Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath
{"title":"青少年男性复发性丘疹性坏死结核:诊断困境","authors":"Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath","doi":"10.4103/jdds.jdds_5_22","DOIUrl":null,"url":null,"abstract":"Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"142 1","pages":"51 - 53"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recurrent papulonecrotic tuberculid in an adolescent male: A diagnostic dilemma\",\"authors\":\"Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath\",\"doi\":\"10.4103/jdds.jdds_5_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.\",\"PeriodicalId\":15535,\"journal\":{\"name\":\"Journal of Dermatology and Dermatologic Surgery\",\"volume\":\"142 1\",\"pages\":\"51 - 53\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Dermatology and Dermatologic Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jdds.jdds_5_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Dermatology and Dermatologic Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jdds.jdds_5_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Recurrent papulonecrotic tuberculid in an adolescent male: A diagnostic dilemma
Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.