呼吁在纳米医学研究中改进翻译

Deniz A. Bölükbas, S. Meiners
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引用次数: 1

摘要

纳米颗粒作为新型诊断和治疗工具的使用在癌症治疗领域引起了极大的关注。纳米疗法提供了许多可能性,如增强药物溶解度和稳定性,延长循环时间,组织、细胞、细胞器特异性靶向,疾病的早期检测和监测,刺激控制的药物释放和多种药物的共同递送,所有这些都有助于更安全的药物递送,并将剂量限制的副作用降到最低。几种具有这些特性的纳米药物已经上市,还有许多其他药物正在研发中。
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Calling for improved translation in nanomedical research
The use of nanoparticles as novel diagnostic and therapeutic tools has gained immense attention in the field of cancer management. Nano-based therapies offer numerous possibilities such as enhanced drug solubility and stability, extended circulation times, tissue, cell, organelle-specific targeting, early detection and monitoring of diseases, stimuli-controlled drug release and co-delivery of multiple agents, all contributing to a safer drug delivery with minimized dose-limiting side-effects [1]. Several nanomedicines bearing these features are already on the market with many others following in the pipeline.
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