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Squamomelanocytic tumor of the plantar aspect of the foot: A collision tumor 足底鳞状黑色素细胞瘤:一种碰撞瘤
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_43_22
J. Pandiaraja, Natarajan Ramya
Collision tumors are two cancers that coexist in the same anatomical site. The etiopathogenesis of collision tumors remains controversial. Even though collision is uncommon, the association between squamous cell carcinoma and malignant melanoma is very rare compared to basal cell carcinoma and malignant melanoma. Here, we report a case of squamous cell carcinoma with malignant melanoma which was confirmed by histopathological examination and immunohistochemistry. The patient underwent wide local excision and flap cover. This case is reported due to the rarity.
碰撞肿瘤是在同一解剖部位共存的两种癌症。碰撞瘤的发病机制仍有争议。尽管碰撞并不常见,但与基底细胞癌和恶性黑色素瘤相比,鳞状细胞癌和恶性黑色素瘤之间的联系非常罕见。在此,我们报告一例经组织病理检查和免疫组织化学证实的鳞状细胞癌合并恶性黑色素瘤。患者接受了广泛的局部切除和皮瓣覆盖。本病例因罕见而被报道。
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引用次数: 0
Single arm unicentric study to evaluate the efficacy of autologous noncultured nontrypsinized epidermal cell grafting (Jodhpur technique) in stable acral vitiligo 单臂单中心研究评价自体非培养非胰蛋白酶化表皮细胞移植(Jodhpur技术)治疗稳定型肢端白癜风的疗效
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_15_21
D. Sharma, P. Choudhary, Rahul Singrodia, M. Verma, P. Rao, D. Kachhawa
Background: Autologous noncultured, nontrypsinized melanocyte–keratinocyte grafting (Jodhpur technique [JT]) is an unconventional innovative surgical modality for the treatment of stable vitiligo. Acral vitiligo is considered an area that is difficult to treat with variable results in different studies. Purpose: The aim of this study was to assess the efficacy and safety of JT in stable acral vitiligo. Methods: This was an open, nonrandomized, and single-arm study. Ninety patches of stable acral vitiligo were included in this study. JT was performed over these patches. The total duration of the study was 48 weeks. The degree of repigmentation was graded into poor (<50% repigmentation), fair (50%–74% repigmentation), good (75%–89% repigmentation), and excellent (90%–100% repigmentation). Results: Out of 90 patches, 81 responded to the surgery. The extent of repigmentation was good to excellent in 61% of patients at week 24 and 70% of patients at week 48. No life-threatening adverse effects were seen. Diffuse pigmentation was seen in 86% of patches. Color match was excellent in most of the patients (91%) with improvement in the Dermatology Life Quality Index (P = 0.0001). Conclusion: JT is a simple, cost-effective, and economical option in the management of stable acral vitiligo with minimal adverse effects.
背景:自体非培养、非胰蛋白酶化黑素细胞-角化细胞移植(Jodhpur技术[JT])是治疗稳定型白癜风的一种非传统的创新手术方式。肢端白癜风被认为是一个难以治疗的领域,不同的研究结果不同。目的:评价JT治疗稳定性肢端白癜风的疗效和安全性。方法:这是一项开放、非随机、单组研究。本研究纳入了90例稳定性肢端白癜风。对这些补片进行了JT检查。研究的总持续时间为48周。再着色程度分为差(<50%再着色)、一般(50% ~ 74%再着色)、好(75% ~ 89%再着色)、优(90% ~ 100%再着色)。结果:90个补片中,81个对手术有反应。61%的患者在第24周和70%的患者在第48周的再色素沉着程度为良好至极好。没有发现危及生命的副作用。86%的斑块可见弥漫性色素沉着。大多数患者(91%)的颜色匹配良好,皮肤病生活质量指数(P = 0.0001)得到改善。结论:JT治疗稳定型肢端白癜风是一种简单、经济、经济的治疗方法,副作用小。
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引用次数: 0
Purse-String closure on the chest, a cosmetically appealing alternative 在胸前的钱包线闭合,一个美容吸引人的选择
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_30_22
K. Pagani, Kaitlin Blankenship, D. Goldberg, Riley McLean-Mandell
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引用次数: 0
Cosmetic dermatology training: Perceptions and experiences of dermatologists and residents in Saudi Arabia 美容皮肤科培训:沙特阿拉伯皮肤科医生和居民的看法和经验
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_86_22
A. Alturki, K. Alekrish, N. Algharbi, Tala Qadoumi, Moath Albusair, Shahad Alghamdi, Asem M. Shadid, Fajer Alzamil, Salma Albarqawi
Background: According to the American Society for Dermatologic Surgery, nearly 12 million dermatological procedures were performed in 2017, of which more than half were cosmetic surgeries. The Saudi population has a positive attitude toward and acceptance of cosmetic surgeries, with a dramatic increase in demand from female patients. Dermatologists are expected to be familiar with several cosmetic procedures, therefore, the quality of residency cosmetic training must be of the highest standards. Purpose: The objective of this study was to assess the experience of dermatologists and dermatology residents regarding cosmetic dermatology training in Saudi Arabia. Methods: A quantitative, cross-sectional, online, questionnaire-based study was conducted from March 2020 to July 2020 among 101 dermatologists and dermatology residents (postgraduate years 2, 3, and 4) in Saudi Arabia. Results: Laser surgery was the most performed procedure (65%), followed by botulinum toxin injection (50%). Experience was lacking and additional training was needed for soft-tissue filling (77%) and chemical peels (60%). A large majority (90%) reported not receiving adequate cosmetic procedures training during their residency. Conclusion: The growing demand for cosmetic operations has increased the need for cosmetic dermatological training. Although most trainees were exposed to esthetic dermatology at some point, this exposure appears inadequate. Improving the curriculum in the dermatology residency program for training in cosmetic procedures may be a priority.
背景:根据美国皮肤外科学会的数据,2017年进行了近1200万例皮肤手术,其中一半以上是整容手术。沙特人对整容手术的态度和接受度都很积极,女性患者的需求急剧增加。皮肤科医生需要熟悉几种美容程序,因此,住院医师美容培训的质量必须达到最高标准。目的:本研究的目的是评估沙特阿拉伯皮肤科医生和皮肤科住院医师关于美容皮肤科培训的经验。方法:从2020年3月到2020年7月,对沙特阿拉伯的101名皮肤科医生和皮肤科住院医师(研究生二、三、四年级)进行了一项定量、横断面、在线、基于问卷的研究。结果:激光手术最多(65%),其次是肉毒毒素注射(50%)。缺乏经验,需要对软组织填充(77%)和化学换肤(60%)进行额外的培训。绝大多数(90%)报告称在住院期间没有接受足够的美容手术培训。结论:美容手术需求的增长,增加了美容皮肤科培训的需求。虽然大多数受训者在某些时候都接触过美容皮肤科,但这种接触似乎是不够的。改善皮肤科住院医师的美容程序培训课程可能是当务之急。
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引用次数: 0
Early neonatal dermatoses: An epidemiological study from a tertiary care center in Western Rajasthan 早期新生儿皮肤病:来自拉贾斯坦邦西部三级保健中心的流行病学研究
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_89_21
P. Choudhary, R. Mehta, Kamaldeep Singh, Vikas Mahla, B. Ghiya, Divyansha Sharma, Ashok Dhanwal
Background: The spectrum of cutaneous manifestations during the neonatal period varies from transient self-limiting conditions to serious life-threatening ones. Transient and pathological neonatal dermatoses should be differentiated from physiological changes to avoid unnecessary treatment and to relieve parent's stress. Purpose: The aim of this study was to determine the incidence and patterns of various dermatoses in early neonates and correlate these changes with maternal or neonatal factors; in the west region of Rajasthan, India. Methods: This hospital-based prospective study at a tertiary-level referral teaching medical center entailed recording detailed dermatological examination of 5000 early neonates having any physiological and/or pathological cutaneous changes. Results: A total of 5000 newborns were observed, there were 3248 (64.96%) male and 1752 (35.04%) female. Out of the total, 67.36% were full-term birth, whereas 30.44% were preterm and 2.2% were postterm newborns. Physiological skin changes (92.42%) were more commonly observed as compared to pathological changes (45.1%). The physiological skin changes observed in the order of frequency were sebaceous hyperplasia (65.32%), milia (51.12%), and physiological scaling (41.02%). Cutis marmorata (2.06%) and harlequin skin changes (1.06%) were seen more in preterms, weighing <2.5 kg. Miliaria was observed in 39% of neonates, due to the hot and humid environment at our place. Bullous impetigo was the most common infection observed in 199 neonates. The most common iatrogenic complication was caput succedaneum; noted in 160 neonates. Conclusion: Neonatal dermatoses are mostly transient and physiological, but these innocent dermatoses need to be differentiated from serious and aggressive pathological dermatoses to avoid unnecessary therapy.
背景:新生儿时期的皮肤表现从短暂的自限性到严重的危及生命的症状不等。应将暂时性和病理性新生儿皮肤病与生理性变化区分开来,避免不必要的治疗,减轻家长的压力。目的:本研究的目的是确定早期新生儿各种皮肤病的发病率和模式,并将这些变化与母体或新生儿因素联系起来;位于印度拉贾斯坦邦西部地区。方法:本前瞻性研究在一家三级转诊教学医疗中心进行,记录了5000名有任何生理和/或病理皮肤变化的早期新生儿的详细皮肤病学检查。结果:共观察新生儿5000例,其中男性3248例(64.96%),女性1752例(35.04%)。其中足月新生儿占67.36%,早产儿占30.44%,早产儿占2.2%。生理性皮肤改变(92.42%)较病理性皮肤改变(45.1%)更为常见。生理性皮肤变化发生率依次为皮脂腺增生(65.32%)、粟疹(51.12%)、生理性结垢(41.02%)。体重<2.5 kg的早产儿多见斑疹(2.06%)和丑角样皮肤变化(1.06%)。由于我们所在的湿热环境,39%的新生儿出现了粟疹。大疱性脓疱疮是199例新生儿中最常见的感染。最常见的医源性并发症是头部继位;在160个新生儿中发现。结论:新生儿皮肤病多为一过性生理性皮肤病,但应与严重侵袭性病理性皮肤病鉴别,避免不必要的治疗。
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引用次数: 0
Depression among adolescents with acne vulgaris: A cross-sectional assessment 患有寻常痤疮的青少年抑郁:一项横断面评估
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_77_22
I. Singh, A. Masih
Background: The prevalence of depression among adolescents and young adults with acne vulgaris has varied widely in different studies. Purpose: The purpose of this study is to assess the prevalence of depression among adolescents with acne vulgaris as compared to age and gender-matched healthy adolescents. The effects of the severity of acne (and postacne scars), duration of acne, and treatment on the severity of depression among adolescents with acne have also been assessed in this study. Methods: The patient health questionnaire-9 was completed by each one of 1502 adolescents with acne vulgaris and 1500 age and gender-matched controls in this cross-sectional study. The association of prevalence and severity of depression with gender, duration of acne, grade of acne, treatments received, and presence and severity of postacne scars was explored by Chi-square test for categorical variables and t-test for quantitative variables. Results: One hundred and thirty (8.65%) adolescents with acne vulgaris were diagnosed with depression, while only 5 (0.33%) healthy adolescents were diagnosed with depression (P = 0.005). Among adolescents with acne vulgaris, 2 (0.13%) had severe depression, 4 (0.27%) had moderately severe depression, 11 (0.73%) had moderate depression, and 113 (7.52%) had mild depression. There was no association of severity of depression with gender, grade of acne (and postacne scars), duration of acne, and treatment received. Conclusion: Acne and postacne scars are associated with a significant prevalence of depression among adolescents with acne independent of treatment received. Clinicians should consider incorporating depression screening and referral system in their workflow with adolescents who access them for acne treatment to achieve better clinical outcomes.
背景:在不同的研究中,患有寻常痤疮的青少年和青壮年抑郁症的患病率差异很大。目的:本研究的目的是评估患有寻常痤疮的青少年与年龄和性别匹配的健康青少年相比抑郁的患病率。该研究还评估了痤疮严重程度(和痤疮后疤痕)、痤疮持续时间和治疗对痤疮青少年抑郁严重程度的影响。方法:采用横断面研究方法,对1502例寻常性痤疮青少年和1500例年龄、性别匹配的对照组分别填写患者健康问卷-9。分类变量采用卡方检验,定量变量采用t检验,探讨抑郁症的患病率和严重程度与性别、痤疮持续时间、痤疮等级、接受过的治疗、痤疮后疤痕存在和严重程度的关系。结果:普通痤疮青少年中有130人(8.65%)被诊断为抑郁症,而健康青少年中只有5人(0.33%)被诊断为抑郁症(P = 0.005)。青少年寻常痤疮患者中,重度抑郁2例(0.13%),中度抑郁4例(0.27%),中度抑郁11例(0.73%),轻度抑郁113例(7.52%)。抑郁症的严重程度与性别、痤疮等级(和痤疮后疤痕)、痤疮持续时间和接受的治疗没有关联。结论:痤疮和痤疮后疤痕与痤疮青少年抑郁症的显著患病率相关,与接受的治疗无关。临床医生应该考虑将抑郁症筛查和转诊系统纳入他们的工作流程中,以获得更好的临床效果。
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引用次数: 0
Hypopigmented pityriasis lichenoides: A new clinicopathological type 一种新的临床病理类型:地衣样癣
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_48_22
A. Mahran, Aya Younis, A. Ahmed, Marwa Mekkawy
Pityriasis lichenoides (PL) presents a spectrum of uncommon inflammatory skin diseases that includes acute and chronic variants. The hypopigmented PL is a rare variant that was reported in dark-skinned individuals. It was proved histologically to be a variant of PL chronica (PLC). To our best knowledge, we report the first case of a hypopigmented variant of PL that shows histopathological features of PLC and PL et varioliformis acuta.
苔藓样糠疹(PL)是一种罕见的炎症性皮肤病,包括急性和慢性变异。低色素的PL是一种罕见的变异,在深色皮肤的个体中有报道。组织学证实为慢性PL (PLC)的一种变体。据我们所知,我们报告了第一例PL的低色素变体,显示了PLC和PL的组织病理学特征。
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引用次数: 0
An evaluation of the management of hirsutism in public versus private outpatient departments in Saudi Arabia 在沙特阿拉伯的公共与私人门诊部门多毛症的管理评估
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_47_22
Malak Aldosari, A. Saleh, Abdubadie Kutubi, Asma Al-Ruhaimi, Y. Bashawri, Arwa Althubyani, Raneem Saleh, H. Khalil
Background: Hirsutism is the excessive body or facial terminal (coarse) hair growth in females in a male-like pattern, carries a worldwide prevalence of 5%–20%, and requires careful evaluation and long-term management. Purpose: The study aims to critically appraise public and private institutions' practices in managing hirsutism, compared against international standards. The purpose of this study was to assess how frequently patients receive counseling to address the causes of hirsutism and to determine if disease severity, screening, and outpatient management vary between public and private clinics in Saudi Arabia. Methods: Patients were recruited from gynecology, endocrine, dermatology, and women's skin care clinics in public (n = 119) and private outpatient clinics (n = 238). Sociodemographics, body mass index (BMI), menstrual cycle rhythm, hirsutism site and scores, associated acne and/or alopecia, family history, and treatment modality received were queried. This study had two groups: Group 1 (n = 119) patients who were seen at public outpatient clinics and Group 2 (n = 238) patients who were seen at private outpatient clinics. Results: The median age was 27 years (range 18–45) and median BMI was 25 kg/m2 (range 16–44). The total mean hirsutism score was 9.3 ± 3.8. The severity of hirsutism was categorized into three groups: mild cases were recorded in 224 women (62.7%), moderate cases were recorded in 94 women (26.3%), and severe cases were recorded in 39 women (10.9%). There was no significant correlation between total mean hirsutism scores, age and BMI, P = 0.5 and P = 0.2, respectively. Approximately one-third of women were seen and investigated by physicians either at public or private clinics and about 70% of women were seen and treated by nonphysician skin care specialist without prior medical investigations in either public or private outpatient departments (OPDs). Conclusion: Assessment and management of hirsutism are similar in the public and private setting. Most patients presented to private rather than public OPDs and were not appropriately investigated for hirsutism. Weight reduction can be beneficial for the management of hirsutism for those with raised BMI and advice should be given accordingly in the OPD setting.
背景:多毛症是指女性身体或面部末端(粗)毛生长过多,与男性相似,在世界范围内的患病率为5%-20%,需要仔细评估和长期管理。目的:该研究旨在批判性地评估公共和私人机构在管理多毛症方面的做法,并与国际标准进行比较。本研究的目的是评估患者接受咨询的频率,以解决多毛症的原因,并确定沙特阿拉伯公立和私立诊所的疾病严重程度、筛查和门诊管理是否存在差异。方法:从公立妇科、内分泌科、皮肤科和女性皮肤护理诊所(n = 119)和私立门诊(n = 238)招募患者。询问社会人口统计、体重指数(BMI)、月经周期节律、多毛部位和评分、相关痤疮和/或脱发、家族史和接受的治疗方式。本研究分为两组:第一组(n = 119)患者在公立门诊就诊,第二组(n = 238)患者在私立门诊就诊。结果:中位年龄为27岁(范围18-45),中位BMI为25 kg/m2(范围16-44)。多毛症的总平均评分为9.3±3.8分。多毛症严重程度分为轻度224例(62.7%),中度94例(26.3%),重度39例(10.9%)。多毛症总平均评分与年龄、BMI无显著相关,P = 0.5、P = 0.2。大约三分之一的女性在公立或私立诊所接受医生的治疗和调查,大约70%的女性在公立或私立门诊(OPDs)接受非医生皮肤护理专家的治疗和治疗,之前没有进行医学调查。结论:多毛症的评估和处理在公共场所和私人场所是相似的。大多数患者就诊于私人门诊而不是公立门诊,没有适当地调查多毛症。体重减轻对那些体重指数升高的多毛症患者是有益的,因此在门诊设置中应该给出相应的建议。
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引用次数: 0
Adult-Onset greither's disease: A rare report of two cases 成人起病的格雷瑟氏病:罕见的两例报告
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_76_22
H. Khan, Ayesha Sharmeen, S. Amin, Bushra Siddiqui
Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood having clinical and histological features of Greither's disease (GD). Only a single report of adult-onset GD has been reported in the literature. All patients presenting with palmoplantar keratoderma should be thoroughly evaluated, as it may be a late-onset inherited disorder, it adds to the spectrum of conditions to presenting with PPKs of late-onset.
遗传性掌跖角化皮病(PPKs)在婴儿期晚期或儿童早期发病,并有积极的家族史。散发性病例和成年发病病例很少报告。我们描述了两例女性PPK变性和前变性,在成年期发病,具有格雷特病(GD)的临床和组织学特征。文献中仅报道过一例成人发病的GD。所有表现为掌跖角化病的患者都应该进行彻底的评估,因为它可能是一种迟发性遗传性疾病,它增加了迟发性ppk的症状范围。
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引用次数: 0
Perforating granuloma annulare mimicking keratoacanthoma: A case report 模拟角棘肿的环形穿孔肉芽肿1例
Pub Date : 2023-01-01 DOI: 10.4103/jdds.jdds_16_22
Dilek Menteşoğlu, H. Khurami, A. Karaduman, Ö. Gököz
Perforating granuloma annulare (PGA) is a infrequent type of granuloma annulare. PGA has a chronic course. The etiology and perforation mechanism are still obscure. We submit a case of a 32-year-old male patient who presented with a 2-month history of asymptomatic lesion on the dorsum of his hand. He did not report the use of any medication, infection, vaccine, trauma, autoimmune disorders, heart disease, and malignancy. Complete blood count, thyroid function tests, lipid profile parameters, and fasting blood glucose were within normal ranges. Moreover, the human immunodeficiency virüs was negative. Histopathologic examination revealed that accumulation of mucin was at the center of the histiocytic reaction, which was grouped in places. Therefore, we diagnosed PGA with clinical and histopathological data. The presented case emphasizes that PGA should be considered in the differential diagnosis of keratotic/ umbilical papules on the dorsum of the hand.
穿孔性环形肉芽肿是一种少见的环形肉芽肿。PGA有慢性病程。病因和穿孔机制仍不清楚。我们报告一个32岁的男性患者,他的手背有2个月的无症状病变史。他没有报告使用任何药物、感染、疫苗、创伤、自身免疫性疾病、心脏病和恶性肿瘤。全血细胞计数、甲状腺功能检查、血脂参数和空腹血糖均在正常范围内。此外,人类免疫缺陷病毒 s为阴性。组织病理学检查显示,黏液积聚在组织细胞反应的中心,并呈成组分布。因此,我们根据临床和组织病理学资料诊断PGA。本病例强调PGA在手背角化/脐丘疹的鉴别诊断中应予以考虑。
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引用次数: 0
期刊
Journal of Dermatology and Dermatologic Surgery
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