Collision tumors are two cancers that coexist in the same anatomical site. The etiopathogenesis of collision tumors remains controversial. Even though collision is uncommon, the association between squamous cell carcinoma and malignant melanoma is very rare compared to basal cell carcinoma and malignant melanoma. Here, we report a case of squamous cell carcinoma with malignant melanoma which was confirmed by histopathological examination and immunohistochemistry. The patient underwent wide local excision and flap cover. This case is reported due to the rarity.
{"title":"Squamomelanocytic tumor of the plantar aspect of the foot: A collision tumor","authors":"J. Pandiaraja, Natarajan Ramya","doi":"10.4103/jdds.jdds_43_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_43_22","url":null,"abstract":"Collision tumors are two cancers that coexist in the same anatomical site. The etiopathogenesis of collision tumors remains controversial. Even though collision is uncommon, the association between squamous cell carcinoma and malignant melanoma is very rare compared to basal cell carcinoma and malignant melanoma. Here, we report a case of squamous cell carcinoma with malignant melanoma which was confirmed by histopathological examination and immunohistochemistry. The patient underwent wide local excision and flap cover. This case is reported due to the rarity.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"29 1","pages":"30 - 33"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82039832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Sharma, P. Choudhary, Rahul Singrodia, M. Verma, P. Rao, D. Kachhawa
Background: Autologous noncultured, nontrypsinized melanocyte–keratinocyte grafting (Jodhpur technique [JT]) is an unconventional innovative surgical modality for the treatment of stable vitiligo. Acral vitiligo is considered an area that is difficult to treat with variable results in different studies. Purpose: The aim of this study was to assess the efficacy and safety of JT in stable acral vitiligo. Methods: This was an open, nonrandomized, and single-arm study. Ninety patches of stable acral vitiligo were included in this study. JT was performed over these patches. The total duration of the study was 48 weeks. The degree of repigmentation was graded into poor (<50% repigmentation), fair (50%–74% repigmentation), good (75%–89% repigmentation), and excellent (90%–100% repigmentation). Results: Out of 90 patches, 81 responded to the surgery. The extent of repigmentation was good to excellent in 61% of patients at week 24 and 70% of patients at week 48. No life-threatening adverse effects were seen. Diffuse pigmentation was seen in 86% of patches. Color match was excellent in most of the patients (91%) with improvement in the Dermatology Life Quality Index (P = 0.0001). Conclusion: JT is a simple, cost-effective, and economical option in the management of stable acral vitiligo with minimal adverse effects.
{"title":"Single arm unicentric study to evaluate the efficacy of autologous noncultured nontrypsinized epidermal cell grafting (Jodhpur technique) in stable acral vitiligo","authors":"D. Sharma, P. Choudhary, Rahul Singrodia, M. Verma, P. Rao, D. Kachhawa","doi":"10.4103/jdds.jdds_15_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_15_21","url":null,"abstract":"Background: Autologous noncultured, nontrypsinized melanocyte–keratinocyte grafting (Jodhpur technique [JT]) is an unconventional innovative surgical modality for the treatment of stable vitiligo. Acral vitiligo is considered an area that is difficult to treat with variable results in different studies. Purpose: The aim of this study was to assess the efficacy and safety of JT in stable acral vitiligo. Methods: This was an open, nonrandomized, and single-arm study. Ninety patches of stable acral vitiligo were included in this study. JT was performed over these patches. The total duration of the study was 48 weeks. The degree of repigmentation was graded into poor (<50% repigmentation), fair (50%–74% repigmentation), good (75%–89% repigmentation), and excellent (90%–100% repigmentation). Results: Out of 90 patches, 81 responded to the surgery. The extent of repigmentation was good to excellent in 61% of patients at week 24 and 70% of patients at week 48. No life-threatening adverse effects were seen. Diffuse pigmentation was seen in 86% of patches. Color match was excellent in most of the patients (91%) with improvement in the Dermatology Life Quality Index (P = 0.0001). Conclusion: JT is a simple, cost-effective, and economical option in the management of stable acral vitiligo with minimal adverse effects.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"72 1","pages":"25 - 29"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79078507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Pagani, Kaitlin Blankenship, D. Goldberg, Riley McLean-Mandell
{"title":"Purse-String closure on the chest, a cosmetically appealing alternative","authors":"K. Pagani, Kaitlin Blankenship, D. Goldberg, Riley McLean-Mandell","doi":"10.4103/jdds.jdds_30_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_30_22","url":null,"abstract":"","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"16 1","pages":"42 - 43"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73118875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Alturki, K. Alekrish, N. Algharbi, Tala Qadoumi, Moath Albusair, Shahad Alghamdi, Asem M. Shadid, Fajer Alzamil, Salma Albarqawi
Background: According to the American Society for Dermatologic Surgery, nearly 12 million dermatological procedures were performed in 2017, of which more than half were cosmetic surgeries. The Saudi population has a positive attitude toward and acceptance of cosmetic surgeries, with a dramatic increase in demand from female patients. Dermatologists are expected to be familiar with several cosmetic procedures, therefore, the quality of residency cosmetic training must be of the highest standards. Purpose: The objective of this study was to assess the experience of dermatologists and dermatology residents regarding cosmetic dermatology training in Saudi Arabia. Methods: A quantitative, cross-sectional, online, questionnaire-based study was conducted from March 2020 to July 2020 among 101 dermatologists and dermatology residents (postgraduate years 2, 3, and 4) in Saudi Arabia. Results: Laser surgery was the most performed procedure (65%), followed by botulinum toxin injection (50%). Experience was lacking and additional training was needed for soft-tissue filling (77%) and chemical peels (60%). A large majority (90%) reported not receiving adequate cosmetic procedures training during their residency. Conclusion: The growing demand for cosmetic operations has increased the need for cosmetic dermatological training. Although most trainees were exposed to esthetic dermatology at some point, this exposure appears inadequate. Improving the curriculum in the dermatology residency program for training in cosmetic procedures may be a priority.
{"title":"Cosmetic dermatology training: Perceptions and experiences of dermatologists and residents in Saudi Arabia","authors":"A. Alturki, K. Alekrish, N. Algharbi, Tala Qadoumi, Moath Albusair, Shahad Alghamdi, Asem M. Shadid, Fajer Alzamil, Salma Albarqawi","doi":"10.4103/jdds.jdds_86_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_86_22","url":null,"abstract":"Background: According to the American Society for Dermatologic Surgery, nearly 12 million dermatological procedures were performed in 2017, of which more than half were cosmetic surgeries. The Saudi population has a positive attitude toward and acceptance of cosmetic surgeries, with a dramatic increase in demand from female patients. Dermatologists are expected to be familiar with several cosmetic procedures, therefore, the quality of residency cosmetic training must be of the highest standards. Purpose: The objective of this study was to assess the experience of dermatologists and dermatology residents regarding cosmetic dermatology training in Saudi Arabia. Methods: A quantitative, cross-sectional, online, questionnaire-based study was conducted from March 2020 to July 2020 among 101 dermatologists and dermatology residents (postgraduate years 2, 3, and 4) in Saudi Arabia. Results: Laser surgery was the most performed procedure (65%), followed by botulinum toxin injection (50%). Experience was lacking and additional training was needed for soft-tissue filling (77%) and chemical peels (60%). A large majority (90%) reported not receiving adequate cosmetic procedures training during their residency. Conclusion: The growing demand for cosmetic operations has increased the need for cosmetic dermatological training. Although most trainees were exposed to esthetic dermatology at some point, this exposure appears inadequate. Improving the curriculum in the dermatology residency program for training in cosmetic procedures may be a priority.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"14 1","pages":"13 - 19"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73475903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Choudhary, R. Mehta, Kamaldeep Singh, Vikas Mahla, B. Ghiya, Divyansha Sharma, Ashok Dhanwal
Background: The spectrum of cutaneous manifestations during the neonatal period varies from transient self-limiting conditions to serious life-threatening ones. Transient and pathological neonatal dermatoses should be differentiated from physiological changes to avoid unnecessary treatment and to relieve parent's stress. Purpose: The aim of this study was to determine the incidence and patterns of various dermatoses in early neonates and correlate these changes with maternal or neonatal factors; in the west region of Rajasthan, India. Methods: This hospital-based prospective study at a tertiary-level referral teaching medical center entailed recording detailed dermatological examination of 5000 early neonates having any physiological and/or pathological cutaneous changes. Results: A total of 5000 newborns were observed, there were 3248 (64.96%) male and 1752 (35.04%) female. Out of the total, 67.36% were full-term birth, whereas 30.44% were preterm and 2.2% were postterm newborns. Physiological skin changes (92.42%) were more commonly observed as compared to pathological changes (45.1%). The physiological skin changes observed in the order of frequency were sebaceous hyperplasia (65.32%), milia (51.12%), and physiological scaling (41.02%). Cutis marmorata (2.06%) and harlequin skin changes (1.06%) were seen more in preterms, weighing <2.5 kg. Miliaria was observed in 39% of neonates, due to the hot and humid environment at our place. Bullous impetigo was the most common infection observed in 199 neonates. The most common iatrogenic complication was caput succedaneum; noted in 160 neonates. Conclusion: Neonatal dermatoses are mostly transient and physiological, but these innocent dermatoses need to be differentiated from serious and aggressive pathological dermatoses to avoid unnecessary therapy.
{"title":"Early neonatal dermatoses: An epidemiological study from a tertiary care center in Western Rajasthan","authors":"P. Choudhary, R. Mehta, Kamaldeep Singh, Vikas Mahla, B. Ghiya, Divyansha Sharma, Ashok Dhanwal","doi":"10.4103/jdds.jdds_89_21","DOIUrl":"https://doi.org/10.4103/jdds.jdds_89_21","url":null,"abstract":"Background: The spectrum of cutaneous manifestations during the neonatal period varies from transient self-limiting conditions to serious life-threatening ones. Transient and pathological neonatal dermatoses should be differentiated from physiological changes to avoid unnecessary treatment and to relieve parent's stress. Purpose: The aim of this study was to determine the incidence and patterns of various dermatoses in early neonates and correlate these changes with maternal or neonatal factors; in the west region of Rajasthan, India. Methods: This hospital-based prospective study at a tertiary-level referral teaching medical center entailed recording detailed dermatological examination of 5000 early neonates having any physiological and/or pathological cutaneous changes. Results: A total of 5000 newborns were observed, there were 3248 (64.96%) male and 1752 (35.04%) female. Out of the total, 67.36% were full-term birth, whereas 30.44% were preterm and 2.2% were postterm newborns. Physiological skin changes (92.42%) were more commonly observed as compared to pathological changes (45.1%). The physiological skin changes observed in the order of frequency were sebaceous hyperplasia (65.32%), milia (51.12%), and physiological scaling (41.02%). Cutis marmorata (2.06%) and harlequin skin changes (1.06%) were seen more in preterms, weighing <2.5 kg. Miliaria was observed in 39% of neonates, due to the hot and humid environment at our place. Bullous impetigo was the most common infection observed in 199 neonates. The most common iatrogenic complication was caput succedaneum; noted in 160 neonates. Conclusion: Neonatal dermatoses are mostly transient and physiological, but these innocent dermatoses need to be differentiated from serious and aggressive pathological dermatoses to avoid unnecessary therapy.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"16 1","pages":"6 - 12"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90231882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The prevalence of depression among adolescents and young adults with acne vulgaris has varied widely in different studies. Purpose: The purpose of this study is to assess the prevalence of depression among adolescents with acne vulgaris as compared to age and gender-matched healthy adolescents. The effects of the severity of acne (and postacne scars), duration of acne, and treatment on the severity of depression among adolescents with acne have also been assessed in this study. Methods: The patient health questionnaire-9 was completed by each one of 1502 adolescents with acne vulgaris and 1500 age and gender-matched controls in this cross-sectional study. The association of prevalence and severity of depression with gender, duration of acne, grade of acne, treatments received, and presence and severity of postacne scars was explored by Chi-square test for categorical variables and t-test for quantitative variables. Results: One hundred and thirty (8.65%) adolescents with acne vulgaris were diagnosed with depression, while only 5 (0.33%) healthy adolescents were diagnosed with depression (P = 0.005). Among adolescents with acne vulgaris, 2 (0.13%) had severe depression, 4 (0.27%) had moderately severe depression, 11 (0.73%) had moderate depression, and 113 (7.52%) had mild depression. There was no association of severity of depression with gender, grade of acne (and postacne scars), duration of acne, and treatment received. Conclusion: Acne and postacne scars are associated with a significant prevalence of depression among adolescents with acne independent of treatment received. Clinicians should consider incorporating depression screening and referral system in their workflow with adolescents who access them for acne treatment to achieve better clinical outcomes.
{"title":"Depression among adolescents with acne vulgaris: A cross-sectional assessment","authors":"I. Singh, A. Masih","doi":"10.4103/jdds.jdds_77_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_77_22","url":null,"abstract":"Background: The prevalence of depression among adolescents and young adults with acne vulgaris has varied widely in different studies. Purpose: The purpose of this study is to assess the prevalence of depression among adolescents with acne vulgaris as compared to age and gender-matched healthy adolescents. The effects of the severity of acne (and postacne scars), duration of acne, and treatment on the severity of depression among adolescents with acne have also been assessed in this study. Methods: The patient health questionnaire-9 was completed by each one of 1502 adolescents with acne vulgaris and 1500 age and gender-matched controls in this cross-sectional study. The association of prevalence and severity of depression with gender, duration of acne, grade of acne, treatments received, and presence and severity of postacne scars was explored by Chi-square test for categorical variables and t-test for quantitative variables. Results: One hundred and thirty (8.65%) adolescents with acne vulgaris were diagnosed with depression, while only 5 (0.33%) healthy adolescents were diagnosed with depression (P = 0.005). Among adolescents with acne vulgaris, 2 (0.13%) had severe depression, 4 (0.27%) had moderately severe depression, 11 (0.73%) had moderate depression, and 113 (7.52%) had mild depression. There was no association of severity of depression with gender, grade of acne (and postacne scars), duration of acne, and treatment received. Conclusion: Acne and postacne scars are associated with a significant prevalence of depression among adolescents with acne independent of treatment received. Clinicians should consider incorporating depression screening and referral system in their workflow with adolescents who access them for acne treatment to achieve better clinical outcomes.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"17 10","pages":"20 - 24"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72546470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pityriasis lichenoides (PL) presents a spectrum of uncommon inflammatory skin diseases that includes acute and chronic variants. The hypopigmented PL is a rare variant that was reported in dark-skinned individuals. It was proved histologically to be a variant of PL chronica (PLC). To our best knowledge, we report the first case of a hypopigmented variant of PL that shows histopathological features of PLC and PL et varioliformis acuta.
{"title":"Hypopigmented pityriasis lichenoides: A new clinicopathological type","authors":"A. Mahran, Aya Younis, A. Ahmed, Marwa Mekkawy","doi":"10.4103/jdds.jdds_48_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_48_22","url":null,"abstract":"Pityriasis lichenoides (PL) presents a spectrum of uncommon inflammatory skin diseases that includes acute and chronic variants. The hypopigmented PL is a rare variant that was reported in dark-skinned individuals. It was proved histologically to be a variant of PL chronica (PLC). To our best knowledge, we report the first case of a hypopigmented variant of PL that shows histopathological features of PLC and PL et varioliformis acuta.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"56 1","pages":"34 - 36"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78409112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malak Aldosari, A. Saleh, Abdubadie Kutubi, Asma Al-Ruhaimi, Y. Bashawri, Arwa Althubyani, Raneem Saleh, H. Khalil
Background: Hirsutism is the excessive body or facial terminal (coarse) hair growth in females in a male-like pattern, carries a worldwide prevalence of 5%–20%, and requires careful evaluation and long-term management. Purpose: The study aims to critically appraise public and private institutions' practices in managing hirsutism, compared against international standards. The purpose of this study was to assess how frequently patients receive counseling to address the causes of hirsutism and to determine if disease severity, screening, and outpatient management vary between public and private clinics in Saudi Arabia. Methods: Patients were recruited from gynecology, endocrine, dermatology, and women's skin care clinics in public (n = 119) and private outpatient clinics (n = 238). Sociodemographics, body mass index (BMI), menstrual cycle rhythm, hirsutism site and scores, associated acne and/or alopecia, family history, and treatment modality received were queried. This study had two groups: Group 1 (n = 119) patients who were seen at public outpatient clinics and Group 2 (n = 238) patients who were seen at private outpatient clinics. Results: The median age was 27 years (range 18–45) and median BMI was 25 kg/m2 (range 16–44). The total mean hirsutism score was 9.3 ± 3.8. The severity of hirsutism was categorized into three groups: mild cases were recorded in 224 women (62.7%), moderate cases were recorded in 94 women (26.3%), and severe cases were recorded in 39 women (10.9%). There was no significant correlation between total mean hirsutism scores, age and BMI, P = 0.5 and P = 0.2, respectively. Approximately one-third of women were seen and investigated by physicians either at public or private clinics and about 70% of women were seen and treated by nonphysician skin care specialist without prior medical investigations in either public or private outpatient departments (OPDs). Conclusion: Assessment and management of hirsutism are similar in the public and private setting. Most patients presented to private rather than public OPDs and were not appropriately investigated for hirsutism. Weight reduction can be beneficial for the management of hirsutism for those with raised BMI and advice should be given accordingly in the OPD setting.
{"title":"An evaluation of the management of hirsutism in public versus private outpatient departments in Saudi Arabia","authors":"Malak Aldosari, A. Saleh, Abdubadie Kutubi, Asma Al-Ruhaimi, Y. Bashawri, Arwa Althubyani, Raneem Saleh, H. Khalil","doi":"10.4103/jdds.jdds_47_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_47_22","url":null,"abstract":"Background: Hirsutism is the excessive body or facial terminal (coarse) hair growth in females in a male-like pattern, carries a worldwide prevalence of 5%–20%, and requires careful evaluation and long-term management. Purpose: The study aims to critically appraise public and private institutions' practices in managing hirsutism, compared against international standards. The purpose of this study was to assess how frequently patients receive counseling to address the causes of hirsutism and to determine if disease severity, screening, and outpatient management vary between public and private clinics in Saudi Arabia. Methods: Patients were recruited from gynecology, endocrine, dermatology, and women's skin care clinics in public (n = 119) and private outpatient clinics (n = 238). Sociodemographics, body mass index (BMI), menstrual cycle rhythm, hirsutism site and scores, associated acne and/or alopecia, family history, and treatment modality received were queried. This study had two groups: Group 1 (n = 119) patients who were seen at public outpatient clinics and Group 2 (n = 238) patients who were seen at private outpatient clinics. Results: The median age was 27 years (range 18–45) and median BMI was 25 kg/m2 (range 16–44). The total mean hirsutism score was 9.3 ± 3.8. The severity of hirsutism was categorized into three groups: mild cases were recorded in 224 women (62.7%), moderate cases were recorded in 94 women (26.3%), and severe cases were recorded in 39 women (10.9%). There was no significant correlation between total mean hirsutism scores, age and BMI, P = 0.5 and P = 0.2, respectively. Approximately one-third of women were seen and investigated by physicians either at public or private clinics and about 70% of women were seen and treated by nonphysician skin care specialist without prior medical investigations in either public or private outpatient departments (OPDs). Conclusion: Assessment and management of hirsutism are similar in the public and private setting. Most patients presented to private rather than public OPDs and were not appropriately investigated for hirsutism. Weight reduction can be beneficial for the management of hirsutism for those with raised BMI and advice should be given accordingly in the OPD setting.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"51 1","pages":"1 - 5"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74438252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Khan, Ayesha Sharmeen, S. Amin, Bushra Siddiqui
Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood having clinical and histological features of Greither's disease (GD). Only a single report of adult-onset GD has been reported in the literature. All patients presenting with palmoplantar keratoderma should be thoroughly evaluated, as it may be a late-onset inherited disorder, it adds to the spectrum of conditions to presenting with PPKs of late-onset.
{"title":"Adult-Onset greither's disease: A rare report of two cases","authors":"H. Khan, Ayesha Sharmeen, S. Amin, Bushra Siddiqui","doi":"10.4103/jdds.jdds_76_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_76_22","url":null,"abstract":"Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood having clinical and histological features of Greither's disease (GD). Only a single report of adult-onset GD has been reported in the literature. All patients presenting with palmoplantar keratoderma should be thoroughly evaluated, as it may be a late-onset inherited disorder, it adds to the spectrum of conditions to presenting with PPKs of late-onset.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"5 1","pages":"39 - 41"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89550331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilek Menteşoğlu, H. Khurami, A. Karaduman, Ö. Gököz
Perforating granuloma annulare (PGA) is a infrequent type of granuloma annulare. PGA has a chronic course. The etiology and perforation mechanism are still obscure. We submit a case of a 32-year-old male patient who presented with a 2-month history of asymptomatic lesion on the dorsum of his hand. He did not report the use of any medication, infection, vaccine, trauma, autoimmune disorders, heart disease, and malignancy. Complete blood count, thyroid function tests, lipid profile parameters, and fasting blood glucose were within normal ranges. Moreover, the human immunodeficiency virüs was negative. Histopathologic examination revealed that accumulation of mucin was at the center of the histiocytic reaction, which was grouped in places. Therefore, we diagnosed PGA with clinical and histopathological data. The presented case emphasizes that PGA should be considered in the differential diagnosis of keratotic/ umbilical papules on the dorsum of the hand.
{"title":"Perforating granuloma annulare mimicking keratoacanthoma: A case report","authors":"Dilek Menteşoğlu, H. Khurami, A. Karaduman, Ö. Gököz","doi":"10.4103/jdds.jdds_16_22","DOIUrl":"https://doi.org/10.4103/jdds.jdds_16_22","url":null,"abstract":"Perforating granuloma annulare (PGA) is a infrequent type of granuloma annulare. PGA has a chronic course. The etiology and perforation mechanism are still obscure. We submit a case of a 32-year-old male patient who presented with a 2-month history of asymptomatic lesion on the dorsum of his hand. He did not report the use of any medication, infection, vaccine, trauma, autoimmune disorders, heart disease, and malignancy. Complete blood count, thyroid function tests, lipid profile parameters, and fasting blood glucose were within normal ranges. Moreover, the human immunodeficiency virüs was negative. Histopathologic examination revealed that accumulation of mucin was at the center of the histiocytic reaction, which was grouped in places. Therefore, we diagnosed PGA with clinical and histopathological data. The presented case emphasizes that PGA should be considered in the differential diagnosis of keratotic/ umbilical papules on the dorsum of the hand.","PeriodicalId":15535,"journal":{"name":"Journal of Dermatology and Dermatologic Surgery","volume":"87 1","pages":"37 - 38"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85463029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}