phytochemical screening of these plants was executed for constituents like alkaloids, flavonoids, tannins, steroids, glycosides, carbohydrates and aminoacids. The ethanol extract of these plants exhibited good activity against the human pathogens by agar well diffusion assay method and the MIC was recorded. Average mean zone of inhibition found by these plants ranged between 4 mm to 29 mm and 4 mm to 27 mm respectively for salmonella paratyphi A and salmonella paratyphi B. These results accomplish the antimicrobial potential of the medicinal plants and hence convey upkeep for the use of them in traditional medicine.
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来源期刊
Annual review of chemical and biomolecular engineering
Annual review of chemical and biomolecular engineering CHEMISTRY, APPLIED-ENGINEERING, CHEMICAL
CiteScore
16.00
自引率
0.00%
发文量
25
期刊介绍: The Annual Review of Chemical and Biomolecular Engineering aims to provide a perspective on the broad field of chemical (and related) engineering. The journal draws from disciplines as diverse as biology, physics, and engineering, with development of chemical products and processes as the unifying theme.
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